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In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The…

Optics · Physics 2021-01-07 Antoine Boniface , Jonathan Dong , Sylvain Gigan

In an ultrasonic array system, increasing the aperture size to achieve a high resolution requires more transmit and receive channels, thus making it essential to have an analysis technique that can reconstruct the shape and physical…

Optics · Physics 2025-08-21 Kai Yabumoto , Takayoshi Yumii , Kenjiro Kimura

Equivocal 3D lesion segmentation exhibits high inter-observer variability. Conventional deterministic models ignore this aleatoric uncertainty, producing over-confident masks that obscure clinical risks. Conversely, while generative methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Chao Wu , Kangxian Xie , Mingchen Gao

The small correction volume for conventional wavefront shaping methods limits their applications in biological imaging through scattering media. We demonstrate large volume wavefront shaping through a scattering layer with a single…

Biological Physics · Physics 2017-02-20 Xiaodong Tao , Tuwin Lam , Bingzhao Zhu , Qinggele Li , Marc R. Reinig , Joel Kubby

The recent theory of compressive sensing leverages upon the structure of signals to acquire them with much fewer measurements than was previously thought necessary, and certainly well below the traditional Nyquist-Shannon sampling rate.…

Scattering of light in complex media scrambles optical wavefronts and breaks the principles of conventional imaging methods. For decades, researchers have endeavored to conquer the problem by inventing approaches such as adaptive optics,…

We present an imaging technique particularly suited to the detection of a target embedded in a strongly scattering medium. Classical imaging techniques based on the Born approximation fail in this kind of configuration because of multiply…

Classical Physics · Physics 2009-08-21 Alexandre Aubry , Arnaud Derode

Optical focusing through/inside scattering media, like multimode fiber and biological tissues, has significant impact in biomedicine yet considered challenging due to strong scattering nature of light. Previously, promising progress has…

The goal of synthetic aperture imaging is to estimate the reflectivity of a remote region of interest by processing data gathered with a moving sensor which emits periodically a signal and records the backscattered wave. We introduce and…

Image and Video Processing · Electrical Eng. & Systems 2019-07-05 Liliana Borcea , Josselin Garnier

We examine the use of optomechanically-generated squeezing to obtain a sensitivity enhancement for interferometers in the gravitational-wave band. The intrinsic dispersion characteristics of optomechanical squeezing around the mechanical…

Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan

We study the imaging of a penetrable scatterer, aka target, in a waveguide with randomly perturbed boundary. The target is located between a partially coherent source which transmits the wave, and a detector which measures the spatially…

Analysis of PDEs · Mathematics 2018-12-05 Liliana Borcea , Josselin Garnier

As light propagates along a waveguide, a fraction of the field can be reflected by Rayleigh scatterers. In high-quality-factor whispering-gallery-mode microresonators, this intrinsic backscattering is primarily caused by either surface or…

From the earth's crust to the human brain, remitted waves are used for sensing and imaging in a diverse range of diffusive media. Separating the source and detector increases the penetration depth of remitted light, yet rapidly decreases…

Inverse scattering is the process of estimating the spatial distribution of the scattering potential of an object by measuring the scattered wavefields around it. In this paper, we consider reflection tomography of high contrast objects…

Signal Processing · Electrical Eng. & Systems 2020-12-17 Ajinkya Kadu , Hassan Mansour , Petros T. Boufounos

Depth sectioning in reflection microscopy has predominantly relied on temporal coherence gating. Here we show that volumetric reflection tomography at diffraction-limited resolution can be achieved under monochromatic illumination by…

Extending super-resolution imaging techniques to objects hidden in strongly scattering media potentially revolutionize the technical analysis for much broader categories of samples, such as biological tissues. The main challenge is the…

Non-invasive optical focusing inside scattering media is still a big challenge because inhomogeneous media scatter both incoming photons for focusing and outgoing photons for observation. Various approaches, utilizing non-linear…

Optics · Physics 2021-09-17 Dayan Li , Sujit Kumar Sahoo , Huy Quoc Lam , Dong Wang , Cuong Dang

Focusing light into opaque random or scattering media such as biological tissue is a much sought-after goal for biomedical applications such as photodynamic therapy, optical manipulation, and photostimulation. However, focusing with…

Optics · Physics 2014-03-10 Jian Wei Tay , Puxiang Lai , Yuta Suzuki , Lihong V. Wang

Squeezed light is injected into the dark port of gravitational wave interferometers, in order to reduce the quantum noise. A fraction of the interferometer output light can reach the OPO due to sub-optimal isolation of the squeezing…