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In the recent years, we witness a great interest in imaging, in a wide sense, using contrast agents. One of the reasons is that many imaging modalities, as the ones related to medical sciences, suffer from several shortcomings. The most…

Optics · Physics 2020-08-28 Ahcene Ghandriche , Mourad Sini

Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…

Medical Physics · Physics 2022-10-17 Xiaoxiao Zhao , Carly Pellow , David E. Goertz

Acoustic microstreaming has several industrial, therapeutic, and biomedical applications - Acoustic cleaning, micromixing, microfluid transport, hemolysis, sonoporation. The acoustic microstreaming due to the oscillation of ultrasound…

Fluid Dynamics · Physics 2022-01-19 Nima Mobadersany

We study the time-domain acoustic wave propagation in the presence of a micro-bubble. This micro-bubble is characterized by a mass density and bulk modulus which are both very small as compared to the ones of the background vacuum. The goal…

Analysis of PDEs · Mathematics 2023-12-13 Arpan Mukherjee , Mourad Sini

The nonlinear dynamic behaviour of microscopic bubbles near a wall is investigated. The Keller-Miksis-Parlitz equation is adopted, but modified to account for the presence of the wall. This base model describes the time evolution of the…

Fluid Dynamics · Physics 2012-06-14 Sergey A. Suslov , Andrew Ooi , Richard Manasseh

Results of the measurements of sound speed and attenuation in a bubbly medium are reported. Monodisperse bubble solutions are sonicated with broadband ultrasound pulses with pressure amplitudes ranging between 12.5-100 kPa. Fundamental…

Fluid Dynamics · Physics 2018-11-20 A. J. Sojahrood , Q. Li , H. Haghi , R. Karshafian , T. M. Porter , M. C. Kolios

Regular blood pressure (BP) monitoring in clinical and ambulatory settings plays a crucial role in the prevention, diagnosis, treatment, and management of cardiovascular diseases. Recently, the widespread adoption of ambulatory BP…

Medical Physics · Physics 2023-12-19 Seyedeh Somayyeh Mousavi , Matthew A. Reyna , Gari D. Clifford , Reza Sameni

Reliable communication in confined environments, such as blood vessels or industrial pipelines, remain challenging due to signal attenuation and limited sensor accessibility. Therefore, this work investigates microbubbles as robust…

Signal Processing · Electrical Eng. & Systems 2026-04-17 Annika Tjabben , Carolin Conrad , Hans D. Schotten

Ultrasound-matter interactions underpin numerous biomedical and soft-matter applications, yet simulating these phenomena is challenging due to the large separation of viscous and sonic time scales. Continuum methods capture large-scale wave…

Soft Condensed Matter · Physics 2026-02-18 Urban Čoko , Tilen Potisk , Matej Praprotnik

The acoustic nonlinearity parameter B/A plays a significant role in the characterization of acoustic properties of various biomaterials and biological tissues. It has the potential to be a favorable imaging modality in contrast ultrasound…

Fluid Dynamics · Physics 2019-08-16 Lang Xia

The pursuit of targeted therapies capable of overcoming biological barriers, including the tenacious blood-brain barrier, has spurred the investigation into stimuli-responsive microagents. This approach could improve therapeutic efficacy,…

Bubbles in complex fluids are often desirable, and sometimes simply inevitable, in the processing of formulated products. Bubbles can rise by buoyancy, grow or dissolve by mass transfer, and readily respond to changes in pressure, thereby…

Fluid Dynamics · Physics 2020-11-02 Brice Saint-Michel , Valeria Garbin

Understanding how substrate-attached bubbles respond to ultrasound is important for applications from industrial cleaning to biomedical therapy. Under ultrasonic excitation, bubbles can deform through Faraday instability and periodically…

Ultrasound contrast agents have been recently utilized in therapeutical implementations for targeted delivery of pharmaceutical substances. Radial pulsations of a cluster of encapsulated microbubbles under the action of an ultrasound field…

Fluid Dynamics · Physics 2018-11-19 S. Behniaa , M. Yahyavi , R. Habibpourbisafar , F. Mottaghi

Ultrasound contrast agents comprise gas microbubbles surrounded by stabilising elastic or viscoelastic shells. Microbubbles containing liquid or solid cores are referred to as antibubbles. The manufacturing process of long-lived antibubbles…

An increasing number of research topics and applications ask for a precise measurement of the size distribution of small bubbles in a liquid - and hence for reliable and automated image analysis. However, due to the strong mismatch between…

Soft Condensed Matter · Physics 2016-11-24 Thibaut Gaillard , Clément Honorez , Maxime Jumeau , Florence Elias , Wiebke Drenckhan

We report experimental observations of the volume acoustic modes of air bubbles in water, including both the fundamental Minnaert breathing mode and a family of higher-order modes extending into the megahertz frequency range. Bubbles were…

Fluid Dynamics · Physics 2024-05-03 K. G. Scheuer , F. B. Romero , R. G. DeCorby

Yield-stress fluids naturally trap small bubbles when their buoyancy applies an insufficient stress to induce local yielding of the material. Under acoustic excitation, trapped bubbles can be driven into volumetric oscillations and apply an…

Soft Condensed Matter · Physics 2020-11-02 Brice Saint-Michel , Valeria Garbin

High-throughput label-free measurements of the optical and mechanical properties of single microparticles play an important role in biological research, drug development, and related large population assays. Mechanical detection techniques…

Instrumentation and Detectors · Physics 2018-12-05 Kewen Han , Jeewon Suh , Gaurav Bahl

Sensors based on whispering gallery resonators have minute footprints and can push achievable sensitivities and resolutions to their limits. Here, we use a microbubble resonator, with a wall thickness of 500 nm and an intrinsic Q-factor of…

Optics · Physics 2016-01-08 Yong Yang , Sunny Saurabh , Jonathan M Ward , Síle Nic Chormaic