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Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

We propose a novel computational framework for analyzing electroencephalography (EEG) time series using methods from stringology, the study of efficient algorithms for string processing, to systematically identify and characterize recurrent…

Neurons and Cognition · Quantitative Biology 2026-03-05 Anat Dahan , Samah Ghazawi

This study investigates the detection and classification of depressive and non-depressive states using deep learning approaches. Depression is a prevalent mental health disorder that substantially affects quality of life, and early…

Quantitative Methods · Quantitative Biology 2026-01-19 Mohammad Reza Yousefi , Hajar Ismail Al-Tamimi , Amin Dehghani

Timely characterizations of risks in economic and financial systems play an essential role in both economic policy and private sector decisions. However, the informational content of low-frequency variables and the results from conditional…

Econometrics · Economics 2022-09-07 Matteo Iacopini , Aubrey Poon , Luca Rossini , Dan Zhu

Brain activation and connectivity analyses in task-based functional magnetic resonance imaging (fMRI) experiments with multiple subjects are currently at the forefront of data-driven neuroscience. In such experiments, interest often lies in…

Applications · Statistics 2019-04-02 Daniel Spencer , Rajarshi Guhaniyogi , Raquel Prado

Statistical analysis of high-dimensional functional times series arises in various applications. Under this scenario, in addition to the intrinsic infinite-dimensionality of functional data, the number of functional variables can grow with…

Statistics Theory · Mathematics 2022-01-14 Qin Fang , Shaojun Guo , Xinghao Qiao

Historically, the analysis of stimulus-dependent time-frequency patterns has been the cornerstone of most electroencephalography (EEG) studies. The abnormal oscillations in high-frequency waves associated with psychotic disorders during…

Neurons and Cognition · Quantitative Biology 2023-01-05 Sadi Md. Redwan , Md Palash Uddin , Anwaar Ulhaq , Muhammad Imran Sharif

Normative modeling is an emerging and promising approach to effectively study disorder heterogeneity in individual participants. In this study, we propose a novel normative modeling method by combining conditional variational autoencoder…

Machine Learning · Computer Science 2022-11-17 Xuetong Wang , Kanhao Zhao , Rong Zhou , Alex Leow , Ricardo Osorio , Yu Zhang , Lifang He

We present a Bayesian approach for modeling multivariate, dependent functional data. To account for the three dominant structural features in the data--functional, time dependent, and multivariate components--we extend hierarchical dynamic…

Methodology · Statistics 2019-07-02 Daniel R. Kowal , David S. Matteson , David Ruppert

Cross-center data heterogeneity and annotation unreliability significantly challenge the intelligent diagnosis of diseases using brain signals. A notable example is the EEG-based diagnosis of neurodegenerative diseases, which features…

Signal Processing · Electrical Eng. & Systems 2026-02-09 Zhenxi Song , Ruihan Qin , Huixia Ren , Zhen Liang , Yi Guo , Min Zhang , Zhiguo Zhang

Attention Deficit Hyperactivity Disorder (ADHD) is a common brain disorder in children that can persist into adulthood, affecting social, academic, and career life. Early diagnosis is crucial for managing these impacts on patients and the…

Machine Learning · Computer Science 2025-09-11 Ali Amini , Mohammad Alijanpour , Behnam Latifi , Ali Motie Nasrabadi

Mixed spatial autoregressive (SAR) models with numerical covariates have been well studied. However, as non-numerical data, such as functional data and compositional data, receive substantial amounts of attention and are applied to…

Applications · Statistics 2018-11-08 Huiwen Wang , Tingting Huang , Shanshan Wang

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that is challenging to diagnose and requires advanced approaches for reliable and transparent identification and classification. It is characterized by a…

Machine Learning · Computer Science 2026-02-04 Abdul Rehman , Ilona Heldal , Jerry Chun-Wei Lin

High-dimensional inference based on matrix-valued data has drawn increasing attention in modern statistical research, yet not much progress has been made in large-scale multiple testing specifically designed for analysing such data sets.…

Methodology · Statistics 2021-06-18 Xu Han , Sanat Sarkar , Shiyu Zhang

In multivariate longitudinal studies, associations between outcomes often exhibit time-varying and individual level heterogeneity, motivating the modeling of correlations as an explicit function of time and covariates. However, most…

To understand multifactorial conditions such as Alzheimers disease (AD) we need brain signatures that predict the impact of multiple pathologies and their interactions. To help uncover the relationships between brain circuits and cognitive…

Quantitative Methods · Quantitative Biology 2018-12-31 Alexandra Badea , Natalie A Delpratt , RJ Anderson , Russell Dibb , Yi Qi , Hongjiang Wei , Chunlei Liu , William C Wetsel , Brian B Avants , Carol Colton

Electroencephalograph (EEG) timeseries signals are characterized by significant noise and coarse spatial resolution, which complicates the classification of neurodegenerative diseases. Even SOTA deep learning architectures struggle to…

Machine Learning · Computer Science 2026-05-26 Tawsik Jawad , Gowtham Atluri , Vikram Ravindra

In this paper, we consider a bidimensional autoregressive model of order 1 with $\alpha-$stable noise. Since in this case the classical measure of dependence known as the covariance function is not defined, the spatio-temporal dependence…

Probability · Mathematics 2019-11-27 Aleksandra Grzesiek , Agnieszka Wyłomańska

Expecting events in time leads to more efficient behavior. A remarkable early finding in the study of temporal expectancy is the foreperiod effect on reaction times; i.e., the influence or reaction time of the time period between a warning…

Quantitative Methods · Quantitative Biology 2016-11-02 Joaquin Rapela , Marissa Westerfield , Jeanne Townsend , Scott Makeig

Electroencephalogram-based brain-computer interface (BCI) has potential applications in various fields, but their development is hindered by limited data and significant cross-individual variability. Inspired by the principles of learning…

Neural and Evolutionary Computing · Computer Science 2024-09-30 Junyan Li , Bin Hu , Zhi-Hong Guan
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