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The inherent instability of oscillatory flows presents a significant challenge in microfluidics, impairing performance in different applications from particle detachemnt to organs-on-a-chip. Trapped air inside a microfluidic system…

Fluid Dynamics · Physics 2025-11-04 Andreu Benavent-Claró

The formation and evolution of immersed surface micro- and nanobubbles are essential in various practical applications, such as the usage of superhydrophobic rematerials, drug delivery, and mineral flotation. In this work, we investigate…

Accurate measurement of dynamic contact angles in aqueous environments is essential for evaluating surface wettability. However, conventional captive bubble methods often suffer from limitations such as bubble instability and interference…

Soft Condensed Matter · Physics 2026-05-13 Koki Iwasaki , Hiroyuki Ebata , Hiroaki Katsuragi

The spherical dynamics of a bubble in a compressible liquid has been studied extensively since the early work of Gilmore. Numerical codes to study the behavior, including when large non-spherical deformations are involved, have since been…

Fluid Dynamics · Physics 2015-03-17 Arvind Jayaprakash , Sowmitra Singh , Georges Chahine

In bubble-assisted Liquid HoleMultipliers(LHM), developed for noble-liquid radiation detectors, the stability of the bubble and the electro-mechanical properties of the liquid-to-gas interface play a dominant role in the detector…

Instrumentation and Detectors · Physics 2021-09-22 A. Tesi , E. Segre , S. Leardini , A. Breskin , S. Kapishnikov , L. Moleri , D. Vartsky , S. Bressler

We describe an experimental setup specifically designed for measuring the ultrasonic transmission through liquid foams, over a broad range of frequencies (60-600 kHz). The question of determining the ultrasonic properties of the foam…

Classical Physics · Physics 2012-11-21 Juliette Pierre , F. Elias , Valentin Leroy

Bubble curtains are widely used for sound mitigation during offshore pile driving to protect marine life. However, the lack of well validated hydrodynamic models is a major factor in the inability to predict the sound attenuation of a…

Fluid Dynamics · Physics 2024-01-19 Simon Beelen , Dominik Krug

The importance of the excitation bandwidth is well known in diagnostic ultrasound imaging. However, the effect of excitation bandwidth in therapeutic applications of microbubbles has been mostly overlooked. A majority of contrast agent…

Medical Physics · Physics 2019-02-06 Sevan Harput , James McLaughlan , David M. J. Cowell , Steven Freear

In a microfluidic environment, the presence of bubbles is often detrimental to the functionality of the device, leading to clogging or cavitation, but microbubbles can also be an indispensable asset in other applications such as…

A variety of approaches have been used to model the dynamics of a single, isolated bubble nucleated by a microsecond length high-amplitude ultrasound pulse (e.g., a histotripsy pulse). Until recently, the lack of single--bubble experimental…

Fluid Dynamics · Physics 2020-12-02 Lauren Mancia , Mauro Rodriguez , Jonathan Sukovich , Zhen Xu , Eric Johnsen

The mechanical properties of biological fluids can serve as early indicators of disease, offering valuable insights into complex physiological and pathological processes. However, the existing technologies can hardly support high throughput…

Optics · Physics 2025-09-18 Zhonghao Li , Zhihan Cai , Chaoyang Gong

The micromixing process in microfluidic devices is of central importance in quite a few applications, with microfluidic studies on carbon capture and environmental monitoring being two examples. High surface area to volume ratio in…

Fluid Dynamics · Physics 2025-11-21 Seyed Shahriar Riazi , Seyed Mostafa Hosseinalipour

Acoustic characterization of ultrasound contrast agents (UCAs, coated microbubbles) relies on the attenuation theory that assumes the UCAs oscillate linearly at sufficiently low excitation pressures. Effective shell parameters of the UCAs…

Fluid Dynamics · Physics 2020-04-23 Lang Xia

The local beat-to-beat local pulse pressure (PP) and blood pressure waveform of arteries, especially central arteries, are important indicators of the course of cardiovascular diseases (CVDs). Nevertheless, noninvasive measurement of them…

Signal Processing · Electrical Eng. & Systems 2023-05-30 Lirui Xu , Pang Wu , Pan Xia , Fanglin Geng , Peng Wang , Xianxiang Chen , Zhenfeng Li , Lidong Du , Shuping Liu , Li Li , Hongbo Chang , Zhen Fang

To further understand their nature, micro cavitation bubbles were systematically diffused around the exterior of a test body (tube) fully submerged in a water tank. The primary purpose was to assess the feasibility of applying micro…

Fluid Dynamics · Physics 2017-11-09 Stefan C. Mancas , Shahrdad G. Sajjadi , Asalie Anderson , Derek Hoffman

The scattering of ultrasound from bubbles of micrometer-sized radius, such as used in contrast enhancers for ultrasound diagnostics, is studied. We show that sound scattering and ``active'' emission of sound from oscillating bubbles are not…

Soft Condensed Matter · Physics 2009-10-31 Sascha Hilgenfeldt , Detlef Lohse , Michael Zomack

Understanding the ultrasound pressure-driven dynamics of microbubbles confined in viscoelastic materials is relevant for multiple biomedical applications, ranging from contrast-enhanced ultrasound imaging to ultrasound-assisted drug…

Ultrasound-driven microbubbles rectify oscillatory motion into strong steady streaming flow [1, 2]. In this fluid dynamics video, we show size-dependent trapping, focusing and sorting of microparticles, utilizing the interaction between…

Fluid Dynamics · Physics 2010-10-19 Cheng Wang , Shreyas Jalikop , Sascha Hilgenfeldt

Ultrasound-driven microbubbles are increasingly being investigated for both molecular imaging and therapeutic applications. To be effective, these bubbles must be brought into close proximity or direct contact with the target site.…

Fluid Dynamics · Physics 2026-02-10 Marco Cattaneo , Outi Supponen

Correct measurement of the shell properties of coated microbubbles (MBs) is essential to understanding and optimizing their response to ultrasound (US) exposure parameters in diagnostic and therapeutic ultrasound. MBs are surrounded by…