English
Related papers

Related papers: Some reflections on the test-negative design

200 papers

It has been one year since the outbreak of the COVID-19 pandemic. The good news is that vaccines developed by several manufacturers are being actively distributed worldwide. However, as more and more vaccines become available to the public,…

Social and Information Networks · Computer Science 2021-07-07 Wei Wu , Hanjia Lyu , Jiebo Luo

With the increasing spread of COVID-19, it is important to systematically test more and more people. The current strategy for test-kit allocation is mostly rule-based, focusing on individuals having (a) symptoms for COVID-19, (b) travel…

Artificial Intelligence · Computer Science 2020-04-07 Arpita Biswas , Shruthi Bannur , Prateek Jain , Srujana Merugu

The debate around vaccines has been going on for decades, but the COVID-19 pandemic showed how crucial it is to understand and mitigate anti-vaccine sentiments. While the pandemic may be over, it is still important to understand how the…

Social and Information Networks · Computer Science 2024-04-03 Soham Poddar , Rajdeep Mukherjee , Subhendu Khatuya , Niloy Ganguly , Saptarshi Ghosh

The lack of quantitative risk assessment of airborne transmission of COVID-19 under practical settings leads to large uncertainties and inconsistencies in our preventive measures. Combining in situ measurements and numerical simulations, we…

Medical Physics · Physics 2020-07-27 Siyao Shao , Dezhi Zhou , Ruichen He , Jiaqi Li , Shufan Zou , Kevin Mallery , Santosh Kumar , Suo Yang , Jiarong Hong

Statistical methods are developed for analysis of clinical and virus genetics data from phase 3 randomized, placebo-controlled trials of vaccines against novel coronavirus COVID-19. Vaccine efficacy (VE) of a vaccine to prevent COVID-19…

Methodology · Statistics 2022-01-25 Fei Heng , Yanqing Sun , Peter B. Gilbert

Pandemic response is a complex affair. Most governments employ a set of quasi-standard measures to fight COVID-19 including wearing masks, social distancing, virus testing and contact tracing. We argue that some non-trivial factors behind…

Theoretical Economics · Economics 2020-10-21 Balazs Pejo , Gergely Biczok

There are many hard-to-reconcile numbers circulating concerning Covid-19. Using reports from random testing, the fatality ratio per infection is evaluated and used to extract further information on the actual fraction of infections and the…

Populations and Evolution · Quantitative Biology 2020-05-25 Allen Caldwell , Vasyl Hafych , Oliver SChulz , Lolian Shtembari

In this paper we discuss quantum-like decision-making experiments using negative probabilities. We do so by showing how the two-slit experiment, in the simplified version of the Mach-Zehnder interferometer, can be described by this…

Data Analysis, Statistics and Probability · Physics 2015-06-19 J. Acacio de Barros , Gary Oas

Testing of symptomatic persons for infection with SARS-CoV-2 is occurring worldwide. We propose two types of case-control studies that can be carried out jointly in test-settings for symptomatic persons. The first, the test-negative…

Populations and Evolution · Quantitative Biology 2021-06-08 Jan P Vandenbroucke , Elizabeth B Brickley , Christina M J E Vandenbroucke-Grauls , Neil Pearce

The COVID-19 Pandemic has left a devastating trail all over the world, in terms of loss of lives, economic decline, travel restrictions, trade deficit, and collapsing economy including real-estate, job loss, loss of health benefits, the…

Purpose of Review: Negative controls are a powerful tool to detect and adjust for bias in epidemiological research. This paper introduces negative controls to a broader audience and provides guidance on principled design and causal analysis…

Methodology · Statistics 2022-07-20 Xu Shi , Wang Miao , Eric Tchetgen Tchetgen

Although multiple COVID-19 vaccines have been available for several months now, vaccine hesitancy continues to be at high levels in the United States. In part, the issue has also become politicized, especially since the presidential…

Social and Information Networks · Computer Science 2021-11-11 Yuesheng Luo , Mayank Kejriwal

The outbreak of the novel Coronavirus Disease 2019 (COVID-19) has lasted for nearly two years and caused unprecedented impacts on people's daily life around the world. Even worse, the emergence of the COVID-19 Delta variant once again puts…

Computers and Society · Computer Science 2021-11-09 Hui Yin , Xiangyu Song , Shuiqiao Yang , Jianxin Li

Since the beginning of the vaccination trial, social media has been flooded with anti-vaccination comments and conspiracy beliefs. As the day passes, the number of COVID- 19 cases increases, and online platforms and a few news portals…

Computers and Society · Computer Science 2025-10-14 Md Hasibul Amin , Harika Madanu , Sahithi Lavu , Hadi Mansourifar , Dana Alsagheer , Weidong Shi

The Covid-19 pandemic has led to infodemic of low quality information leading to poor health decisions. Combating the outcomes of this infodemic is not only a question of identifying false claims, but also reasoning about the decisions…

Computation and Language · Computer Science 2022-08-11 Maria Leonor Pacheco , Tunazzina Islam , Monal Mahajan , Andrey Shor , Ming Yin , Lyle Ungar , Dan Goldwasser

With a substantial proportion of the population currently hesitant to take the COVID-19 vaccine, it is important that people have access to accurate information. However, there is a large amount of low-credibility information about vaccines…

The COVID-19 pandemic has led to a need for widespread and rapid vaccine development. As several vaccines have recently been approved for human use or are in different stages of development, governments across the world are preparing…

Optimal use and distribution of Covid-19 vaccines involves adjustments of dosing. Due to the rapidly-evolving pandemic, such adjustments often need to be introduced before full efficacy data are available. As demonstrated in other areas of…

Quantitative Methods · Quantitative Biology 2021-08-17 Mario Giorgi , Rajat Desikan , Piet H. van der Graaf , Andrzej M. Kierzek

Vaccine hesitancy is widespread, despite the government's information campaigns and the efforts of the World Health Organisation (WHO). Categorising the topics within vaccine-related narratives is crucial to understand the concerns…

Computation and Language · Computer Science 2023-11-20 Yue Li , Carolina Scarton , Xingyi Song , Kalina Bontcheva

Dialogue systems are widely used in AI to support timely and interactive communication with users. We propose a general-purpose dialogue system architecture that leverages computational argumentation to perform reasoning and provide…

Computation and Language · Computer Science 2021-10-18 Bettina Fazzinga , Andrea Galassi , Paolo Torroni