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Accurate gene regulatory networks can be used to explain the emergence of different phenotypes, disease mechanisms, and other biological functions. Many methods have been proposed to infer networks from gene expression data but have been…

Quantitative Methods · Quantitative Biology 2018-12-11 Phan Nguyen , Rosemary Braun

Edge-exchangeable probabilistic network models generate edges as an i.i.d.~sequence from a discrete measure, providing a simple means for statistical inference of latent network properties. The measure is often constructed using the…

Statistics Theory · Mathematics 2021-09-15 Xinglong Li , Trevor Campbell

Pathophysiolpgical modelling of brain systems from microscale to macroscale remains difficult in group comparisons partly because of the infeasibility of modelling the interactions of thousands of neurons at the scales involved. Here, to…

Neurons and Cognition · Quantitative Biology 2026-01-30 Kang You , Gary Green , Jian Zhang

Granger causality is a widely-used criterion for analyzing interactions in large-scale networks. As most physical interactions are inherently nonlinear, we consider the problem of inferring the existence of pairwise Granger causality…

Machine Learning · Computer Science 2020-01-15 Saurabh Khanna , Vincent Y. F. Tan

In our previous study we have presented an approach to studying lead--lag effect in financial markets using information and network theories. Methodology presented there, as well as previous studies using Pearson's correlation for the same…

Statistical Finance · Quantitative Finance 2014-07-21 Paweł Fiedor

Explaining underlying causes or effects about events is a challenging but valuable task. We define a novel problem of generating explanations of a time series event by (1) searching cause and effect relationships of the time series with…

Computation and Language · Computer Science 2018-04-26 Dongyeop Kang , Varun Gangal , Ang Lu , Zheng Chen , Eduard Hovy

With the advent of high-throughput sequencing (HTS) in molecular biology and medicine, the need for scalable statistical solutions for modeling complex biological systems has become of critical importance. The increasing number of platforms…

Molecular Networks · Quantitative Biology 2022-10-19 Fernando Palluzzi , Mario Grassi

The increasing availability of interventional data offers new opportunities for causal discovery, with gene perturbation studies providing a prominent example. Such data are typically count-valued and subject to substantial measurement…

Methodology · Statistics 2026-03-30 Yijiao Zhang , Hongzhe Li

Sparse covariance matrices play crucial roles by encoding the interdependencies between variables in numerous fields such as genetics and neuroscience. Despite substantial studies on sparse covariance matrices, existing methods face several…

Methodology · Statistics 2026-03-03 Rakheon Kim , Irina Gaynanova

Unraveling the causal relationships among the execution of process activities is a crucial element in predicting the consequences of process interventions and making informed decisions regarding process improvements. Process discovery…

Artificial Intelligence · Computer Science 2025-01-15 Fabiana Fournier , Lior Limonad , Inna Skarbovsky , Yuval David

Causal inference is a fundamental research topic for discovering the cause-effect relationships in many disciplines. However, not all algorithms are equally well-suited for a given dataset. For instance, some approaches may only be able to…

Machine Learning · Computer Science 2024-03-11 Zhipeng Ma , Marco Kemmerling , Daniel Buschmann , Chrismarie Enslin , Daniel Lütticke , Robert H. Schmitt

A communication network can be modeled as a directed connected graph with edge weights that characterize performance metrics such as loss and delay. Network tomography aims to infer these edge weights from their pathwise versions measured…

Optimization and Control · Mathematics 2019-08-12 Mahmood Ettehad , Nick Duffield , Gregory Berkolaiko

We establish a new framework for statistical estimation of directed acyclic graphs (DAGs) when data are generated from a linear, possibly non-Gaussian structural equation model. Our framework consists of two parts: (1) inferring the…

Machine Learning · Statistics 2013-11-15 Po-Ling Loh , Peter Bühlmann

Entropic causal inference is a recent framework for learning the causal graph between two variables from observational data by finding the information-theoretically simplest structural explanation of the data, i.e., the model with smallest…

Machine Learning · Computer Science 2025-09-23 Spencer Compton , Kristjan Greenewald , Dmitriy Katz , Murat Kocaoglu

Emergency Medical Services (EMS) demand load has become a considerable burden for many government authorities, and EMS demand is often an early indicator for stress in communities, a warning sign of emerging problems. In this paper, we…

Machine Learning · Computer Science 2020-04-28 Kasun Bandara , Christoph Bergmeir , Sam Campbell , Deborah Scott , Dan Lubman

Networks are frequently used to model complex systems comprised of interacting elements. While edges capture the topology of direct interactions, the true complexity of many systems originates from higher-order patterns in paths by which…

Social and Information Networks · Computer Science 2022-10-04 Christoph Gote , Vincenzo Perri , Ingo Scholtes

Granger causality has been employed to investigate causality relations between components of stationary multiple time series. We generalize this concept by developing statistical inference for local Granger causality for multivariate…

Methodology · Statistics 2025-08-12 Yan Liu , Masanobu Taniguchi , Hernando Ombao

Identifying causal relations among simultaneously acquired signals is an important problem in multivariate time series analysis. For linear stochastic systems Granger proposed a simple procedure called the Granger causality to detect such…

Chaotic Dynamics · Physics 2009-11-10 Yonghong Chen , Govindan Rangarajan , Jianfeng Feng , Mingzhou Ding

Estimating causal effects under networked interference from observational data is a crucial yet challenging problem. Most existing methods mainly rely on the networked unconfoundedness assumption, which guarantees the identification of…

Machine Learning · Computer Science 2026-01-28 Weilin Chen , Ruichu Cai , Jie Qiao , Yuguang Yan , José Miguel Hernández-Lobato

Exploratory analysis of time series data can yield a better understanding of complex dynamical systems. Granger causality is a practical framework for analysing interactions in sequential data, applied in a wide range of domains. In this…

Machine Learning · Computer Science 2021-01-20 Ričards Marcinkevičs , Julia E. Vogt