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High-resolution optical microscopy has transformed biological imaging, yet its resolution and contrast deteriorate with depth due to multiple light scattering. Conventional correction strategies typically approximate the medium as one or a…

Biomedical applications requiring tissue diagnosis, activation, and treatment could be substantially leveraged by optical methods, owing to their unique feature set. However, their widespread application is severely limited by the strong…

Optics · Physics 2019-10-23 Maxim Cherkashin , Carsten Brenner , Georg Schmitz , Martin Hofmann

Focusing waves inside inhomogeneous media is a fundamental problem for imaging. Spatial variations of wave velocity can strongly distort propagating wavefronts and degrade image quality. Adaptive focusing can compensate for such aberration,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 William Lambert , Laura A. Cobus , Thomas Frappart , Mathias Fink , Alexandre Aubry

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

Optical microscopy offers a unique insight of biological structures with a sub-micrometer resolution and a minimum invasiveness. However, the inhomogeneities of the specimen itself can induce multiple scattering of light and optical…

Deep-tissue optical imaging suffers from the reduction of resolving power due to tissue-induced optical aberrations and multiple scattering noise. Reflection matrix approaches recording the maps of backscattered waves for all the possible…

We present a physically intuitive matrix approach for wave imaging and characterization in scattering media. The experimental proof-of-concept is performed with ultrasonic waves, but this approach can be applied to any field of wave physics…

Applied Physics · Physics 2020-07-01 William Lambert , Laura A. Cobus , Mathieu Couade , Mathias Fink , Alexandre Aubry

The acoustic inverse obstacle scattering problem consists of determining the shape of a domain from measurements of the scattered far field due to some set of incident fields (probes). For a penetrable object with known sound speed, this…

Numerical Analysis · Mathematics 2023-02-15 Carlos Borges , Manas Rachh , Leslie Greengard

Acousto-optic imaging (AOI) enables optical-contrast imaging deep inside scattering samples via localized ultrasound-modulation of scattered light. While AOI allows optical investigations at depths, its imaging resolution is inherently…

Optics · Physics 2021-01-26 Moriya Rosenfeld , Daniel Doktofsky , Gil Weinberg , Yunzhe Li , Lei Tian , Ori Katz

On-invasive optical imaging techniques are essential diagnostic tools in many fields. Although various recent methods have been proposed to utilize and control light in multiple scattering media, non-invasive optical imaging through and…

Recently, 3D Gaussian Splatting (3DGS) has enabled photorealistic view synthesis at high inference speeds. However, its splatting-based rendering model makes several approximations to the rendering equation, reducing physical accuracy. We…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Chinmay Talegaonkar , Yash Belhe , Ravi Ramamoorthi , Nicholas Antipa

Imaging with optical resolution through highly scattering media is a long sought-after goal with important applications in deep tissue imaging. Although being the focus of numerous works, this goal was considered impractical until recently.…

Optics · Physics 2012-02-10 Ori Katz , Eran Small , Yaron Silberberg

Optoacoustic image formation is conventionally based upon ultrasound time-of-flight readings from multiple detection positions. Herein, we exploit acoustic scattering to physically encode the position of optical absorbers in the acquired…

Biological Physics · Physics 2019-10-30 Xose Luis Dean-Ben , Ali Ozbek , Hernan Lopez-Schier , Daniel Razansky

In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident…

Just as turbulence in the Earth's atmosphere can severely limit the angular resolution of optical telescopes, turbulence in the ionized interstellar medium fundamentally limits the resolution of radio telescopes. We present a scattering…

Instrumentation and Methods for Astrophysics · Physics 2016-12-14 Michael D. Johnson

Holographic optical coherence tomography (OCT) is a powerful imaging technique, but its ability to reveal low-reflectivity features is limited. In this study, we performed holographic OCT by incoherently averaging volumes with changing…

Full-field imaging through scattering media is fraught with many challenges. Despite many achievements in recent years, current imaging methods are too slow to deal with fast dynamics that occur for example in biomedical imaging. Here we…

Diffuse Optical Tomography (DOT) is a reliable and widespread technique for monitoring qualitative changes in absorption inside highly scattering media. It has been shown, however, that Acousto-Optic (AO) imaging can provide significantly…

Recording and identifying faint objects through atmospheric scattering media by an optical system are fundamentally interesting and technologically important. In this work, we introduce a comprehensive model that incorporates contributions…

Optics · Physics 2024-04-24 Libang Chen , Jun Yang , Lingye Chen , Yuyang Shui , Yikun Liu , Jianying Zhou

We propose a tomographic method to reconstruct the optical properties of a highly-scattering medium from incoherent acousto-optic measurements. The method is based on the solution to an inverse problem for the diffusion equation and makes…

Optics · Physics 2015-05-14 Guillaume Bal , John C Schotland