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Lensless in-line holography is a simple, portable, and cost-effective method of imaging especially for the biomedical microscopy applications. We propose a multiplicative gradient descent optimization based method to obtain multi-depth…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

Single-beam scanning microscopy (SBSM) is one of the most robust strategies for commercial optical systems. Although structured illumination combined with Fourier-domain spatial spectrum fusion can enhance SBSM resolution beyond the…

Optics · Physics 2025-07-15 Yongtao Liu , Tianxiao Wu , Xiao Zhou , Fan Wang

Image Phase Alignment Super-sampling (ImPASS) is a computational method for combining displaced low-resolution images into a single high-resolution image. The general steps include measuring the relative displacements, up-sampling, aligning…

Optics · Physics 2026-01-09 James N. Caron

We present a blind multiframe image-deconvolution method based on robust statistics. The usual shortcomings of iterative optimization of the likelihood function are alleviated by minimizing the M-scale of the residuals, which achieves more…

Instrumentation and Methods for Astrophysics · Physics 2017-11-09 Matthias Lee , Tamas Budavari , Richard White , Charles Gulian

Compressed Sensing MRI reconstructs images of the body's internal anatomy from undersampled measurements, thereby reducing scan time. Recently, deep learning has shown great potential for reconstructing high-fidelity images from highly…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Armeet Singh Jatyani , Jiayun Wang , Aditi Chandrashekar , Zihui Wu , Miguel Liu-Schiaffini , Bahareh Tolooshams , Anima Anandkumar

We propose a deconvolution algorithm for images blurred and degraded by a Poisson noise. The algorithm uses a fast proximal backward-forward splitting iteration. This iteration minimizes an energy which combines a \textit{non-linear} data…

Applications · Statistics 2008-12-18 François-Xavier Dupé , Jalal Fadili , Jean Luc Starck

Reconstructing and understanding 3D structures from a limited number of images is a well-established problem in computer vision. Traditional methods usually break this task into multiple subtasks, each requiring complex transformations…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Zhiwen Fan , Jian Zhang , Wenyan Cong , Peihao Wang , Renjie Li , Kairun Wen , Shijie Zhou , Achuta Kadambi , Zhangyang Wang , Danfei Xu , Boris Ivanovic , Marco Pavone , Yue Wang

Incoherent imaging, including fluorescence and absorption microscopy, is often limited by weak signals and resolution constraints -- notoriously, Rayleigh's curse. We investigate how spatially structured quantum probes, combined with…

Quantum Physics · Physics 2025-10-13 Anthony J. Brady , Zihao Gong , Alexey V. Gorshkov , Saikat Guha

Fluorescence microscopy is essential to study biological structures and dynamics. However, existing systems suffer from a tradeoff between field-of-view (FOV), resolution, and complexity, and thus cannot fulfill the emerging need of…

Optics · Physics 2022-09-09 Yujia Xue , Qianwan Yang , Guorong Hu , Kehan Guo , Lei Tian

The analysis of spatial data from biological imaging technology, such as imaging mass spectrometry (IMS) or imaging mass cytometry (IMC), is challenging because of a competitive sampling process which convolves signals from molecules in a…

Machine Learning · Statistics 2025-09-26 Joaquim Valerio Teixeira , Ed Reznik , Sudpito Banerjee , Wesley Tansey

Increasing the resolution of image sensors has been a never ending struggle since many years. In this paper, we propose a novel image sensor layout which allows for the acquisition of images at a higher resolution and improved quality. For…

Image and Video Processing · Electrical Eng. & Systems 2022-04-28 Jürgen Seiler , Markus Jonscher , Thomas Ussmueller , André Kaup

Multi-scale deconvolution is an ill-posed inverse problem in imaging, with applications ranging from microscopy, through medical imaging, to astronomical remote sensing. In the case of high-energy space telescopes, multi-scale deconvolution…

Instrumentation and Methods for Astrophysics · Physics 2023-03-30 Anna Volpara , Michele Piana , Anna Maria Massone

This paper presents a Multispectral imaging (MSI) approach that combines the use of a diffractive optical element, and a deep learning algorithm for spectral reconstruction. Traditional MSI techniques often face challenges such as high…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Khen Cohen , Tuval Kay

By exploiting the nonlinear responses of the fluorescent probes, the spatial resolution of structured illumination microscopy(SIM) can be further increased. However, due to the complex reconstruction process, the traditional reconstruction…

Readout multiplexing is a promising solution to overcome hardware limitations and data bottlenecks in imaging with single-photon detectors. Conventional multiplexed readout processing creates an upper bound on photon counts at a very fine…

Quantum Physics · Physics 2026-03-12 Shashwath Bharadwaj , Ruangrawee Kitichotkul , Akshay Agarwal , Vivek K Goyal

Confocal microscopy has long been a cornerstone technique for visualizing complex interactions and processes within cellular structures. However, achieving super-resolution imaging of multiple organelles and their interactions…

Optics · Physics 2025-08-19 Qinglin Chen , Luwei Wang , Jia Li , Dan Shao , Xiaoyu Weng , Liwei Liu , Dayong Jin , Junle Qu

A simple, yet general, formalism for the optimized linear combination of astrophysical images is constructed and demonstrated. The formalism allows the user to combine multiple undersampled images to provide oversampled output at high…

Instrumentation and Methods for Astrophysics · Physics 2015-05-28 Barnaby Rowe , Christopher Hirata , Jason Rhodes

We present a novel deep learning approach to reconstruct confocal microscopy stacks from single light field images. To perform the reconstruction, we introduce the LFMNet, a novel neural network architecture inspired by the U-Net design. It…

Image and Video Processing · Electrical Eng. & Systems 2020-03-25 Josue Page , Federico Saltarin , Yury Belyaev , Ruth Lyck , Paolo Favaro

Single-pixel imaging (SPI) is a novel imaging technique whose working principle is based on the compressive sensing (CS) theory. In SPI, data is obtained through a series of compressive measurements and the corresponding image is…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Stephen L. H. Lau , Edwin K. P. Chong

Image deblurring aims to restore the detailed texture information or structures from blurry images, which has become an indispensable step in many computer vision tasks. Although various methods have been proposed to deal with the image…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Yanni Zhang , Qiang Li , Miao Qi , Di Liu , Jun Kong , Jianzhong Wang