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In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Ehab Abdelmaguid , Jolene Huang , Sanjay Kenchareddy , Disha Singla , Laura Wilke , Mai H. Nguyen , Ilkay Altintas

Accuracy and precision of measurements are important for patient follow up in oncology but, unfortunately, partial volume effects introduce an undesired variability between observers. Super resolution techniques (SR) combine multiple…

Medical Physics · Physics 2015-06-25 Estanislao Oubel , Hubert Beaumont , Antoine Iannessi

Dose painting of hypoxic tumour sub-volumes using positron-emission tomography (PET) has been shown to improve tumour control in silico in several sites. Pancreatic cancer presents a more stringent challenge, given its proximity to critical…

Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fumio Hashimoto , Kuang Gong

To evaluate how partial volume correction (PVC) affects the reproducibility of 18F-FDG PET radiomic features in lymphoma lesions, with respect to lesion volume and tissue type. This single-center retrospective study included 131 newly…

Positron Emission Tomography (PET) imaging is a vital tool in medical diagnostics, offering detailed insights into molecular processes within the human body. However, PET images often suffer from complicated noise, which can obscure…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Xuehua Ye , Hongxu Yang , Adam J. Schwarz

Artificial intelligence (AI) is entering medical imaging, mainly enhancing image reconstruction. Nevertheless, improvements throughout the entire processing, from signal detection to computation, potentially offer significant benefits. This…

Machine Learning · Computer Science 2023-10-27 Stephan Naunheim , Yannick Kuhl , David Schug , Volkmar Schulz , Florian Mueller

Long lasting efforts have been made to reduce radiation dose and thus the potential radiation risk to the patient for computed tomography acquisitions without severe deterioration of image quality. To this end, numerous reconstruction and…

Medical Physics · Physics 2024-10-07 Elias Eulig , Björn Ommer , Marc Kachelrieß

Most radiotracers used in dynamic positron emission tomography (PET) scanning act in a linear time-invariant fashion so that the measured time-course data are a convolution between the time course of the tracer in the arterial supply and…

Low-count positron emission tomography (PET) reconstruction is a challenging inverse problem due to severe degradations arising from Poisson noise, photon scarcity, and attenuation correction errors. Existing deep learning methods typically…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zheng Zhang , Hao Tang , Yingying Hu , Zhanli Hu , Jing Qin

X-ray photon-counting detectors (PCDs) are drawing an increasing attention in recent years due to their low noise and energy discrimination capabilities. The energy/spectral dimension associated with PCDs potentially brings great benefits…

Medical Physics · Physics 2020-07-08 Mengzhou Li , David S. Rundle , Ge Wang

Low Dose CT Denoising research aims to reduce the risks of radiation exposure to patients. Recently researchers have used deep learning to denoise low dose CT images with promising results. However, approaches that use mean-squared-error…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Sepehr Ataei , Javad Alirezaie , Paul Babyn

Anatomically guided PET reconstruction using MRI information has been shown to have the potential to improve PET image quality. However, these improvements are limited to PET scans with paired MRI information. In this work we employed a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Weijie Gan , Huidong Xie , Carl von Gall , Günther Platsch , Michael T. Jurkiewicz , Andrea Andrade , Udunna C. Anazodo , Ulugbek S. Kamilov , Hongyu An , Jorge Cabello

Positron emission tomography (PET) is widely used for clinical diagnosis. As PET suffers from low resolution and high noise, numerous efforts try to incorporate anatomical priors into PET image reconstruction, especially with the…

Medical Physics · Physics 2019-12-17 Nuobei Xie , Kuang Gong , Ning Guo , Zhixin Qin , Zhifang Wu , Huafeng Liu , Quanzheng Li

Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Dac Thai Nguyen , Trung Thanh Nguyen , Huu Tien Nguyen , Thanh Trung Nguyen , Huy Hieu Pham , Thanh Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen

Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Tzu-An Song , Samadrita Roy Chowdhury , Fan Yang , Joyita Dutta

Positron emission tomography (PET) is the most sensitive molecular imaging modality routinely applied in our modern healthcare. High radioactivity caused by the injected tracer dose is a major concern in PET imaging and limits its clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Yuxin Xue , Yige Peng , Lei Bi , Dagan Feng , Jinman Kim

Contrast-enhanced computed tomography (CECT) is pivotal for highlighting tissue perfusion and vascularity, yet its clinical ubiquity is impeded by the invasive nature of contrast agents and radiation risks. While virtual contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Zilong Li , Dongyang Li , Chenglong Ma , Zhan Feng , Dakai Jin , Junping Zhang , Hao Luo , Fan Wang , Hongming Shan

As a sensitive functional imaging technique, positron emission tomography (PET) plays a critical role in early disease diagnosis. However, obtaining a high-quality PET image requires injecting a sufficient dose (standard dose) of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Caiwen Jiang , Mianxin Liu , Kaicong Sun , Dinggang Shen

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

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