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Interactive molecular graphics applications facilitate analysis of three dimensional protein structures. Naturally, non-interactive 2-D snapshots of the protein structures do not convey the same level of geometric detail. Several 2-D…

Quantitative Methods · Quantitative Biology 2014-02-24 Francis Bell , Chunyu Zhao , Ahmet Sacan

In recent years, multiplexed Fluorescence In Situ Hybridization (FISH) or FISH-omics methods have rapidly expanded, enabling the quantification of chromatin organization in single cells, often in conjunction with measurements of RNA and…

Understanding chromatin dynamics across multiple spatiotemporal scales requires models that reconcile biological specificity with physics-based interactions and computational tractability. We present a modular, recognition-enabled…

Biological Physics · Physics 2025-12-04 Hesam Arabzadeh , Dmitri Kireev

Molecular visualization software has long supported research and education in chemical and structural sciences, but consumer devices constrained to 2D inputs and outputs pose two major challenges: they poorly convey 3D nature, and 3D…

Chemical Physics · Physics 2025-09-05 Luciano A. Abriata

The work is devoted to the development of an information system ISANM that will be useful for teaching students and applicable in the work of engineers and researchers for automating the analysis of colloidal structure morphology. The ISANM…

Soft Condensed Matter · Physics 2025-07-22 Ludia T. Khusainova , Konstantin S. Kolegov

While 2D occupancy maps commonly used in mobile robotics enable safe navigation in indoor environments, in order for robots to understand and interact with their environment and its inhabitants representing 3D geometry and semantic…

Robotics · Computer Science 2025-01-09 Krishnananda Prabhu Sivananda , Francesco Verdoja , Ville Kyrki

Spatial intelligence is emerging as a transformative frontier in AI, yet it remains constrained by the scarcity of large-scale 3D datasets. Unlike the abundant 2D imagery, acquiring 3D data typically requires specialized sensors and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Xingyu Miao , Haoran Duan , Quanhao Qian , Jiuniu Wang , Yang Long , Ling Shao , Deli Zhao , Ran Xu , Gongjie Zhang

The ability to precisely visualize the atomic geometry of the interactions between a drug and its protein target in structural models is critical in predicting the correct modifications in previously identified inhibitors to create more…

Biomolecules · Quantitative Biology 2018-08-14 Erick Martins Ratamero , Dom Bellini , Christopher G. Dowson , Rudolf A. Roemer

In Geographical Information search, map visualization can challenge the user because results can consist of a large set of heterogeneous items, increasing visual complexity. We propose a novel visualization model to address this issue. Our…

Human-Computer Interaction · Computer Science 2020-04-02 Liliana Ardissono , Matteo Delsanto , Maurizio Lucenteforte , Noemi Mauro , Adriano Savoca , Daniele Scanu

Protein-ligand scoring is an important step in a structure-based drug design pipeline. Selecting a correct binding pose and predicting the binding affinity of a protein-ligand complex enables effective virtual screening. Machine learning…

Machine Learning · Statistics 2020-10-19 Joshua Hochuli , Alec Helbling , Tamar Skaist , Matthew Ragoza , David Ryan Koes

A data structure and toolkit are presented here that allow for the description and manipulation of mathematical models of three-manifolds and their interactive display from multiple viewpoints via the OpenGL 3D graphics package. The data…

Computational Geometry · Computer Science 2012-01-30 Don V. Black

The representation of a Configuration Space C plays a vital role in accelerating the finding of a collision-free path for sampling-based motion planners where the majority of computation time is spent in collision checking of states.…

Robotics · Computer Science 2024-06-07 Jorge Ocampo Jimenez , Wael Suleiman

Extensively exploring protein conformational landscapes remains a major challenge in computational biology due to the high computational cost involved in dynamic physics-based simulations. In this work, we propose a novel pipeline, MoDyGAN,…

Machine Learning · Computer Science 2025-07-21 Jingbo Liang , Bruna Jacobson

Colorization is a well-explored problem in the domains of image and video processing. However, extending colorization to 3D scenes presents significant challenges. Recent Neural Radiance Field (NeRF) and Gaussian-Splatting(3DGS) methods…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Ankit Dhiman , R Srinath , Srinjay Sarkar , Lokesh R Boregowda , R Venkatesh Babu

Chromatin is a complex of DNA and specific proteins forming an intermediary level of organization of eukaryotic genomes, between double-stranded DNA and chromosome. Within a generic modeling of the chromatin assembly, we investigate the…

Statistical Mechanics · Physics 2016-08-16 Eli Ben-Haïm , Annick Lesne , Jean-Marc Victor

Owing to their intricate variable density architecture, and as a principal site of star formation, molecular clouds represent one of the most functionally significant, yet least understood features of our universe. To unravel the intrinsic…

Instrumentation and Methods for Astrophysics · Physics 2021-09-08 Nia Imara , John C. Forbes , James C. Weaver

Everybody wants to analyse their data, but only few posses the data science expertise to to this. Motivated by this observation we introduce a novel framework and system \textsc{VisualSynth} for human-machine collaboration in data science.…

Artificial Intelligence · Computer Science 2020-04-24 Clément Gautrais , Yann Dauxais , Stefano Teso , Samuel Kolb , Gust Verbruggen , Luc De Raedt

Recent advances in biological technologies, such as multi-way chromosome conformation capture (3C), require development of methods for analysis of multi-way interactions. Hypergraphs are mathematically tractable objects that can be utilized…

Quantitative Methods · Quantitative Biology 2023-07-19 Joshua Pickard , Can Chen , Rahmy Salman , Cooper Stansbury , Sion Kim , Amit Surana , Anthony Bloch , Indika Rajapakse

We introduce The Fabric of the Universe, an art and science collaboration focused on exploring the cosmic web of dark matter with unconventional techniques and materials. We discuss two of our projects in detail. First, we describe a…

Popular Physics · Physics 2017-04-26 Benedikt Diemer , Isaac Facio

We present PrestaLine: Gorynych, a comprehensive numerical tool designed to model the dynamical, chemical, and spectral evolution of collapsing molecular cores from the prestellar phase to protostellar accretion. The code integrates three…

Astrophysics of Galaxies · Physics 2026-02-16 Olga Kochina , Dmitri Wiebe , Yaroslav Pavlyuchenkov , Maria S. Kirsanova