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Purpose: The scattering phenomenon creates degrading effects in positron emission tomography (PET) and the corresponding events are rejected conventionally. We have proposed a mathematical model to retrace the original line of response of…

Medical Physics · Physics 2022-04-05 Satyajit Ghosh , Pragya Das

In brain oncology, it is routine to evaluate the progress or remission of the disease based on the differences between a pre-treatment and a post-treatment Positron Emission Tomography (PET) scan. Background adjustment is necessary to…

Methodology · Statistics 2019-03-19 Meng Li , Armin Schwartzman

Time of Flight Positron Emission Tomography scanner based on plastic scintillators is being developed at the Jagiellonian University by the J-PET collaboration. The main challenge of the conducted research lies in the elaboration of a…

The Jagiellonian Positron Emission Tomograph (J-PET) is the first PET device built from plastic scintillators. It is a multi-purpose detector designed for medical imaging and for studies of properties of positronium atoms in porous matter…

Modern PET systems reach a spatial resolution of 3-10 mm. A disadvantage of this technique is the diffusion of the positron before its decay with a typical range of ca. 1 mm (depending on its energy). This motion and Compton scattering of…

Instrumentation and Detectors · Physics 2012-02-03 C. Lang , D. Habs , P. G. Thirolf , A. Zoglauer

We develop a positronium imaging method for the Jagiellonian PET (J-PET) scanners based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM). The system matrix elements are calculated on-the-fly for the coincidences…

Instrumentation and Detectors · Physics 2023-10-19 Roman Y. Shopa , Kamil Dulski

PET is a functional imaging technique based on detection of annihilation photons following beta decay producing positrons. In this paper, we present the concept of a new PET system for preclinical applications consisting of a ring of twelve…

Instrumentation and Detectors · Physics 2015-03-19 A. Miceli , P. Amaudruz , F. Benard , D. A. Bryman , L. Kurchaninov , J. P. Martin , A. Muennich , F. Retiere , T. J. Ruth , V. Sossi , A. J. Stoessl

Positronium imaging was recently proposed to image the properties of positronium atoms in the patient body. Positronium properties depend on the size of intramolecular voids and oxygen concentration; therefore, they deliver information…

In this study we address the feasibility and main properties of a positron emission tomograph (PET) based on RPCs. The concept, making use of the converter-plate principle, takes advantage of the intrinsic layered structure of RPCs and its…

Instrumentation and Detectors · Physics 2009-11-07 A. Blanco , V. Chepel , R. Ferreira-Marques , P. Fonte , M. I. Lopes , V. Peskov , A. Policarpo

Here we present new joint reconstruction and regularization techniques inspired by ideas in microlocal analysis and lambda tomography, for the simultaneous reconstruction of the attenuation coefficient and electron density from X-ray…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 James Webber , Eric Todd Quinto , Eric L. Miller

J-PET Framework is an open-source software platform for data analysis, written in C++ and based on the ROOT package. It provides a common environment for implementation of reconstruction, calibration and filtering procedures, as well as for…

Instrumentation and Detectors · Physics 2020-05-28 Wojciech Krzemien , Aleksander Gajos , Krzysztof Kacprzak , Kamil Rakoczy , Grzegorz Korcyl

By profiting from recent developments in detector technologies, making it possible to access a stream of detection events with few-ns time resolutions, a new ptychographic workflow is established. This methodological framework, referred to…

Applied Physics · Physics 2026-03-27 Hoelen L. Lalandec Robert , Arno Annys , Tamazouzt Chennit , Jo Verbeeck

For extending CT field-of-view to perform non-destructive testing, the Symmetric Multi-Linear trajectory Computed Tomography (SMLCT) has been developed as a successful example of non-standard CT scanning modes. However, inevitable geometric…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Zhisheng Wang , Yanxu Sun , Shangyu Li , Legeng Lin , Shunli Wang , Junning Cui

The present paper proposes a novel computational method for parametric imaging of nuclear medicine data. The mathematical procedure is general enough to work for compartmental models of diverse complexity and is effective in the…

Tissues and Organs · Quantitative Biology 2017-05-15 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

Computed Tomography (CT) using synchrotron radiation is a powerful technique that, compared to lab-CT techniques, boosts high spatial and temporal resolution while also providing access to a range of contrast-formation mechanisms. The…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Jiayang Shi , Daniel M. Pelt , K. Joost Batenburg

In positron emission tomography (PET), a clear theoretical model describing how system sensitivity varies as a source is moved trans-axially within the field of view (FOV) is lacking. The current understanding and practical intuition often…

Medical Physics · Physics 2026-01-26 Boheng Lin , Zizhuo Xie , Bo Zhang , Lin Wan , Ao Qiu , Qingguo Xie

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

To accurately quantify in vivo radiotracer uptake using Positron Emission Tomography (PET) is a challenging task due to low signal-to-noise ratio (SNR) and poor spatial resolution of PET camera along with the finite image sampling…

Image and Video Processing · Electrical Eng. & Systems 2020-06-03 Mahbubunnabi Tamal

In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…

Medical Physics · Physics 2025-10-16 Liyang Hu , Chong Chen
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