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Cytoplasmic viscoelasticity is crucial for various intracellular processes. However, the dynamic shear modulus, $G(\omega)$, has been reported to vary considerably, often without consistent patterns or rules, even within the same cell.…

Biological Physics · Physics 2025-04-29 H. Ebata , K. Nishizawa , F. A. S. van Esterik , Y. Tao , S. Inokuchi , H. Ise , D. Mizuno

The capabilities of additive manufacturing have facilitated the design and production of mechanical metamaterials with diverse unit cell geometries. Establishing linkages between the vast design space of unit cells and their effective…

Computational Engineering, Finance, and Science · Computer Science 2025-05-05 Hooman Danesh , Maruthi Annamaraju , Tim Brepols , Stefanie Reese , Surya R. Kalidindi

Elasticity is a fundamental cellular property that is related to the anatomy, functionality and pathological state of cells and tissues. However, current techniques based on cell deformation, atomic force microscopy or Brillouin scattering…

We report about a mechanism for surface localization, present in finite defect-free polyatomic lattices described by a tight binding model. Numerical diagonalization and degenerated perturbation theory show that there is a minimum number of…

Mesoscale and Nanoscale Physics · Physics 2019-08-13 Ricardo A. Pinto

Stimuli-responsive macromolecules display large conformational changes during their dynamics, sometimes switching states, and are an integral property for the development of soft functional materials. Here, we introduce a mean-field…

Soft Condensed Matter · Physics 2024-07-02 José López-Molina , Sebastien Groh , Joachim Dzubiella , Arturo Moncho-Jordá

Sorting cells based on their mechanical properties is essential for applications in disease diagnostics, cell therapy, and biomedical research. Deterministic Lateral Displacement (DLD) devices provide a label-free method for achieving such…

Quantitative Methods · Quantitative Biology 2025-12-08 Khayrul Islam , Mehedi Hasan , Yaling Liu

The aim of our work is to study the effect of geometry variation on nucleation times and to address its role in the context of eukaryotic chemotaxis (i.e. the process which allows cells to identify and follow a gradient of chemical…

Statistical Mechanics · Physics 2010-02-10 Carla Bosia , Michele Caselle , Davide Corá

Motivated by elastography that utilizes tissue mechanical properties as biomarkers for liver disease, with the eventual objective of quantitatively linking histopathology and bulk mechanical properties, we develop a micromechanical modeling…

Biological Physics · Physics 2025-01-06 Haritya Shah , Murthy N. Guddati

Understanding the relationship between muscle activation and thickness deformation is critical for diagnosing muscle-related diseases and monitoring muscle health. Although ultrasound technique can measure muscle thickness change during…

Signal Processing · Electrical Eng. & Systems 2024-09-30 Bangyu Lan , Kenan Niu

In this article, we present a contact resistivity extraction method calibrated using a de-embedding structure, called High-Resolution Transmission Line Model (HR-TLM). HR-TLM has the similar infrastructure with Refined TLM (RTLM) or…

Signal Processing · Electrical Eng. & Systems 2025-04-30 Xuanyu Jia , Hongxu Liao , Ming Li

In the last decade, the role of shearing loads has been increasingly suspected to play a determinant impact in the formation of deep pressure ulcers. In vivo observations of such deformations are complex to obtain. Previous studies only…

Medical Physics · Physics 2021-11-16 Alessio Trebbi , Antoine Perrier , Mathieu Bailet , Yohan Payan

Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yan Wang , Xu Wei , Fengze Liu , Jieneng Chen , Yuyin Zhou , Wei Shen , Elliot K. Fishman , Alan L. Yuille

Signals analysis for cytometry remains a challenging task that has a significant impact on uncertainty. Conventional cytometers assume that individual measurements are well characterized by simple properties such as the signal area, width,…

We explore liquid crystal order in a cell with a "dirty" substrate imposing a random surface pinning. Modeling such systems by a random-field xy-model with surface heterogeneity, we find that orientational order in the three-dimensional…

Soft Condensed Matter · Physics 2009-10-13 Leo Radzihovsky , Quan Zhang

The relaxation of a dewetting contact line is investigated theoretically in the so-called "Landau-Levich" geometry in which a vertical solid plate is withdrawn from a bath of partially wetting liquid. The study is performed in the framework…

Fluid Dynamics · Physics 2007-05-25 J. H. Snoeijer , B. Andreotti , G. Delon , M. Fermigier

Polar regions are covered by sea ice, which can be seen as a thin solid elastic sheet with heterogeneous mechanical properties. The dynamics of deformation of a floating solid sheet are primarly governed by gravity, water density, and the…

Fluid Dynamics · Physics 2025-09-03 G. Le Doudic , M. Jafari , J. Barckicke , S. Perrard , A. Eddi

Characterizing the elastic properties of soft materials through bulge testing relies on accurate measurement of deformation, which is experimentally challenging. To avoid measuring deformation, we propose a hydrodynamic bulge test for…

Soft Condensed Matter · Physics 2020-03-17 Vishal Anand , Sanjan C. Muchandimath , Ivan C. Christov

The interaction between turbulence and surface tension is studied numerically using the one-dimensional-turbulence (ODT) model. ODT is a stochastic model simulating turbulent flow evolution along a notional one-dimensional line of sight by…

Fluid Dynamics · Physics 2024-04-16 A. Movaghar , R. Chiodi , M. Oevermann , O. Desjardins , A. R. Kerstein

Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer. It remains challenging for computational approaches to achieve…

Computer Vision and Pattern Recognition · Computer Science 2018-02-07 Jason Causey , Junyu Zhang , Shiqian Ma , Bo Jiang , Jake Qualls , David G. Politte , Fred Prior , Shuzhong Zhang , Xiuzhen Huang

Two-dimensional (2D) mechanical models of confluent tissues have related the mechanical state of a monolayer of cells to the average perimeter length of the cell cross sections, predicting floppiness or rigidity of the material. For the…

Soft Condensed Matter · Physics 2025-01-30 Jairo M. Rojas , Mayisha Z. Nakib , Vivian W. Tang , William M. Brieher , Sascha Hilgenfeldt
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