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It is suggested that the propagation of the action potential is accompanied by an axoplasmic pressure pulse propagating in the axoplasm along the axon length. The pressure pulse stretch-modulates voltage-gated Na (Nav) channels embedded in…

Biological Physics · Physics 2010-07-07 Marat M. Rvachev

Internal haemorrhage, often leading to cardio-vascular arrest happens to be one of the prime sources of high fatality rates in mammals. We propose a simplistic model of fluid flow to specify the location of the haemorrhagic spots, which, if…

Soft Condensed Matter · Physics 2013-04-01 Amit K. Chattopadhyay , Shreekantha Sil

Two-dimensional laminar flow of a viscous fluid induced by peristalsis due to a moving wall wave has been studied previously for a rectangular channel, a circular tube, and a concentric circular annulus. Here we study peristaltic flow in a…

Fluid Dynamics · Physics 2020-07-30 J. Brennen Carr , John H. Thomas , Jia Liu , Jessica K. Shang

Neurons are the central biological objects in understanding how the brain works. The famous Hodgkin-Huxley model, which describes how action potentials of a neuron are initiated and propagated, consists of four coupled nonlinear…

Neurons and Cognition · Quantitative Biology 2010-02-01 William Hanan , Dhagash Mehta , Guillaume Moroz , Sepanda Pouryahya

Characterizing the dynamics of a cantilever in channel flow is relevant to applications ranging from snoring to energy harvesting. Aeroelastic flutter induces large oscillating amplitudes and sharp changes with frequency that impact the…

Fluid Dynamics · Physics 2019-03-11 Luis Phillipe Tosi , Tim Colonius

The flow driven by a rapidly expanding and collapsing cavitation bubble in a narrow cylindrical gap is studied with the volume of fluid method. The simulations reveal a developing plug flow during the early expansion followed by flow…

Fluid Dynamics · Physics 2017-02-01 Milad Mohammadzadeh , Fenfang Li , Claus-Dieter Ohl

In this work, receiver diversity in advection-dominated diffusion-advection channels is investigated. Strong directed flow fundamentally alters the communication-theoretic properties of molecular communication systems (MC). Specifically,…

Signal Processing · Electrical Eng. & Systems 2026-02-02 Fatih Merdan , Ozgur B. Akan

We characterize numerically the regime of anticipated synchronization in the coupled FitzHugh-Nagumo model for neurons. We consider two neurons, coupled unidirectionally (in a master-slave configuration), subject to the same random external…

Condensed Matter · Physics 2009-11-07 Raul Toral , C. Masoller , Claudio R. Mirasso , M. Ciszak , O. Calvo

We study the transport properties of disordered two-dimensional electron systems with a perfectly conducting channel. We introduce an asymmetric Chalker-Coddington network model and numerically investigate the point-contact conductance. We…

Mesoscale and Nanoscale Physics · Physics 2009-07-27 Koji Kobayashi , Tomi Ohtsuki , Keith Slevin

We study the steady flow-induced deformation between an incompressible non-Newtonian fluid and a three-dimensional (3D) deformable channel. Specifically, we provide a comprehensive experimental--theoretical framework for such flows of…

Fluid Dynamics · Physics 2025-09-04 SungGyu Chun , Ivan C. Christov , Jie Feng

Although materials and processes are different from biological cells', brain mimicries led to tremendous achievements in massively parallel information processing via neuromorphic engineering. Inexistent in electronics, we describe how to…

Disordered Systems and Neural Networks · Physics 2022-01-05 Kamila Janzakova , Ankush Kumar , Mahdi Ghazal , Anna Susloparova , Yannick Coffinier , Fabien Alibart , Sebastien Pecqueur

We present a novel framework to explore neural control and design of complex fluidic systems with dynamic solid boundaries. Our system features a fast differentiable Navier-Stokes solver with solid-fluid interface handling, a…

Fluid Dynamics · Physics 2024-11-04 Yifei Li , Yuchen Sun , Pingchuan Ma , Eftychios Sifakis , Tao Du , Bo Zhu , Wojciech Matusik

Peristaltic pumping is hypothesized to drive fluid transport in several physiological systems, including cerebrospinal fluid flow through cerebral perivascular spaces (PVSs). Cerebral PVSs are unique in the context of peristaltic pumping…

Fluid Dynamics · Physics 2026-05-28 Shahaf Ella Salach , Ron Shnapp

The in silico simulations are widely used in contemporary systems biology including the analysis of nerve pulse propagation. As known from numerous experiments, the propagation of an action potential is accompanied by mechanical and thermal…

Biological Physics · Physics 2020-09-21 Jüri Engelbrecht , Kert Tamm , Tanel Peets

Active nematic models explain the topological defects and flow patterns observed in epithelial tissues, but the nature of active stress-whether it is extensile or contractile, a key parameter of the theory-is not well established…

Soft Condensed Matter · Physics 2025-11-11 Jan Rozman , Sumesh P. Thampi , Julia M. Yeomans

Aging is driven by subcellular processes that are relatively well-understood. However the qualitative mechanisms and quantitative dynamics of how these micro-level failures cascade to a macro-level catastrophe in a tissue or organs remain…

Tissues and Organs · Quantitative Biology 2021-02-03 Gurdip Uppal , Gokhan Bahcecioglu , Pinar Zorlutuna , Dervis Can Vural

Many multicellular communities propagate signals in a directed manner via excitable waves. Cell-to-cell heterogeneity is a ubiquitous feature of multicellular communities, but the effects of heterogeneity on wave propagation are still…

Biological Physics · Physics 2020-04-22 Xiaoling Zhai , Joseph W. Larkin , Gürol M. Süel , Andrew Mugler

In nature, excitable reaction-diffusion systems found in diverse settings (e.g. chemical reactions, metal rust, yeast, amoeba, heart, brain) generate geometrically similar macroscopic waves(1,2). For the heart and brain, the spatiotemporal…

Tissues and Organs · Quantitative Biology 2015-08-12 Rebecca A. B. Burton , Alekxandra Klimas , Christina M. Ambrosi , Emilia Entcheva , Gil Bub

Fifty years ago, Fitzugh introduced a phase portrait that became famous for a twofold reason: it captured in a physiological way the qualitative behavior of Hodgkin-Huxley model and it revealed the power of simple dynamical models to unfold…

Dynamical Systems · Mathematics 2011-12-13 Alessio Franci , Guillaume Drion , Vincent Seutin , Rodolphe Sepulchre

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett