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For measurements designed to accurately determine layer thickness, there is a natural trade-off between sensitivity to optical thickness and lateral resolution due to the angular ray distribution required for a focused beam. We demonstrate…
Measurements of microscale surface patterns are essential for process and quality control in industries across semiconductors, micro-machining, and biomedicines. However, the development of miniaturized and intelligent profiling systems…
Ultrafast electron microscopy aims for imaging transient phenomena occurring on nanoscale. One of its goals is to visualize localized optical and plasmonic modes generated by coherent excitation in the vicinity of various types of…
Mid-infrared reconfigurable edge-enhanced imaging is highly demanded in sensing and vision fields. Here, we propose a novel scheme for mid-infrared upconversion imaging with high tunability between bright-field and edge-enhanced modalities.…
Quantitative phase imaging (QPI) is a label-free technique that provides optical path length information for transparent specimens, finding utility in biology, materials science, and engineering. Here, we present quantitative phase imaging…
THz spectroscopy has reached imaging capability with a spatial resolution of a few micrometres. This property enables measurements and imaging of biological samples like cells. THz photons have very low photon energies in the…
Median filtering is a cornerstone of computational image processing. It provides an effective means of image smoothing, with minimal blurring or softening of edges, invariance to monotonic transformations such as gamma adjustment, and…
Lensless imaging enables exceptionally compact fluorescence sensors, advancing applications in \textit{in vivo} imaging and low-cost, point-of-care diagnostics. These sensors require a filter to block the excitation light while passing…
Diffractive photonic devices manipulate light via local and nonlocal optical modes. Local devices, such as metasurfaces, can shape a wavefront at multiple selected wavelengths, but inevitably modify light across the spectrum; nonlocal…
Optical coherence tomography (OCT) is a label-free, non-invasive 3D imaging tool widely used in both biological research and clinical diagnosis. Current OCT modalities can only visualize specimen tomography without chemical information.…
The sensitivity of thin-film materials and devices to defects motivates extensive research into the optimization of film morphology. This research could be accelerated by automated experiments that characterize the response of film…
Thin film interferometry is a powerful technique for non-invasively measuring liquid film thickness with applications in ophthalmology, but its clinical translation is hindered by the challenges in reconstructing thickness profiles from…
Plenty of quantum information protocols are enabled by manipulation and detection of photonic spectro-temporal degrees of freedom via light-matter interfaces. While present implementations are well suited for high-bandwidth photon sources…
Cell boundary information is crucial for analyzing cell behaviors from time-lapse microscopy videos. Existing supervised cell segmentation tools, such as ImageJ, require tuning various parameters and rely on restrictive assumptions about…
The field of biomedical imaging has undergone a rapid growth in recent years, mostly due to the implementation of ad-hoc designed experimental setups, theoretical support methods and numerical reconstructions. Especially for biological…
Biomedical imaging is unequivocally dependent on the ability to reconstruct interpretable and high-quality images from acquired sensor data. This reconstruction process is pivotal across many applications, spanning from magnetic resonance…
We present a simple nearest-neighbor (NN) approach that synthesizes high-frequency photorealistic images from an "incomplete" signal such as a low-resolution image, a surface normal map, or edges. Current state-of-the-art deep generative…
We introduce HAMscope, a compact, snapshot hyperspectral autofluorescence miniscope that enables real-time, label-free molecular imaging in a wide range of biological systems. By integrating a thin polymer diffuser into a widefield…
Coherent microscopy techniques provide an unparalleled multi-scale view of materials across scientific and technological fields, from structural materials to quantum devices, from integrated circuits to biological cells. Driven by the…
Current biological and medical research is aimed at obtaining a detailed spatiotemporal map of a live cell's interior to describe and predict cell's physiological state. We present here an algorithm for complete 3-D modelling of cellular…