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The development of neurologically active drugs faces a challenge in treating brain diseases due to the blood-brain barrier's impermeability. High-intensity focused ultrasound can open the barrier in a targeted manner, expanding treatment…

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

Medical Physics · Physics 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

Bubble-driven inertial pumps are a novel method of moving liquids through microchannels. We combine high-speed imaging, computational fluid dynamics (CFD) simulations and an effective one-dimensional model to study the fundamentals of…

Fluid Dynamics · Physics 2016-05-17 A. N. Govyadinov , P. E. Kornilovitch , D. P. Markel , E. D. Torniainen

We present a novel experiment on interfacial wave dynamics in orbitally shaken cylindrical vessels containing two- and three fluid layers. The experiment was designed as a hydrodynamical model for both alu- minum reduction cells and liquid…

Fluid Dynamics · Physics 2018-08-01 Gerrit Maik Horstmann , Markus Wylega , Tom Weier

We numerically investigate bouncing and non-bouncing of droplets during isothermal impact on superhydrophobic surfaces. An in-house, experimentally-validated, finite-element method based computational model is employed to simulate the…

Fluid Dynamics · Physics 2016-01-06 Prathamesh G. Bange , Rajneesh Bhardwaj

Heat enhancement at the target in a High Intensity Focused Ultrasound (HIFU) field is investigated by considering the effects of the injection of microbubbles in the vicinity of the tumor to be ablated. The interaction between the bubble…

Fluid Dynamics · Physics 2025-11-27 Aswin Gnanaskandan , Chao-Tsung Hsiao , Georges Chahine

Ultrasonic irradiation of liquids, such as water-alcohol solutions, results in cavitation or the formation of small bubbles. Cavitation bubbles are generated in real solutions without the use of optical traps making our system as close to…

While the ultrasound and cavitation based therapies have mushroomed over the years, there is a lack of online monitoring the cavitation bubble dynamics in biological tissue. {\color{black}Here we demonstrate that with ultrasonic plane wave…

Fluid Dynamics · Physics 2023-05-26 S. Izak Ghasemian , F. Reuter , C. D. Ohl

Acoustic droplet vaporization denotes the phase-change of micron- and sub-micron-sized droplets upon the application of high-amplitude ultrasound. The asymmetric collapse of the incepted vapor bubbles within the droplets can give rise to…

Fluid Dynamics · Physics 2026-05-11 Anunay Prasanna , Samuele Fiorini , Gazendra Shakya , Outi Supponen

The influence of initial shape imperfections on the post-buckling and translational behavior of encapsulated microbubbles is investigated subject to acoustic excitation in an unbounded flow. Bifurcation analysis reveals that imperfections…

Fluid Dynamics · Physics 2025-08-26 Maria Vlachomitrou , Georges Chabouh , Alkmini Lytra , Nikos Pelekasis

Pressure changes travel at an infinite sound speed in an incompressible ideal fluid, opposite to what happens in a bubbly liquid, where the presence of bubbles adds compressibility such that the sound speed becomes finite. Here, the…

Fluid Dynamics · Physics 2024-05-13 Edgar Ortega-Roano , Devaraj van der Meer

We present experimental investigations of antibubbles. Such an unusual fluid object is a thin spherical air shell surrounding a liquid globule. We explain how to produce them and we study their stability. By overweighting antibubbles with a…

Soft Condensed Matter · Physics 2007-05-23 S. Dorbolo , N. Vandewalle

Advances in intensity-based microscopy techniques have improved our ability to quantify particle motion at microscopic scales, enabling insight into diffusion and collective dynamics. Building on this foundation, we introduce a novel…

Soft Condensed Matter · Physics 2026-04-03 Sophie Hermann , Seyed Saman Banarooei , Adam Carter , Carlos A. Silvera Batista , Sophie Marbach

OBJECTIVE: Assessing the biomechanical behaviour of the aortic wall in vivo can potentially improve the diagnosis and prognosis of patients with abdominal aortic aneurysms (AAA). With ultrasound, AAA wall stiffness can be estimated as the…

Gas-liquid flows through packed bed reactors (PBRs) are challenging to predict due to the tortuous flow paths that fluid interfaces must traverse. Experiments at the International Space Station showed that bubble and pulse flows are…

Fluid Dynamics · Physics 2024-03-21 Pranay P. Nagrani , Amy M. Marconnet , Ivan C. Christov

Gaseous microemboli (GME) introduced during cardiac surgery are considered as a potential source of morbidity, which has driven the development of the first bubble counters. Two new generation bubble counters claim correct sizing and…

We study nonlinear dynamics in a model of three interacting encapsulated gas bubbles in a liquid. The model is a system of three coupled nonlinear oscillators with an external periodic force. Such bubbles have numerous applications, for…

Dynamical Systems · Mathematics 2024-05-17 Ivan Garashchuk , Alexey Kazakov , Dmitry Sinelshchikov

Inertial pumping is a promising new method of moving fluids through microchannels but many of its properties remain unexplored. In this work, inertial flow rates are investigated for different channel lengths, operating temperatures, and…

Fluid Dynamics · Physics 2022-02-03 Pavel E. Kornilovitch , Tyler Cochell , Alexander N. Govyadinov

The effect of charge on the dynamics of a gas bubble undergoing forced oscillations in a liquid due to incidence of an ultrasonic wave is theoretically investigated. The limiting values of the possible charge a bubble may physically carry…

Chaotic Dynamics · Physics 2015-06-15 Thotreithem Hongray , B. Ashok , J. Balakrishnan

Monodisperse lipid-coated microbubbles are a promising route to unlock the full potential of ultrasound contrast agents for medical diagnosis and therapy. Here, we present a stand-alone lab-on-a-chip instrument that allows microbubbles to…