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Major depressive disorder persistently stands as a major public health problem. While some progress has been made toward effective treatments, the neural mechanisms that give rise to the disorder remain poorly understood. In this…

Neurons and Cognition · Quantitative Biology 2025-07-23 Matthew Botvinick , Zeb Kurth-Nelson , Timothy Muller , Will Dabney

Dementia, a prevalent neurodegenerative condition, is a major manifestation of Alzheimer's disease (AD). As the condition progresses from mild to severe, it significantly impairs the individual's ability to perform daily tasks…

Machine Learning · Computer Science 2023-11-06 Md Gulzar Hussain , Ye Shiren

Background:Speech patterns have emerged as potential diagnostic markers for conditions with varying etiologies. Machine learning (ML) presents an opportunity to harness these patterns for accurate disease diagnosis. Objective: This review…

Computation and Language · Computer Science 2025-03-10 Birger Moell , Fredrik Sand Aronsson , Per Östberg , Jonas Beskow

Dementia, a neurodegenerative disease, alters speech patterns, creating communication barriers and raising privacy concerns. Current speech technologies, such as automatic speech transcription (ASR), struggle with dementia and atypical…

Computation and Language · Computer Science 2025-07-15 Dominika Woszczyk , Ranya Aloufi , Soteris Demetriou

With more than 300 million people depressed worldwide, depression is a global problem. Due to access barriers such as social stigma, cost, and treatment availability, 60% of mentally-ill adults do not receive any mental health services.…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Albert Haque , Michelle Guo , Adam S Miner , Li Fei-Fei

Depression is a major mental health disorder that is rapidly affecting lives worldwide. Depression not only impacts emotional but also physical and psychological state of the person. Its symptoms include lack of interest in daily…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Shubham Dham , Anirudh Sharma , Abhinav Dhall

Emotions(like fear,anger,sadness,happiness etc.) are the fundamental features of human behavior and governs his/her mental health. The subtlety of emotional fluctuations can be examined through perturbation in conversations or speech.…

Sound · Computer Science 2021-06-04 Susmita Bhaduri , Anirban Bhaduri , Rajib Sarkar

Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…

Speech and language technologies offer valuable opportunities for supporting mental health assessment through objective and interpretable cues. We present a systematic feature-based analysis framework leveraging perceptually grounded…

Artificial Intelligence · Computer Science 2026-05-28 Vassilis Lyberatos , Edmund G. Dervakos , Eleni Adamidi , Athanasios Voulodimos , Giorgos Stamou

As the aging of society continues to accelerate, Alzheimer's Disease (AD) has received more and more attention from not only medical but also other fields, such as computer science, over the past decade. Since speech is considered one of…

Robotics · Computer Science 2022-11-17 Yuanchao Li , Catherine Lai , Divesh Lala , Koji Inoue , Tatsuya Kawahara

Alzheimer's disease (AD) is a neurodegenerative disease that affects nearly 50 million individuals across the globe and is one of the leading causes of deaths globally. It is projected that by 2050, the number of people affected by the…

Machine Learning · Computer Science 2021-10-26 Yash Kumar , Piyush Maheshwari , Shreyansh Joshi , Veeky Baths

Depression is a common mental illness that has to be detected and treated at an early stage to avoid serious consequences. There are many methods and modalities for detecting depression that involves physical examination of the individual.…

Artificial Intelligence · Computer Science 2022-02-08 Kayalvizhi S , Thenmozhi D

Current work on speech-based dementia assessment focuses on either feature extraction to predict assessment scales, or on the automation of existing test procedures. Most research uses public data unquestioningly and rarely performs a…

Audio and Speech Processing · Electrical Eng. & Systems 2025-08-07 Franziska Braun , Christopher Witzl , Andreas Erzigkeit , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

Social media data has been used for detecting users with mental disorders, such as depression. Despite the global significance of cross-cultural representation and its potential impact on model performance, publicly available datasets often…

Computation and Language · Computer Science 2024-10-16 Nuredin Ali , Charles Chuankai Zhang , Ned Mayo , Stevie Chancellor

Depression is underdiagnosed in primary care, yet timely identification remains critical. Recorded clinical encounters, increasingly common with digital scribing technologies, present an opportunity to detect depression from naturalistic…

Computation and Language · Computer Science 2026-04-09 Feng Chen , Manas Bedmutha , Janice Sabin , Andrea Hartzler , Nadir Weibel , Trevor Cohen

Background: Artificial intelligence (AI) models in healthcare depend on the fidelity of diagnostic data, yet the quality of such data is often compromised by variability in clinical documentation practices. In dementia, a condition already…

We describe the development of a model to detect user-level clinical depression based on a user's temporal social media posts. Our model uses a Depression Symptoms Detection (DSD) classifier, which is trained on the largest existing samples…

Computation and Language · Computer Science 2023-03-31 Nawshad Farruque , Randy Goebel , Sudhakar Sivapalan , Osmar R. Zaïane

Speech is usually used for constructing an automatic Alzheimer's dementia (AD) detection system, as the acoustic and linguistic abilities show a decline in people living with AD at the early stages. However, speech includes not only…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-11 Yilin Pan , Yanpei Shi , Yijia Zhang , Mingyu Lu

Over the past decade, machine learning techniques especially predictive modeling and pattern recognition in biomedical sciences from drug delivery system to medical imaging has become one of the important methods which are assisting…

Computer Vision and Pattern Recognition · Computer Science 2016-03-30 Saman Sarraf , Ghassem Tofighi

Depression, a prevalent mental health disorder impacting millions globally, demands reliable assessment systems. Unlike previous studies that focus solely on either detecting depression or predicting its severity, our work identifies…

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