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The primary goal of this paper is to develop a method that quantifies how activity in one brain region can explain future activity in another region. Here, we propose the mixed effects spectral vector-autoregressive (ME-SpecVar) model to…

Applications · Statistics 2022-10-07 Anastasiia Malinovskaia

Alterations in functional brain connectivity characterize neurodegenerative disorders such as Alzheimer's disease (AD) and frontotemporal dementia (FTD). As a non-invasive and cost-effective technique, electroencephalography (EEG) is…

Applications · Statistics 2025-11-19 Paolo Victor Redondo , Raphaël Huser , Hernando Ombao

Functional brain imaging through electroencephalography (EEG) relies upon the analysis and interpretation of high-dimensional, spatially organized time series. We propose to represent time-localized frequency domain characterizations of EEG…

In multi-condition EEG experiments, brain activity is recorded as subjects perform various tasks or are exposed to different stimuli. The recorded signals are commonly transformed into time-frequency representations, which often display…

Methodology · Statistics 2025-07-29 Xiaomeng Ju , Thaddeus Tarpey , Hyung G Park

Our goal is to model and measure functional and effective (directional) connectivity in multichannel brain physiological signals (e.g., electroencephalograms, local field potentials). The difficulties from analyzing these data mainly come…

Applications · Statistics 2017-12-04 Lechuan Hu , Norbert Fortin , Hernando Ombao

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

Methodology · Statistics 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Multivariate functional data can be intrinsically multivariate like movement trajectories in 2D or complementary like precipitation, temperature, and wind speeds over time at a given weather station. We propose a multivariate functional…

Methodology · Statistics 2021-10-06 Alexander Volkmann , Almond Stöcker , Fabian Scheipl , Sonja Greven

We consider the problem of extracting features from passive, multi-channel electroencephalogram (EEG) devices for downstream inference tasks related to high-level mental states such as stress and cognitive load. Our proposed method…

Signal Processing · Electrical Eng. & Systems 2022-03-02 Guodong Chen , Hayden S. Helm , Kate Lytvynets , Weiwei Yang , Carey E. Priebe

This paper develops a novel statistical approach to characterize temporally localised cross-oscillatory interactions between channels in a functional brain network. Brain signals are generally nonstationary and the proposed framework uses…

Methodology · Statistics 2026-02-10 Haibo Wu , Marina I. Knight , Hernando Ombao

This paper introduces an innovative approach to Attention-deficit/hyperactivity disorder (ADHD) diagnosis by employing deep learning (DL) techniques on electroencephalography (EEG) signals. This method addresses the limitations of current…

Computers and Society · Computer Science 2024-12-04 Medha Pappula , Syed Muhammad Anwar

This paper presents a general framework for modeling dependence in multivariate time series. Its fundamental approach relies on decomposing each signal in a system into various frequency components and then studying the dependence…

Methodology · Statistics 2021-04-01 Hernando Ombao , Marco Pinto

Depression and Attention Deficit Hyperactivity Disorder (ADHD) stand out as the common mental health challenges today. In affective computing, speech signals serve as effective biomarkers for mental disorder assessment. Current research,…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-05 Shuanglin Li , Siyang Song , Rajesh Nair , Syed Mohsen Naqvi

The neuromagnetic activity (magnetoencephalogram, MEG) from healthy human brain and from an epileptic patient against chromatic flickering stimuli has been earlier analyzed on the basis of a memory functions formalism (MFF). Information…

Medical Physics · Physics 2010-06-29 O. Yu. Panischev , S. A. Demin , J. Bhattacharya

We study multimodal affect modeling when EEG and peripheral physiology are asynchronous, which most fusion methods ignore or handle with costly warping. We propose Cross-Temporal Attention Fusion (CTAF), a self-supervised module that learns…

Machine Learning · Computer Science 2026-02-04 Arian Khorasani , Théophile Demazure

Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

Applications · Statistics 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani

Electroencephalography signals (EEGs) contain rich multi-scale information crucial for understanding brain states, with potential applications in diagnosing and advancing the drug development landscape. However, extracting meaningful…

Machine Learning · Computer Science 2025-09-26 D. Darankoum , C. Habermacher , J. Volle , S. Grudinin

Mixed membership models are a flexible class of probabilistic data representations used for unsupervised and semi-supervised learning, allowing each observation to partially belong to multiple clusters or features. In this manuscript, we…

A common concern in the field of functional data analysis is the challenge of temporal misalignment, which is typically addressed using curve registration methods. Currently, most of these methods assume the data is governed by a single…

Depression is a major cause of global mental illness and significantly influences suicide rates. Timely and accurate diagnosis is essential for effective intervention. Electroencephalography (EEG) provides a non-invasive and accessible…

Signal Processing · Electrical Eng. & Systems 2025-11-11 Soujanya Hazra , Sanjay Ghosh

Functional magnetic resonance imaging or functional MRI (fMRI) is a very popular tool used for differing brain regions by measuring brain activity. It is affected by physiological noise, such as head and brain movement in the scanner from…

Methodology · Statistics 2023-10-30 Fangyijie Wang , Michael Salter-Townshend
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