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Neither of the two prevalent theories, namely thermodynamic stability and kinetic stability, provides a comprehensive understanding of protein folding. The thermodynamic theory is misleading because it assumes that free energy is the…

Biological Physics · Physics 2013-07-22 Ji Xu , Mengzhi Han , Ying Ren , Jinghai Li

When a fluid-immersed array of lamellae or filaments that is attached to a substrate is dried, evaporation leads to the formation of menisci on the tips of the plates or pillars that bring them together. Similarly, when hair dries it clumps…

Soft Condensed Matter · Physics 2015-06-22 Zhiyan Wei , Tobias Schneider , Jungchul Kim , Ho-Young Kim , Joanna Aizenberg , L. Mahadevan

Self-organization of active matter as well as driven granular matter in non-equilibrium dynamical states has attracted considerable attention not only from the fundamental and application viewpoints but also as a model to understand the…

Soft Condensed Matter · Physics 2015-09-14 Yuta Komatsu , Hajime Tanaka

We study the dynamics of the solid to liquid transition for a model material made of elastic particles immersed in a viscous fluid. The interaction between particle surfaces includes their viscous lubrication, a sharp repulsion when they…

Fluid Dynamics · Physics 2015-05-14 P. Rognon , I. Einav , C. Gay

Turbulence in the flow of fluid through a pipe can be suppressed by buoyancy forces. As the suppression of turbulence leads to severe heat transfer deterioration, this is an important and undesirable phenomenon in both heating and cooling…

Fluid Dynamics · Physics 2021-07-01 Elena Marensi , Shuisheng He , Ashley P. Willis

The mechanisms of cold- and pressure-denaturation of proteins are matter of debate and are commonly understood as due to water-mediated interactions. Here we study several cases of proteins, with or without a unique native state, with or…

Biological Physics · Physics 2026-01-13 Valentino Bianco , Giancarlo Franzese

We report that protein confinement within nanoscopic vesicular compartments corresponds to a liquid-liquid phase transition with the protein/water within vesicle lumen interacting very differently than in bulk. We show this effect leads to…

Water activity and its relationship with interactions stabilising lamellar stacks of mixed lipid bilayers in their fluid state are investigated by means of osmotic pressure measurements coupled with small-angle x-ray scattering. The…

We construct a Hamiltonian for a single domain protein where the contact enthalpy and the chain entropy decrease linearly with the number of native contacts. The hydration effect upon protein unfolding is included by modeling water as ideal…

Condensed Matter · Physics 2009-11-07 Audun Bakk , Johan S. Hoye , Alex Hansen

Protein-stabilised emulsions can be seen as mixtures of unadsorbed proteins and of protein-stabilised droplets. To identify the contributions of these two components to the overall viscosity of sodium caseinate o/w emulsions, the…

Soft Condensed Matter · Physics 2019-01-30 Marion Roullet , Paul S. Clegg , William J. Frith

Three-dimensional, time-dependent direct simulations of step emulsification micro-devices highlight two essential mechanisms for droplet formation: first, the onset of an adverse pressure gradient driving a back-flow of the continuous phase…

Computational Physics · Physics 2020-06-22 Andrea Montessori , Marco Lauricella , Sauro Succi , Elad Stolovicki , David A. Weitz

Helices are a key folding motif in protein structure. The question which factors determine helix stability for a given polypeptide or protein is an ongoing challenge. Here we use van der Waals corrected density-functional theory to address…

Chemical Physics · Physics 2015-03-13 Mariana Rossi , Volker Blum , Matthias Scheffler

This paper presents a new finite element (FE) formulation for liquid shells that is based on an explicit, 3D surface discretization using $C^1$-continuous finite elements constructed from NURBS interpolation. Both displacement-based and…

Computational Engineering, Finance, and Science · Computer Science 2017-01-04 Roger A. Sauer , Thang X. Duong , Kranthi K. Mandadapu , David J. Steigmann

Urea denatures proteins due to its strong tendency to dehydrate the first solvation shell via urea-residue preferential binding. However, even after extensive experimental and computational investigations, the influence of urea on the…

Soft Condensed Matter · Physics 2022-12-05 Luis A. Baptista , Yani Zhao , Kurt Kremer , Debashish Mukherji , Robinson Cortes-Huerto

The phase behavior of membrane proteins stems from a complex synergy with the amphiphilic molecules required for their solubilization. We show that ionization of a pH-sensitive surfactant, LDAO, bound to a bacterial photosynthetic protein,…

Soft Condensed Matter · Physics 2009-11-07 R. Piazza , M. Pierno , E. Vignati , G. Venturoli , F. Francia , A. Mallardi , G. Palazzo

Liquid liquid phase separation (LLPS) mediated by pi-cation bonds between tyrosine and arginine residues are of biological importance. To understand the interactions between proteins in the condensed phase in close analogy to complex…

Biological Physics · Physics 2020-08-19 Aditya N. Singh , Arun Yethiraj

Membrane deformation inside living cells is crucial for the proper shaping of various intracellular organelles and is necessary during the fission/fusion processes that allow membrane recycling and transport (e.g. endocytosis). Proteins…

Biological Physics · Physics 2016-01-20 Urška Jelerčič , Nir S. Gov

Comments: 6 pages RevTeX, 6 Postscript figures. We review a statistical mechanics treatment of the stability of globular proteins based on a simple model Hamiltonian taking into account protein self interactions and protein-water…

Condensed Matter · Physics 2009-10-31 Alex Hansen , Mogens H. Jensen , Kim Sneppen , Giovanni Zocchi

The combustion of liquid fuels emulsified with water have long generated interest in the internal combustion engine research community. Typically, these fuels consist of small quantities of water emulsified with ultrasonification or other…

Applied Physics · Physics 2020-01-28 Gurjap Singh , Elio Lopes , Nicholas Hentges , Albert Ratner

Elastoviscoplastic (EVP) fluid flows are driven by a non-trivial interplay between the elastic, viscous, and plastic properties, which under certain conditions can transition the otherwise laminar flow into complex flow instabilities with…

Soft Condensed Matter · Physics 2025-08-14 Christopher S. From , Vedad Dzanic , Vahid Niasar , Emilie Sauret