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This paper is concerned with programming adaptive linear neural networks (ALNNs) using chemical reaction networks (CRNs) equipped with mass-action kinetics. Through individually programming the forward propagation and the backpropagation of…

Dynamical Systems · Mathematics 2022-04-14 Yuzhen Fan , Xiaoyu Zhang , Chuanhou Gao

Neural networks (NN) have been successfully applied to approximate various types of complex control laws, resulting in low-complexity NN-based controllers that are fast to evaluate. However, when approximating control laws using NN,…

Systems and Control · Electrical Eng. & Systems 2025-04-16 Dieter Teichrib , Moritz Schulze Darup

We abstract and study \emph{reachability preservers}, a graph-theoretic primitive that has been implicit in prior work on network design. Given a directed graph $G = (V, E)$ and a set of \emph{demand pairs} $P \subseteq V \times V$, a…

Data Structures and Algorithms · Computer Science 2023-11-23 Amir Abboud , Greg Bodwin

Important data mining problems such as nearest-neighbor search and clustering admit theoretical guarantees when restricted to objects embedded in a metric space. Graphs are ubiquitous, and clustering and classification over graphs arise in…

Combinatorics · Mathematics 2018-01-16 Jose Bento , Stratis Ioannidis

Chip-firing and rotor-routing are two well-studied examples of abelian networks. We study the complexity of their respective reachability problems. We show that the rotor-routing reachability problem is decidable in polynomial time, and we…

Combinatorics · Mathematics 2022-03-31 Lilla Tóthmérész

Local reasoning about programs that combine aliasing and mutable state is a longstanding challenge. Existing approaches -- ownership systems, linear and affine types, uniqueness types, and lexical effect tracking -- impose global…

Programming Languages · Computer Science 2025-09-01 Haotian Deng , Siyuan He , Songlin Jia , Yuyan Bao , Tiark Rompf

Time-limited states characterise many dynamical processes on networks: disease infected individuals recover after some time, people forget news spreading on social networks, or passengers may not wait forever for a connection. These…

Physics and Society · Physics 2023-06-13 Arash Badie-Modiri , Márton Karsai , Mikko Kivelä

Chemical reaction networks (CRNs) model the behavior of chemical reactions in well-mixed solutions and they can be designed to perform computations. In this tutorial we give an overview of various computational models for CRNs. Moreover, we…

Emerging Technologies · Computer Science 2018-11-27 Robert Brijder

There has been an increasing interest in using neural networks in closed-loop control systems to improve performance and reduce computational costs for on-line implementation. However, providing safety and stability guarantees for these…

Systems and Control · Electrical Eng. & Systems 2020-04-20 Haimin Hu , Mahyar Fazlyab , Manfred Morari , George J. Pappas

We introduce a new threshold model of social networks, in which the nodes influenced by their neighbours can adopt one out of several alternatives. We characterize social networks for which adoption of a product by the whole network is…

Social and Information Networks · Computer Science 2015-03-20 Krzysztof R. Apt , Evangelos Markakis

Recent research into analog computing has introduced new notions of computing real numbers. Huang, Klinge, Lathrop, Li, and Lutz defined a notion of computing real numbers in real-time with chemical reaction networks (CRNs), introducing the…

Emerging Technologies · Computer Science 2021-09-08 Willem Fletcher , Titus H. Klinge , James I. Lathrop , Dawn A. Nye , Matthew Rayman

A fundamental question in systems biology is what combinations of mean and variance of the species present in a stochastic biochemical reaction network are attainable by perturbing the system with an external signal. To address this…

Systems and Control · Computer Science 2017-05-02 Francesca Parise , Maria Elena Valcher , John Lygeros

In this paper a novel computational technique for finite discrete approximation of continuous dynamical systems suitable for a significant class of biochemical dynamical systems is introduced. The method is parameterized in order to affect…

Systems and Control · Computer Science 2011-08-01 Lubos Brim , Jana Fabrikova , Sven Drazan , David Safranek

The concept of the limiting step is extended to the asymptotology of multiscale reaction networks. Complete theory for linear networks with well separated reaction rate constants is developed. We present algorithms for explicit…

Chemical Physics · Physics 2010-06-15 A. N. Gorban , O. Radulescu , A. Y. Zinovyev

This paper analyses of a stochastic model of a chemical reaction network with three types of chemical species ${\cal R}$, ${\cal M}$ and ${\cal U}$ that interact to transform a flow of external resources, the chemical species ${\cal Q}$, to…

Probability · Mathematics 2025-12-01 Vincent Fromion , Philippe Robert , Jana Zaherddine

We develop a unified framework for rotor-routing that extends the classical model to a broad class of multigraphs equipped with Generalized Rotor Mechanisms (GRM). This perspective places rotor-routing on the same footing as abelian…

Discrete Mathematics · Computer Science 2025-11-24 David Auger , Pierre Coucheney , Kossi Roland Etse

This paper proves the NP-completeness of the reachability problem for the class of flat counter machines with difference bounds and, more generally, octagonal relations, labeling the transitions on the loops. The proof is based on the fact…

Computational Complexity · Computer Science 2016-02-16 Marius Bozga , Radu Iosif , Filip Konecny

Neural networks have recently become popular for a wide variety of uses, but have seen limited application in safety-critical domains such as robotics near and around humans. This is because it remains an open challenge to train a neural…

Machine Learning · Computer Science 2021-07-19 Long Kiu Chung , Adam Dai , Derek Knowles , Shreyas Kousik , Grace X. Gao

In this work, we introduce a notion of reachability entropy to characterize the smallest data rate which is sufficient enough to enforce reach-while-stay specification. We also define data rates of coder-controllers that can enforce this…

Optimization and Control · Mathematics 2022-06-22 Mahendra Singh Tomar , Majid Zamani

A Boolean control network (BCN) is a discrete-time dynamical system whose variables take values from a binary set $\{0,1\}$. At each time step, each variable of the BCN updates its value simultaneously according to a Boolean function which…

Systems and Control · Computer Science 2019-07-23 Qunxi Zhu , Zuguang Gao , Yang Liu , Weihua Gui