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Positron Emission Tomography (PET) is a powerful medical imaging technique, but the design and evaluation of new PET scanner technologies present significant challenges. The process is typically divided into three major stages: 1. detector…

Instrumentation and Detectors · Physics 2026-01-30 J. Renner , J. J. Gómez-Cadenas , R. Soleti

Score-based generative models have demonstrated highly promising results for medical image reconstruction tasks in magnetic resonance imaging or computed tomography. However, their application to Positron Emission Tomography (PET) is still…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Imraj RD Singh , Alexander Denker , Riccardo Barbano , Željko Kereta , Bangti Jin , Kris Thielemans , Peter Maass , Simon Arridge

In this paper, we provide a novel method for the estimation of unknown parameters of the Gaussian Mixture Model (GMM) in Positron Emission Tomography (PET). A vast majority of PET imaging methods are based on reconstruction model that is…

Signal Processing · Electrical Eng. & Systems 2023-06-30 Tomislav Matulić , Damir Seršić

Positronium Imaging requires two classes of events: double-coincidences originated from pair of back-to-back annihilation photons and triple-coincidences comprised with two annihilation photons and one additional prompt photon. The standard…

Medical Physics · Physics 2025-08-11 Lech Raczynski , Wojciech Krzemien , Konrad Klimaszewski

In this paper, a methodology is investigated for signal recovery in the presence of non-Gaussian noise. In contrast with regularized minimization approaches often adopted in the literature, in our algorithm the regularization parameter is…

Optimization and Control · Mathematics 2017-01-23 Yosra Marnissi , Yuling Zheng , Emilie Chouzenoux , Jean-Christophe Pesquet

Positron Emission Tomography (PET) is a medical imaging modality that utilizes positron-emitting isotopes, such as Ga-68 and F-18, for many diagnostic purposes. The positron annihilates with an electron from the surrounding area, creating…

In oncology, Positron Emission Tomography imaging is widely used in diagnostics of cancer metastases, in monitoring of progress in course of the cancer treatment, and in planning radiotherapeutic interventions. Accurate and reproducible…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Jakub Czakon , Filip Drapejkowski , Grzegorz Zurek , Piotr Giedziun , Jacek Zebrowski , Witold Dyrka

Scattered coincidences introduce quantitative bias in positron emission tomography (PET) and must be compensated during reconstruction. Conventional scatter estimates typically rely on simplified cylindrical scanner models that omit…

Organ-specific, targeted Field-of-View (FoV) Positron Emission Tomography (PET)/Magnetic Resonance Imaging (MRI) inserts are viable solutions for a number of imaging tasks where whole-body PET/MRI systems lack the necessary sensitivity and…

Instrumentation and Detectors · Physics 2019-09-19 J. M. C. Brown , S. E. Brunner , D. R. Schaart

Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…

Tissues and Organs · Quantitative Biology 2025-11-07 Akhil Ambekar , Robert Zielinski , Ani Eloyan

We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…

We continue studies of the uncertainty quantification problem in emission tomographies such as PET or SPECT when additional multimodal data (e.g., anatomical MRI images) are available. To solve the aforementioned problem we adapt the…

Machine Learning · Statistics 2021-12-03 Fedor Goncharov , Éric Barat , Thomas Dautremer

The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm$^3$, and a high contrast. In this paper we present results of simulations for the full CaLIPSO PET…

We propose in this work a framework for synergistic positron emission tomography (PET)/computed tomography (CT) reconstruction using a joint generative model as a penalty. We use a synergistic penalty function that promotes PET/CT pairs…

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…

We report a study of the original image reconstruction algorithm based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM), developed for the total-body (TB) Jagiellonian PET (J-PET) scanners. The method is…

Parametric imaging is a compartmental approach that processes nuclear imaging data to estimate the spatial distribution of the kinetic parameters governing tracer flow. The present paper proposes a novel and efficient computational method…

Numerical Analysis · Mathematics 2018-08-21 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana

Positron Emission Tomography (PET) is crucial in medicine, but its clinical use is limited due to high signal-to-noise ratio doses increasing radiation exposure. Lowering doses increases Poisson noise, which current denoising methods fail…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Yang Shi , Jingchao Wang , Liangsi Lu , Mingxuan Huang , Ruixin He , Yifeng Xie , Hanqian Liu , Minzhe Guo , Yangyang Liang , Weipeng Zhang , Zimeng Li , Xuhang Chen

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

Reconstruction of the image in Positron Emission Tomographs (PET) requires the knowledge of the system response kernel which describes the contribution of each pixel (voxel) to each tube of response (TOR). This is especially important in…