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Physics-informed neural networks (PINNs) are extensively used to represent various physical systems across multiple scientific domains. The same can be said for cardiac electrophysiology, wherein fully-connected neural networks (FCNNs) have…
Cardiovascular disease (CVD) remains a leading cause of death, and primary prevention through personalized interventions is crucial. This paper introduces MyDigiTwin, a framework that integrates health digital twins with personal health…
In medical science, it is very important to gather multiple data on different diseases and one of the most important objectives of the data is to investigate the diseases. Myocardial infarction is a serious risk factor in mortality and in…
Cardiac digital twins (CDTs) provide personalized in-silico cardiac representations and hold great potential for precision medicine in cardiology. However, whole-heart CDT models that simulate the full organ-scale electromechanics of all…
Personalised 3D vascular models are valuable for diagnosis, prognosis and treatment planning in patients with cardiovascular disease. Traditionally, such models have been constructed with explicit representations such as meshes and voxel…
Objective: In this review, we aim to provide an analysis of current cardiac ablation techniques, such as radiofrequency ablation (RF), cryoablation, and pulsed-field ablation (PFA), with a focus on the role of computational modeling in…
Early recognition of abnormal rhythms in ECG signals is crucial for monitoring and diagnosing patients' cardiac conditions, increasing the success rate of the treatment. Classifying abnormal rhythms into exact categories is very challenging…
Electrocardiogram (ECG) signals play critical roles in the clinical screening and diagnosis of many types of cardiovascular diseases. Despite deep neural networks that have been greatly facilitated computer-aided diagnosis (CAD) in many…
Electrocardiogram (ECG) is one of the non-invasive and low-risk methods to monitor the condition of the human heart. Any abnormal pattern(s) in the ECG signal is an indicative measure of malfunctioning of the heart, termed as arrhythmia.…
The electrocardiogram or ECG has been in use for over 100 years and remains the most widely performed diagnostic test to characterize cardiac structure and electrical activity. We hypothesized that parallel advances in computing power,…
The combination of data and models, enhanced by AI methodologies, leads to the paradigm called Digital Twins. This concept is expected to bring unprecedented support to personalized medicine. The combination of mathematical and numerical…
For plane-wave and many-spiral states of the experimentally based Luo-Rudy 1 model of heart tissue in large (8 cm square) domains, we show that an explicit space-time-adaptive time-integration algorithm can achieve an order of magnitude…
Micro-Electro-Mechanical-Systems are complex structures, often involving nonlinearites of geometric and multiphysics nature, that are used as sensors and actuators in countless applications. Starting from full-order representations, we…
Deep learning has the potential to automate echocardiogram analysis for early detection of heart disease. Based on a qualitative analysis of design concerns, this study suggests that predicting normal heart function instead of disease…
Cardiac digital twins hold great promise for personalized medicine, but they currently depend on complex constitutive models of tissue mechanics that are often over-parameterized for the clinical context. To address this, we introduce…
Electrocardiogram (ECG) is widely used in healthcare applications, such as arrhythmia detection and sleep monitoring, making accurate ECG analysis critically essential. Traditional deep learning models for ECG are task-specific, with…
With the rapid digitalization of healthcare systems, there has been a substantial increase in the generation and sharing of private health data. Safeguarding patient information is essential for maintaining consumer trust and ensuring…
Background: Artificial intelligence techniques have shown great potential in cardiology, especially in quantifying cardiac biventricular function, volume, mass, and ejection fraction (EF). However, its use in clinical practice is not…
Computational models of cardiac structure and function are increasingly central to the development of subject-specific cardiac digital twins, enabling improved characterization of contractile dysfunction, pathological remodeling, and…
Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…