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The automatic, sensor-based assessment of challenging behavior of persons with dementia is an important task to support the selection of interventions. However, predicting behaviors like apathy and agitation is challenging due to the large…

Machine Learning · Computer Science 2024-08-13 Maximilian Popko , Sebastian Bader , Stefan Lüdtke , Thomas Kirste

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

The utility of Twitter data as a medium to support population-level mental health monitoring is not well understood. In an effort to better understand the predictive power of supervised machine learning classifiers and the influence of…

Information Retrieval · Computer Science 2017-01-31 Danielle Mowery , Craig Bryan , Mike Conway

Early detection of dementia is crucial to devise effective interventions. Comprehensive cognitive tests, while being the most accurate means of diagnosis, are long and tedious, thus limiting their applicability to a large population,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Anusha A. S. , Uma Ranjan , Medha Sharma , Siddharth Dutt

Differential diagnosis of dementia is challenging due to overlapping symptoms, with structural magnetic resonance imaging (MRI) being the primary method for diagnosis. Despite the clinical value of computer-aided differential diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Yitong Li , Tom Nuno Wolf , Sebastian Pölsterl , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Using picture description speech for dementia detection has been studied for 30 years. Despite the long history, previous models focus on identifying the differences in speech patterns between healthy subjects and patients with dementia but…

Computation and Language · Computer Science 2023-08-17 Youxiang Zhu , Nana Lin , Xiaohui Liang , John A. Batsis , Robert M. Roth , Brian MacWhinney

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

Depression is a common mental illness across current human society. Traditional depression assessment relying on inventories and interviews with psychologists frequently suffer from subjective diagnosis results, slow and expensive diagnosis…

Neurons and Cognition · Quantitative Biology 2025-07-01 Siyang Song , Yupeng Huo , Shiqing Tang , Jiaee Cheong , Rui Gao , Michel Valstar , Hatice Gunes

Depression is a mental disorder and can cause a variety of symptoms, including psychological, physical, and social. Speech has been proved an objective marker for the early recognition of depression. For this reason, many studies have been…

Machine Learning · Computer Science 2026-05-12 Loukas Ilias , Dimitris Askounis

Dementia is a neurological syndrome marked by cognitive decline. Alzheimer's disease (AD) and Frontotemporal dementia (FTD) are the common forms of dementia, each with distinct progression patterns. EEG, a non-invasive tool for recording…

Signal Processing · Electrical Eng. & Systems 2024-08-21 Shivani Ranjan , Ayush Tripathi , Harshal Shende , Robin Badal , Amit Kumar , Pramod Yadav , Deepak Joshi , Lalan Kumar

Dialogue systems for mental health care aim to provide appropriate support to individuals experiencing mental distress. While extensive research has been conducted to deliver adequate emotional support, existing studies cannot identify…

Computation and Language · Computer Science 2024-08-13 Seungyeon Seo , Gary Geunbae Lee

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

Sound · Computer Science 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…

Motivation: The importance of clinical data in understanding the pathophysiology of complex disorders has prompted the launch of multiple initiatives designed to generate patient-level data from various modalities. While these studies can…

Speech-based depression detection has shown promise as an objective diagnostic tool, yet the cross-linguistic robustness of acoustic markers and their neurobiological underpinnings remain underexplored. This study extends Cross-Data…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-07 Fuxiang Tao , Dongwei Li , Shuning Tang , Xuri Ge , Wei Ma , Anna Esposito , Alessandro Vinciarelli

Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common neurodegenerative disorders in humans. Because a significant percentage of patients have clinical and pathological features of both diseases, it has been…

Quantitative Methods · Quantitative Biology 2019-06-10 Dhruv Agarwal , Abhishek Srivastava , Edward W Huang

This study investigates whether speech-based depression detection models learn depression-related acoustic biomarkers or instead rely on speaker identity cues. Using the DAIC-WOZ dataset, we propose a data-splitting strategy that controls…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-17 Hsiang-Chen Yeh , Luqi Sun , Aurosweta Mahapatra , Shreeram Suresh Chandra , Emily Mower Provost , Berrak Sisman

Interpreting the environmental, behavioural and psychological data from in-home sensory observations and measurements can provide valuable insights into the health and well-being of individuals. Presents of neuropsychiatric and…

Signal Processing · Electrical Eng. & Systems 2021-05-24 Roonak Rezvani , Samaneh Kouchaki , Ramin Nilforooshan , David J. Sharp , Payam Barnaghi

Depression is a critical concern in global mental health, prompting extensive research into AI-based detection methods. Among various AI technologies, Large Language Models (LLMs) stand out for their versatility in mental healthcare…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-25 Xiangyu Zhang , Hexin Liu , Kaishuai Xu , Qiquan Zhang , Daijiao Liu , Beena Ahmed , Julien Epps

Depression has affected millions of people worldwide and has become one of the most common mental disorders. Early mental disorder detection can reduce costs for public health agencies and prevent other major comorbidities. Additionally,…

Computation and Language · Computer Science 2024-04-09 Giuliano Lorenzoni , Cristina Tavares , Nathalia Nascimento , Paulo Alencar , Donald Cowan
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