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Image reconstruction from insufficient data is common in computed tomography (CT), e.g., image reconstruction from truncated data, limited-angle data and sparse-view data. Deep learning has achieved impressive results in this field.…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Yixing Huang , Alexander Preuhs , Michael Manhart , Guenter Lauritsch , Andreas Maier

This work aims efficiently estimating the posterior distribution of kinetic parameters for dynamic positron emission tomography (PET) imaging given a measurement of time of activity curve. Considering the inherent information loss from…

Medical Physics · Physics 2023-10-25 Xiaofeng Liu , Thibault Marin , Tiss Amal , Jonghye Woo , Georges El Fakhri , Jinsong Ouyang

Automated segmentation of cancerous lesions in PET/CT images is a vital initial task for quantitative analysis. However, it is often challenging to train deep learning-based segmentation methods to high degree of accuracy due to the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Shadab Ahamed , Arman Rahmim

This study presents FP-PET, a comprehensive approach to medical image segmentation with a focus on CT and PET images. Utilizing a dataset from the AutoPet2023 Challenge, the research employs a variety of machine learning models, including…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Yixin Chen , Ourui Fu , Wenrui Shao , Zhaoheng Xie

The distribution of absorbed dose in radionuclide therapy with Lu$^{177}$ can be approximated by convolving an image of the time-integrated activity distribution with a dose voxel kernel representing different tissue types. This fast but…

Machine Learning · Statistics 2026-03-25 Luciano Melodia

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Purpose: This paper describes a new method to apply deep-learning algorithms for automatic segmentation of radiosensitive organs from 3D tomographic CT images before computing organ doses using a GPU-based Monte Carlo code. Methods: A deep…

Medical Physics · Physics 2020-09-09 Zhao Peng , Xi Fang , Pingkun Yan , Hongming Shan , Tianyu Liu , Xi Pei , Ge Wang , Bob Liu , Mannudeep K. Kalra , X. George Xu

Positron emission tomography (PET) reconstruction has become an ill-posed inverse problem due to low-count projection data, and a robust algorithm is urgently required to improve imaging quality. Recently, the deep image prior (DIP) has…

Image and Video Processing · Electrical Eng. & Systems 2021-11-01 Chenyu Shen , Wenjun Xia , Hongwei Ye , Mingzheng Hou , Hu Chen , Yan Liu , Jiliu Zhou , Yi Zhang

Objective: Image reconstruction in high resolution PET scanners with depth of interaction (DOI) capability is computationally challenging due to the high sampling in detector and image space. This study evaluates the use of a virtual…

Digital Volume Correlation (DVC) is widely used for the analysis of three-dimensional displacement and strain fields based on CT scans. However, the applicability of DVC methods is limited when it comes to geomaterials: CT speckles are…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Chengsheng Li , Zhijun Liu

Synchrotron-based X-ray computed tomography is widely used for investigating inner structures of specimens at high spatial resolutions. However, potential beam damage to samples often limits the X-ray exposure during tomography experiments.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Ziling Wu , Tekin Bicer , Zhengchun Liu , Vincent De Andrade , Yunhui Zhu , Ian T. Foster

Image segmentation is pivotal in medical image analysis, facilitating clinical diagnosis, treatment planning, and disease evaluation. Deep learning has significantly advanced automatic segmentation methodologies by providing superior…

Image and Video Processing · Electrical Eng. & Systems 2026-01-22 Zhengyong Huang , Ning Jiang , Xingwen Sun , Lihua Zhang , Peng Chen , Jens Domke , Yao Sui

The MR-Linac can enable real-time radiotherapy adaptation. However, real-time image acquisition is restricted to 2D to obtain sufficient spatial resolution, hindering accurate 3D segmentation. By reducing spatial resolution fast 3D imaging…

Medical Physics · Physics 2023-10-18 Samuel Fransson , David Tilly , Robin Strand

To accurately quantify in vivo radiotracer uptake using Positron Emission Tomography (PET) is a challenging task due to low signal-to-noise ratio (SNR) and poor spatial resolution of PET camera along with the finite image sampling…

Image and Video Processing · Electrical Eng. & Systems 2020-06-03 Mahbubunnabi Tamal

Background: Pleural Effusions (PE) is a common finding in many different clinical conditions, but accurately measuring their volume from CT scans is challenging. Purpose: To improve PE segmentation and quantification for enhanced clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-10-07 Sanhita Basu , Tomas Fröding , Ali Teymur Kahraman , Dimitris Toumpanakis , Tobias Sjöblom

We present a method that lowers the dose required for a ptychographic reconstruction by adaptively scanning the specimen, thereby providing the required spatial information redundancy in the regions of highest importance. The proposed…

Computational Physics · Physics 2022-03-30 Marcel Schloz , Johannes Müller , Thomas C. Pekin , Wouter Van den Broek , Christoph T. Koch

In this study, 18F-FDG PET/CT brain scans of 50 patients with head and neck malignant lesions were employed to systematically assess the relationship between the amount of injected dose (10%, 8%, 6%, 5%, 4%, 3%, 2%, and 1% of standard dose)…

Medical Physics · Physics 2021-03-22 Behnoush Sanaei , Reza Faghihi , Hossein Arabi

Quantification of local metabolic tumor volume (MTV) chan-ges after Chemo-radiotherapy would allow accurate tumor response evaluation. Currently, local MTV changes in esophageal (soft-tissue) cancer are measured by registering follow-up PET…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Sadegh Riyahi , Wookjin Choi , Chia-Ju Liu , Saad Nadeem , Shan Tan , Hualiang Zhong , Wengen Chen , Abraham J. Wu , James G. Mechalakos , Joseph O. Deasy , Wei Lu

Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Faisal Mahmood , Richard Chen , Sandra Sudarsky , Daphne Yu , Nicholas J. Durr

Positron emission tomography (PET) scans expose patients to radiation, which can be mitigated by reducing the dose, albeit at the cost of diminished quality. This makes low-dose (LD) PET recovery an active research area. Previous studies…

Image and Video Processing · Electrical Eng. & Systems 2026-03-11 Ghulam Nabi Ahmad Hassan Yar , Himashi Peiris , Victoria Mar , Cameron Dennis Pain , Zhaolin Chen