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We study time-optimal protocols for controlling quantum systems which show several avoided level crossings in their energy spectrum. The structure of the spectrum allows us to generate a robust guess which is time-optimal at each crossing.…

Quantum Physics · Physics 2015-11-18 P. M. Poggi , F. C. Lombardo , D. A. Wisniacki

Oncolytic virotherapy is an experimental cancer treatment that uses genetically engineered viruses to target and kill cancer cells. One major limitation of this treatment is that virus particles are rapidly cleared by the immune system,…

Cell Behavior · Quantitative Biology 2019-12-02 Adrianne L. Jenner , Chae-Ok Yun , Peter S. Kim , Adelle C. F. Coster

Many phenomena in physics, chemistry, and biology involve seeking an optimal control to maximize an objective for a classical or quantum system which is open and interacting with its environment. The complexity of finding an optimal control…

Quantum Physics · Physics 2010-11-08 Alexander Pechen , Herschel Rabitz

In this paper, we introduce a novel pseudospectral method for the numerical solution of optimal control problems governed by a parabolic distributed parameter system. The infinite-dimensional optimal control problem is reduced into a…

Optimization and Control · Mathematics 2023-03-06 Kareem T. Elgindy

We establish the existence of an optimal control for a general class of singular control problems with state constraints. The proof uses weak convergence arguments and a time rescaling technique. The existence of optimal controls for…

Probability · Mathematics 2007-05-23 Amarjit Budhiraja , Kevin Ross

The paper considers the problems of optimal vaccination control in the classical SIR model under constraints on the resource capabilities of the insurance medical system, in particular under constraints on the possible absolute rate of…

Optimization and Control · Mathematics 2025-11-24 Bogdan Norkin , Vladimir Norkin

In this article, the feasibility of using optimal control theory will be studied to develop control theoretic methods for personalized treatment of HCV patients. The mathematical model for HCV progression includes compartments for healthy…

Optimization and Control · Mathematics 2023-09-07 Anh-Tuan Nguyen , Hien Tran

This paper investigates the optimal control problem for a class of parabolic equations where the diffusion coefficient is influenced by a control function acting nonlocally. Specifically, we consider the optimization of a cost functional…

Optimization and Control · Mathematics 2025-03-11 Stefana-Lucia Anita , Luca Di Persio

The aim of this notes is to give a concise introduction to control theory for systems governed by stochastic partial differential equations. We shall mainly focus on controllability and optimal control problems for these systems. For the…

Optimization and Control · Mathematics 2021-01-27 Qi Lü , Xu Zhang

We propose a general framework for studying optimal impulse control problem in the presence of uncertainty on the parameters. Given a prior on the distribution of the unknown parameters, we explain how it should evolve according to the…

Probability · Mathematics 2017-12-06 N. Baradel , B. Bouchard , Ngoc Minh Dang

We present a method for optimal control with respect to a linear cost function for positive linear systems with coupled input constraints. We show that the optimal cost function and resulting sparse state feedback for these systems can be…

Optimization and Control · Mathematics 2023-11-07 David Ohlin , Emma Tegling , Anders Rantzer

Optimal control theory is an effective tool to improve parameter estimation of quantum systems. Different methods can be employed for the design of the control protocol. They can be based either on Quantum Fischer Information (QFI)…

Quantum Physics · Physics 2023-06-21 Quentin Ansel , Etienne Dionis , Dominique Sugny

We present a complete analysis of the laser control of a model molecular system using both optimal control theory and adiabatic techniques. This molecule has a particular potential energy surface with a bifurcating region connecting three…

Quantum Physics · Physics 2007-09-19 D. Sugny , C. Kontz , M. Ndong , G. Dive , M. Desouter-Lecomte

We develop and analyze a mathematical model of oncolytic virotherapy in the treatment of melanoma. We begin with a special, local case of the model, in which we consider the dynamics of the tumour cells in the presence of an oncolytic virus…

Dynamical Systems · Mathematics 2023-09-07 Tedi Ramaj , Xingfu Zou

The paper puts forward sufficient conditions for local controllability of a control dynamical system. The results obtained are meaningful in the case when the linear approximation to this system is not completely controllable. As a…

Optimization and Control · Mathematics 2017-09-05 E. R. Avakov , G. G. Magaril-Il'yaev

Optimal control theory is a promising candidate for a drastic improvement of the performance of quantum information tasks. We explore its ultimate limit in paradigmatic cases, and demonstrate that it coincides with the maximum speed limit…

We consider a class of closed loop stochastic optimal control problems in finite time horizon, in which the cost is an expectation conditional on the event that the process has not exited a given bounded domain. An important difficulty is…

Optimization and Control · Mathematics 2019-12-19 Yves Achdou , Mathieu Laurière , Pierre-Louis Lions

An optimal control problem with a time-parameter is considered. The functional to be optimized includes the maximum over time-horizon reached by a function of the state variable, and so an $L^\infty$-term. In addition to the classical…

Optimization and Control · Mathematics 2018-11-01 Sébastien Court , Karl Kunisch , Laurent Pfeiffer

In this paper we consider a parabolic optimal control problem with a Dirac type control with moving point source in two space dimensions. We discretize the problem with piecewise constant functions in time and continuous piecewise linear…

Numerical Analysis · Mathematics 2018-08-17 Dmitriy Leykekhman , Boris Vexler

In this paper we study optimal control problems for nonholonomic systems defined on Lie algebroids by using quasi-velocities. We consider both kinematic, i.e. systems whose cost functional depends only on position and velocities, and…

Optimization and Control · Mathematics 2015-05-27 L. Abrunheiro , M. Camarinha , J. F. Cariñena , J. Clemente-Gallardo , E. Martínez , P. Santos
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