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A system can be driven between metastable configurations by a time-dependent driving protocol, which uses external control parameters to change the potential energy of the system. Here we investigate the correspondence between driving…

Statistical Mechanics · Physics 2022-12-27 Miranda D. Louwerse , David A. Sivak

We analyst in detail a new approach to the monitoring and forecasting of the onset of transitions in high dimensional complex systems (see Phys. Rev. Lett . vol. 113, 264102 (2014)) by application to the Tangled Nature Model of evolutionary…

Adaptation and Self-Organizing Systems · Physics 2015-08-03 Duccio Piovani , Jelena Grujic , Henrik Jeldtoft Jensen

Ecosystems often undergo abrupt regime shifts in response to gradual external changes. These shifts are theoretically understood as a regime switch between alternative stable states of the ecosystem dynamical response to smooth changes in…

Populations and Evolution · Quantitative Biology 2015-02-18 Jose A. Capitan , Jose A. Cuesta

We develop a variational neural-network framework to determine the most probable path (MPP) of a 3D active Brownian particle (ABP) by directly minimizing the Onsager-Machlup integral (OMI). To obtain the OMI, we use the Onsager-Machlup…

Stochastic vegetation-water dynamical systems play a pivotal role in ecological stability, biodiversity, water resource management, and adaptation to climate change. This research proposes a machine learning-based method for analyzing rare…

Dynamical Systems · Mathematics 2024-02-29 Yang Li , Shenglan Yuan , Shengyuan Xu

We consider the problem of sampling transition paths between two given metastable states of a molecular system, e.g. a folded and unfolded protein or products and reactants of a chemical reaction. Due to the existence of high energy…

Biomolecules · Quantitative Biology 2023-07-19 Lars Holdijk , Yuanqi Du , Ferry Hooft , Priyank Jaini , Bernd Ensing , Max Welling

Optimal control theory deals with finding protocols to steer a system between assigned initial and final states, such that a trajectory-dependent cost function is minimized. The application of optimal control to stochastic systems is an…

Statistical Mechanics · Physics 2024-09-18 Julia Sanders , Marco Baldovin , Paolo Muratore-Ginanneschi

Multistability is a phenomenon prevalent in many natural systems. In climate, for example, it allows the possibility of irreversible consequences on planetary scale as a result of climate change. Indeed, a climate ``tipping element'' is a…

Atmospheric and Oceanic Physics · Physics 2026-04-14 George Datseris , Johannes Lohmann , Oisín Hamilton , Jacob Haqq-Misra

We propose a systematic methodology to identify the topological phase transition through a self-supervised machine learning model, which is trained to correlate system parameters to the non-local observables in time-of-flight experiments of…

Quantum Gases · Physics 2021-09-01 Chi-Ting Ho , Daw-Wei Wang

Here we use a very simple conceptual model in an attempt to reduce essential parts of the complex nonlinearity of abrupt glacial climate changes (the so-called Dansgaard-Oeschger events) to a few simple principles, namely (i) a threshold…

Geophysics · Physics 2020-01-29 H. Braun , A. Ganopolski , M. Christl , D. R. Chialvo

With rising global temperatures Earth's tipping elements are becoming increasingly more vulnerable to crossing their critical thresholds. The reaching of such tipping points does not only impact other tipping elements through their…

Adaptation and Self-Organizing Systems · Physics 2025-05-08 Tom Bdolach , Jürgen Kurths , Serhiy Yanchuk

Tipping points associated with bifurcations (B-tipping) or induced by noise (N-tipping) are recognized mechanisms that may potentially lead to sudden climate change. We focus here a novel class of tipping points, where a sufficiently rapid…

Dynamical Systems · Mathematics 2013-02-14 Peter Ashwin , Sebastian Wieczorek , Renato Vitolo , Peter Cox

Tipping points are one of the hot topics in modern physics of complex systems. But what is a tipping point? A generic definition declares it as ``a state of the system where a small change in its parameters can lead to a significant change…

Populations and Evolution · Quantitative Biology 2026-02-25 Alan Hastings , Sergei Petrovskii , Valerio Lucarini , Andrew Morozov

In this study, we investigate the transition path of a free active Brownian particle (ABP) on a two-dimensional plane between two given states. The extremum conditions for the most probable path connecting the two states are derived using…

Statistical Mechanics · Physics 2024-05-20 Kento Yasuda , Kenta Ishimoto

For sampling multiple pathways in a rugged energy landscape, we propose a novel action-based path sampling method using the Onsager-Machlup action functional. Inspired by the Fourier-path integral simulation of a quantum mechanical system,…

Biological Physics · Physics 2015-05-18 Hiroshi Fujisaki , Motoyuki Shiga , Akinori Kidera

Adaptive multilevel splitting algorithms have been introduced rather recently for estimating tail distributions in a fast and efficient way. In particular, they can be used for computing the so-called reactive trajectories corresponding to…

Numerical Analysis · Mathematics 2014-12-25 Joran Rolland , Eric Simonnet

A number of biological systems can be modeled by Markov chains. Recently, there has been an increasing concern about when biological systems modeled by Markov chains will perform a dynamic phenomenon called overshoot. In this article, we…

Quantitative Methods · Quantitative Biology 2014-08-27 Chen Jia , Minping Qian , Daquan Jiang

Bistable autonomous systems can be found inmany areas of science. When the intrinsic noise intensity is large, these systems exhibits stochastic transitions from onemetastable steady state to another. In electronic bistable memories, these…

Statistical Mechanics · Physics 2024-05-14 Léopold Van Brandt , Jean-Charles Delvenne

We present a computer-assisted approach to locating approximate coarse optimal switching policies between stationary states of chemically reacting systems described by microscopic/stochastic evolution rules. The ``coarse time-stepper"…

Optimization and Control · Mathematics 2007-05-23 Antonios Armaou , Ioannis G. Kevrekidis

In biology phenotypic switching is a common bet-hedging strategy in the face of uncertain environmental conditions. Existing mathematical models often focus on periodically changing environments to determine the optimal phenotypic response.…

Populations and Evolution · Quantitative Biology 2018-03-14 Peter G. Hufton , Yen Ting Lin , Tobias Galla
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