English

Multiple scattering limit in optical microscopy

Optics 2017-11-09 v2 Biological Physics

Abstract

Optical microscopy offers a unique insight of biological structures with a sub-micrometer resolution and a minimum invasiveness. However, the inhomogeneities of the specimen itself can induce multiple scattering of light and optical aberrations which limit the observation to depths close to the surface. To predict quantitatively the penetration depth in microscopy, we theoretically derive the single-to-multiple scattering ratio in reflection. From this key quantity, the multiple scattering limit is deduced for various microscopic imaging techniques such as confocal microscopy, optical coherence tomography and related methods.

Keywords

Cite

@article{arxiv.1709.03386,
  title  = {Multiple scattering limit in optical microscopy},
  author = {Amaury Badon and A. Claude Boccara and Geoffroy Lerosey and Mathias Fink and Alexandre Aubry},
  journal= {arXiv preprint arXiv:1709.03386},
  year   = {2017}
}

Comments

18 pages, 7 figures

R2 v1 2026-06-22T21:39:02.717Z