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Atomic environment fingerprints are widely used in computational materials science, from machine learning potentials to the quantification of similarities between atomic configurations. Many approaches to the construction of such…

Computational molecular representations underpin virtual screening, property prediction, and materials discovery. Conventional fingerprints are efficient and deterministic but lose structural information through hash-based compression,…

Machine Learning · Computer Science 2026-05-01 Jonas Teufel , Luca Torresi , André Eberhard , Pascal Friederich

Scanning tunneling and atomic force microscopies (STM/nc-AFM) are rapidly progressing to offer unprecedented spatial resolution of a diverse array of chemical species. In particular, they are employed to characterize on-surface chemical…

Mesoscale and Nanoscale Physics · Physics 2022-05-12 Jack Hellerstedt , Aleš Cahlík , Martin Švec , Oleksandr Stetsovych , Tyler Hennen

The simulation of intrinsic contributions to molecular properties holds the potential to allow for chemistry to be directly inferred from changes to electronic structures at the atomic level. In the present study, we demonstrate how such…

Chemical Physics · Physics 2023-08-16 Frederik Ø. Kjeldal , Janus J. Eriksen

Infrared spectroscopy, especially for molecular vibrations in the fingerprint region between 600 and 1500 cm-1, is a powerful characterization method for bulk materials. However, molecular fingerprinting at the nanoscale level still remains…

Optics · Physics 2016-08-24 Hai Hu , Xiaoxia Yang , Feng Zhai , Debo Hu , Ruina Liu , Kaihui Liu , Zhipei Sun , Qing Dai

Fingerprinting codes are a crucial tool for proving lower bounds in differential privacy. They have been used to prove tight lower bounds for several fundamental questions, especially in the ``low accuracy'' regime. Unlike…

Data Structures and Algorithms · Computer Science 2024-12-20 Xin Lyu , Kunal Talwar

One of the key requirements for incorporating machine learning into the drug discovery process is complete reproducibility and traceability of the model building and evaluation process. With this in mind, we have developed an end-to-end…

Fingerprinting refers to the process of identifying underlying Machine Learning (ML) models of AI Systemts, such as Large Language Models (LLMs), by analyzing their unique characteristics or patterns, much like a human fingerprint. The…

Machine Learning · Computer Science 2025-02-10 Devansh Bhardwaj , Naman Mishra

We introduce a new type of cryptographic primitive that we call hiding fingerprinting. A (quantum) fingerprinting scheme translates a binary string of length $n$ to $d$ (qu)bits, typically $d\ll n$, such that given any string $y$ and a…

Quantum Physics · Physics 2022-03-30 Dmytro Gavinsky , Tsuyoshi Ito

Fingerprint recognition is widely used for verification and identification in many commercial, governmental and forensic applications. The orientation field (OF) plays an important role at various processing stages in fingerprint…

Computer Vision and Pattern Recognition · Computer Science 2018-01-26 Carsten Gottschlich , Benjamin Tams , Stephan Huckemann

Deep neural networks are vulnerable to adversarial examples, which dramatically alter model output using small input changes. We propose Neural Fingerprinting, a simple, yet effective method to detect adversarial examples by verifying…

Machine Learning · Computer Science 2019-06-18 Sumanth Dathathri , Stephan Zheng , Tianwei Yin , Richard M. Murray , Yisong Yue

Recently, Graph Transformer (GT) models have been widely used in the task of Molecular Property Prediction (MPP) due to their high reliability in characterizing the latent relationship among graph nodes (i.e., the atoms in a molecule).…

Machine Learning · Computer Science 2023-10-12 Wentao Yu , Shuo Chen , Chen Gong , Gang Niu , Masashi Sugiyama

As protein therapeutics play an important role in almost all medical fields, numerous studies have been conducted on proteins using artificial intelligence. Artificial intelligence has enabled data driven predictions without the need for…

Quantitative Methods · Quantitative Biology 2023-03-30 Myeonghun Lee , Kyoungmin Min

In the majority of molecular optimization tasks, predictive machine learning (ML) models are limited due to the unavailability and cost of generating big experimental datasets on the specific task. To circumvent this limitation, ML models…

Chemical space which encompasses all stable compounds is unfathomably large and its dimension scales linearly with the number of atoms considered. The success of machine learning methods suggests that many physical quantities exhibit…

Chemical Physics · Physics 2025-07-04 Ali Banjafar , Guido Falk von Rudorff

We have developed an extended distance matrix approach to study the molecular geometric configuration through spectral decomposition. It is shown that the positions of all atoms in the eigen-space can be specified precisely by their…

Materials Science · Physics 2017-05-24 Xiao-Tian Li , Xiao-bao Yang , Yu-Jun Zhao

Predicting molecular properties (e.g., atomization energy) is an essential issue in quantum chemistry, which could speed up much research progress, such as drug designing and substance discovery. Traditional studies based on density…

Computational Physics · Physics 2019-08-20 Chengqiang Lu , Qi Liu , Chao Wang , Zhenya Huang , Peize Lin , Lixin He

Fast and accurate molecular force field (FF) parameterization is still an unsolved problem. Accurate FFs are not generally available for all molecules, like novel druglike molecules. While methods based on quantum mechanics (QM) exist to…

Chemical Physics · Physics 2019-08-06 Raimondas Galvelis , Stefan Doerr , Joao M. Damas , Matt J. Harvey , Gianni De Fabritiis

A common approach to the de novo molecular generation problem from mass spectra involves a two-stage pipeline: (1) encoding mass spectra into molecular fingerprints, followed by (2) decoding these fingerprints into molecular structures. In…

Machine Learning · Computer Science 2025-11-04 Neng Kai Nigel Neo , Lim Jing , Ngoui Yong Zhau Preston , Koh Xue Ting Serene , Bingquan Shen

Computational methods that operate on three-dimensional molecular structure have the potential to solve important questions in biology and chemistry. In particular, deep neural networks have gained significant attention, but their…