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Positron emission tomography(PET) image reconstruction is an ill-posed inverse problem and suffers from high level of noise due to limited counts received. Recently deep neural networks especially convolutional neural networks(CNN) have…
Solving computer vision problems through machine learning, one often encounters lack of sufficient training data. To mitigate this we propose the use of ensembles of weak learners based on spectral total-variation (STV) features (Gilboa…
To acquire high-quality positron emission tomography (PET) images while reducing the radiation tracer dose, numerous efforts have been devoted to reconstructing standard-dose PET (SPET) images from low-dose PET (LPET). However, the success…
Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…
Purpose: Historically, spot scanning proton therapy (SSPT) treatment planning utilizes dose volume constraints and linear-energy-transfer (LET) volume constraints separately to balance tumor control and organs-at-risk (OARs) protection. We…
Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…
Synthetic PET images are valuable for quantitative imaging workflow development, scalable virtual imaging trials, and deep learning model training, but conventional physics-based simulation approaches are computationally intensive, limited…
Low-dose computed tomography (CT) has attracted a major attention in the medical imaging field, since CT-associated x-ray radiation carries health risks for patients. The reduction of CT radiation dose, however, compromises the…
The use of deep learning has successfully solved several problems in the field of medical imaging. Deep learning has been applied to the CT denoising problem successfully. However, the use of deep learning requires large amounts of data to…
Recent work has shown that Variational Autoencoders (VAEs) can be used to upper-bound the information rate-distortion (R-D) function of images, i.e., the fundamental limit of lossy image compression. In this paper, we report an improved…
Positron Emission Mammography imaging system (PEMi) is a nuclear medicine diagnosis method dedicated for breast imaging. It provides a better resolution in detection of millimeter-sized breast tumors than whole-body PET. To address the…
Traditional X-ray computed tomography (CT) scanning strategies typically select projection angles uniformly and allocate dose equally. In practice, however, CT scans often need to be fast, radiation-efficient, and adaptive. Sparse-view…
Tracking the pose of instruments is a central problem in image-guided surgery. For microscopic scenarios, optical coherence tomography (OCT) is increasingly used as an imaging modality. OCT is suitable for accurate pose estimation due to…
Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…
To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…
Traditional beamforming of medical ultrasound images relies on sampling rates significantly higher than the actual Nyquist rate of the received signals. This results in large amounts of data to store and process, imposing hardware and…
Conventional pulse-echo ultrasound suffers when low-cost probes deliver only narrow fractional bandwidths, elongating pulses and erasing high-frequency detail. We address this limitation by learning a data-driven mapping from band-limited…
This paper reviewed the machine learning-based studies for quantitative positron emission tomography (PET). Specifically, we summarized the recent developments of machine learning-based methods in PET attenuation correction and low-count…
The "pre-training then fine-tuning (FT)" paradigm is widely adopted to boost the model performance of deep learning-based methods for medical volumetric segmentation. However, conventional full FT incurs high computational and memory costs.…
Patient motion during PET is inevitable. Its long acquisition time not only increases the motion and the associated artifacts but also the patient's discomfort, thus PET acceleration is desirable. However, accelerating PET acquisition will…