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In the field of medical image analysis, image registration is a crucial technique. Despite the numerous registration models that have been proposed, existing methods still fall short in terms of accuracy and interpretability. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Jiaofen Nan , Gaodeng Fan , Kaifan Zhang , Chen Zhao , Fubao Zhu , Weihua Zhou

An important task in image processing and neuroimaging is to extract quantitative information from the acquired images in order to make observations about the presence of disease or markers of development in populations. Having a…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , Andrew J. Plassard , Larry T. Davis , Allen T. Newton , Susan M Resnick , Bennett A. Landman

Diffeomorphic image registration (DIR) is a fundamental task in 3D medical image analysis that seeks topology-preserving deformations between image pairs. To ensure diffeomorphism, a common approach is to model the deformation field as the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Mohammadjavad Matinkia , Nilanjan Ray

The glioblastoma multiforme is the most common malignant primary brain tumor and is one of the highest malignant human neoplasms. During the course of disease, the evaluation of tumor volume is an essential part of the clinical follow-up.…

Computer Vision and Pattern Recognition · Computer Science 2011-03-10 Jan Egger , Miriam H. A. Bauer , Daniela Kuhnt , Barbara Carl , Christoph Kappus , Bernd Freisleben , Christopher Nimsky

We propose in this paper a texture-invariant 2D keypoints descriptor specifically designed for matching preoperative Magnetic Resonance (MR) images with intraoperative Ultrasound (US) images. We introduce a matching-by-synthesis strategy,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Hassan Rasheed , Reuben Dorent , Maximilian Fehrentz , Tina Kapur , William M. Wells , Alexandra Golby , Sarah Frisken , Julia A. Schnabel , Nazim Haouchine

Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry Imaging (MSI) is a powerful technique for spatially resolved molecular profiling and cancer biomarker discovery. Recent advances, including a novel multiomics workflow, enable…

Methodology · Statistics 2025-09-03 Francesco Denti , Cecilia Balocchi , Vanna Denti , Giulia Capitoli

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

Recent developments in spatial omics technologies have enabled the generation of high dimensional molecular data, such as transcriptomes, proteomes, and epigenomes, within their spatial tissue context, either through coprofiling on the same…

Quantitative Methods · Quantitative Biology 2026-01-21 Esra Busra Isik , Yusuf Hakan Usta , Haozhe Liu , Maryam Riazi , William Roach , Hongpeng Zhou , Magnus Rattray , Sokratia Georgaka

We analyze a variational time discretization of geodesic calculus on finite- and certain classes of infinite-dimensional Riemannian manifolds. We investigate the fundamental properties of discrete geodesics, the associated discrete…

Numerical Analysis · Mathematics 2013-03-25 Martin Rumpf , Benedikt Wirth

Computational modeling of Multiresolution- Fractional Brownian motion (fBm) has been effective in stochastic multiscale fractal texture feature extraction and machine learning of abnormal brain tissue segmentation. Further, deep…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 A. Temtam , L. Pei , K. Iftekharuddin

We present a scalable method for brain cell identification in multiview confocal light sheet microscopy images. Our algorithmic pipeline includes a hierarchical registration approach and a novel multiview version of semantic deconvolution…

Computer Vision and Pattern Recognition · Computer Science 2015-11-05 Marco Paciscopi , Ludovico Silvestri , Francesco Saverio Pavone , Paolo Frasconi

This paper proposes LLaFS, the first attempt to leverage large language models (LLMs) in few-shot segmentation. In contrast to the conventional few-shot segmentation methods that only rely on the limited and biased information from the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Lanyun Zhu , Tianrun Chen , Deyi Ji , Jieping Ye , Jun Liu

Neuroimaging is the growing area of neuroscience devoted to produce data with the goal of capturing processes and dynamics of the human brain. We consider the problem of inferring the brain connectivity network from time dependent…

Methodology · Statistics 2021-05-28 Saverio Ranciati , Alberto Roverato , Alessandra Luati

Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studies. However, most existing studies focus on individual gene…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Junzhuo Liu , Xuemei Du , Daniel Reisenbuchler , Ye Chen , Markus Eckstein , Christian Matek , Friedrich Feuerhake , Dorit Merhof

Recently, the theory of diffusion maps was extended to a large class of local kernels with exponential decay which were shown to represent various Riemannian geometries on a data set sampled from a manifold embedded in Euclidean space.…

Classical Analysis and ODEs · Mathematics 2015-09-28 Tyrus Berry , John Harlim

Living biological tissue is a complex system, constantly growing and changing in response to external and internal stimuli. These processes lead to remarkable and intricate changes in shape. Modeling and understanding both natural and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Edwin Tay , Nazli Tümer , Amir A. Zadpoor

The structure of grey matter has long been a key focus in neuroscience, as cell morphology varies by type and can be affected by neurological conditions. Understanding these variations is essential for studying brain function and disease.…

Biological Physics · Physics 2025-08-27 Charlie Aird-Rossiter , Hui Zhang , Daniel C. Alexander , Derek K. Jones , Marco Palombo

Accurate brain tumor diagnosis relies on the assessment of multiple Magnetic Resonance Imaging (MRI) sequences. However, in clinical practice, the acquisition of certain sequences may be affected by factors like motion artifacts or contrast…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Moinak Bhattacharya , Saumya Gupta , Annie Singh , Chao Chen , Gagandeep Singh , Prateek Prasanna

The geometry of weight spaces and functional manifolds of neural networks play an important role towards 'understanding' the intricacies of ML. In this paper, we attempt to solve certain open questions in ML, by viewing them through the…

Machine Learning · Computer Science 2020-12-18 Guruprasad Raghavan , Matt Thomson

Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…

Computational Engineering, Finance, and Science · Computer Science 2016-09-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits