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Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

In recent years, nonreciprocally coupled systems have received growing attention. Previous work has shown that the interplay of nonreciprocal coupling and Goldstone modes can drive the emergence of temporal order such as traveling waves. We…

First time in six decades, uncountable infinite exact solutions of FitzHugh-Nagumo model with diffusion have been found. FitzHugh-Nagumo model is a nonlinear dynamical system applicable to neurosciences, chemical kinetics, cell division,…

A qualitative model is presented, suggesting gravitational information is transduced into biological systems primarily by its effect on spatially organised membrane and cytoplasmic flows. Continuous low affinity interactions between…

Inspired by active shape morphing in developing tissues and biomaterials, we investigate two generic mechanochemical models where the deformations of a thin elastic sheet are driven by, and in turn affect, the concentration gradients of a…

The idealisation of neuronal pulses as $\delta$-spikes is a convenient approach in neuroscience but can sometimes lead to erroneous conclusions. We investigate the effect of a finite pulse-width on the dynamics of balanced neuronal…

Valveless pumping assists in fluid transport in various organisms and engineering systems. In a previous work, to study the actuator impact effects on valveless pumping, we constructed a piecewise-linear lumped-parameter model for a…

Frictional sliding is an intrinsically complex phenomenon, emerging from the interplay between driving forces, elasto-frictional instabilities, interfacial nonlinearity and dissipation, material inertia and bulk geometry. We show that…

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Synaptic connections in neuronal circuits are modulated by pre- and post-synaptic spiking activity. Heuristic models of this process of synaptic plasticity can provide excellent fits to results from in-vitro experiments in which pre- and…

Generating molecular graphs is crucial in drug design and discovery but remains challenging due to the complex interdependencies between nodes and edges. While diffusion models have demonstrated their potentiality in molecular graph design,…

Building a virtual cell capable of accurately simulating cellular behaviors in silico has long been a dream in computational biology. We introduce CellFlux, an image-generative model that simulates cellular morphology changes induced by…

Consider the motion of a thin layer of electrically conducting fluid, between two closely spaced parallel plates, in a classical Hele-Shaw geometry. Furthermore, let the system be immersed in a uniform external magnetic field (normal to the…

The actomyosin cytoskeleton, a protein assembly comprising actin fibers and the myosin molecular motor, drives various cellular dynamics through contractile force generation at high densities. However, the relationship between the density…

Fast and realistic coupling of blood flow and vessel wall is of great importance to virtual surgery. In this paper, we propose a novel data-driven coupling method that formulates physics-based blood flow simulation as a regression problem,…

The generation of action potential brings into play specific mechanosensory stimuli manifest in the variation of membrane capacitance, resulting from the selective membrane permeability to ions exchanges and testifying to the central role…

We investigate feedback control of the cooperative dynamics of two coupled neural oscillators that is induced merely by external noise. The interacting neurons are modelled as FitzHugh-Nagumo systems with parameter values at which no…

The interaction of targeted drug carriers with epithelial and endothelial barriers in vivo is largely determined by the dynamics of the body fluids. To simulate these conditions in binding assays, a fully biocompatible in vitro model was…

Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

We investigate diffusion-driven instabilities in a FitzHugh-Nagumo reaction-diffusion system with superdiffusive transport, modeled by fractional Laplacian operators with different diffusion orders for the activator and the inhibitor. A…