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We test the hypothesis whether transforming a data matrix into a 3D shaded surface or even a volumetric display can be more appealing to humans than a scatterplot since it makes direct use of the innate 3D scene understanding capabilities…

Human-Computer Interaction · Computer Science 2019-11-19 Bing Wang , Klaus Mueller

When studying multi-body protein complexes, biochemists use computational tools that can suggest hundreds or thousands of their possible spatial configurations. However, it is not feasible to experimentally verify more than only a very…

Human-Computer Interaction · Computer Science 2019-09-25 Katarína Furmanová , Adam Jurčík , Barbora Kozlíková , Helwig Hauser , Jan Byška

Scanning Electron Microscopes (SEMs) are widely renowned for their ability to analyze the surface structures of microscopic objects, offering the capability to capture highly detailed, yet only grayscale, images. To create more expressive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Takuma Nishimura , Andreea Dogaru , Martin Oeggerli , Bernhard Egger

Chromatin is a highly compact and dynamic nuclear structure that consists of DNA and associated proteins. The main organizational unit is the nucleosome, which consists of a histone octamer with DNA wrapped around it. Histone proteins are…

Genomics · Quantitative Biology 2013-09-30 Veit Schwämmle , Ole Nørregaard Jensen

Software visualization seeks to represent software artifacts graphical-ly in two or three dimensions, with the goal of enhancing comprehension, anal-ysis, maintenance, and evolution of the source code. In this context, visualiza-tions…

Software Engineering · Computer Science 2025-09-30 Anthony Savidis , Christos Vasilopoulos

The 3D folding of a mammalian gene can be studied by a polymer model, where the chromatin fibre is represented by a semiflexible polymer which interacts with multivalent proteins, representing complexes of DNA-binding transcription factors…

Biological Physics · Physics 2023-12-20 Andrea Bonato , Dom Corbett , Sergey Kitaev , Davide Marenduzzo , Alexander Morozov , Enzo Orlandini

The utilization of computational photography becomes increasingly essential in the medical field. Today, imaging techniques for dermatology range from two-dimensional (2D) color imagery with a mobile device to professional clinical imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-09-06 Merlin A. Nau , Florian Schiffers , Yunhao Li , Bingjie Xu , Andreas Maier , Jack Tumblin , Marc Walton , Aggelos K. Katsaggelos , Florian Willomitzer , Oliver Cossairt

Digitizing the physical world into accurate simulation-ready virtual environments offers significant opportunities in a variety of fields such as augmented and virtual reality, gaming, and robotics. However, current 3D reconstruction and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Hongchi Xia , Chih-Hao Lin , Hao-Yu Hsu , Quentin Leboutet , Katelyn Gao , Michael Paulitsch , Benjamin Ummenhofer , Shenlong Wang

We discuss a polymer model for the 3D organization of human chromosomes. A chromosome is represented by a string of beads, with each bead being "colored" according to 1D bioinformatic data (e.g., chromatin state, histone modification, GC…

Biological Physics · Physics 2020-10-15 C. A. Brackley , D. Michieletto , F. Mouvet , J. Johnson , S. Kelly , P. R. Cook , D. Marenduzzo

Protein phosphorylation involves the reversible modification of a protein (substrate) residue by another protein (kinase). Liquid chromatography-mass spectrometry studies are rapidly generating massive protein phosphorylation datasets…

Genomic data visualization is essential for interpretation and hypothesis generation as well as a valuable aid in communicating discoveries. Visual tools bridge the gap between algorithmic approaches and the cognitive skills of…

Genomics · Quantitative Biology 2019-11-04 Sabrina Nusrat , Theresa Harbig , Nils Gehlenborg

A fundamental goal of research in molecular biology is to understand protein structure. Protein crystallography is currently the most successful method for determining the three-dimensional (3D) conformation of a protein, yet it remains…

Artificial Intelligence · Computer Science 2014-11-17 L. Leherte , J. Glasgow , K. Baxter , E. Steeg , S. Fortier

During the eukaryotic cell cycle, chromatin undergoes several conformational changes, which are believed to play key roles in gene expression regulation during interphase, and in genome replication and division during mitosis. In this…

Subcellular Processes · Quantitative Biology 2007-09-03 Julien Mozziconacci , Christophe Lavelle , Maria Barbi , Annick Lesne , Jean-Marc Victor

A recent paper on visualizing the sensitivity of hadronic experiments to nucleon structure [1] introduces the tool PDFSense which defines measures to allow the user to judge the sensitivity of PDF fits to a given experiment. The sensitivity…

High Energy Physics - Phenomenology · Physics 2018-10-17 Dianne Cook , Ursula Laa , German Valencia

Most modern solar observatories deliver data products formatted as 3D spatio-temporal data cubes, that contain additional, higher dimensions with spectral and/or polarimetric information. This multi-dimensional complexity presents a major…

Instrumentation and Methods for Astrophysics · Physics 2022-08-02 Malcolm K. Druett , Alexander G. M. Pietrow , Gregal J. M. Vissers , Carolina Robustini , Flavio Calvo

Though the mediums for visualization are limited, the potential dimensions of a dataset are not. In many areas of scientific study, understanding the correlations between those dimensions and their uncertainties is pivotal to mining useful…

Astrophysics · Physics 2009-02-25 Steve Haroz , Kwan-Liu Ma , Katrin Heitmann

During medicine studies, visualization of certain elements is common and indispensable in order to get more information about the way they work. Currently, we resort to the use of photographs -which are insufficient due to being static- or…

Graphics · Computer Science 2016-07-21 Juan Perozo , Mimia Lo Leung , Esmitt Ramírez

DataViz3D is an innovative online software that transforms complex datasets into interactive 3D spatial models using holographic technology. This tool enables users to generate scatter plot within a 3D space, accurately mapped to the XYZ…

Computer Vision and Pattern Recognition · Computer Science 2024-01-22 Jinli Duan

Cosmic shear is one of the primary probes to test gravity with current and future surveys. There are two main techniques to analyse a cosmic shear survey; a tomographic method, where correlations between the lensing signal in different…

Cosmology and Nongalactic Astrophysics · Physics 2018-11-14 A. Spurio Mancini , R. Reischke , V. Pettorino , B. M. Schäfer , M. Zumalacárregui

For the Bio+Med-Vis Challenge 2024, we propose a visual analytics system as a redesign for the scatter pie chart visualization of cell type proportions of spatial transcriptomics data. Our design uses three linked views: a view of the…

Human-Computer Interaction · Computer Science 2024-09-12 David Hägele , Yuxuan Tang , Daniel Weiskopf