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We developed pgMAP, an analysis pipeline to map gRNA sequencing reads from dual-targeting CRISPR screens. pgMAP output includes a dual gRNA read counts table and quality control metrics including the proportion of correctly-paired reads and…

Genomics · Quantitative Biology 2023-06-02 Phoebe C. R. Parrish , Daniel J. Groso , James D. Thomas , Robert K. Bradley , Alice H. Berger

This document contains the mathematical introduction to RORPack - a Python software library for robust output tracking and disturbance rejection for linear PDE systems. The RORPack library is open-source and freely available at…

Optimization and Control · Mathematics 2019-02-27 Lassi Paunonen

We argue that the Julia programming language is a compelling alternative to implementations in Python and C++ for common data analysis workflows in high energy physics. We compare the speed of implementations of different workflows in Julia…

Computational Physics · Physics 2021-04-13 Marcel Stanitzki , Jan Strube

Gaussian processes (GPs) are a widely used regression tool, but the cubic complexity of exact solvers limits their scalability. To address this challenge, we extend the GPRat library by incorporating a fully GPU-resident GP prediction…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-24 Henrik Möllmann , Dirk Pflüger , Alexander Strack

This article is a sequel to "GPU implementation of a ray-surface intersection algorithm in CUDA" (arXiv:2209.02878) [1]. Its main focus is PyCUDA which represents a Python scripting approach to GPU run-time code generation in the Compute…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-05 Raymond Leung

This paper introduces pycvxset, a new Python package to manipulate and visualize convex sets. We support polytopes and ellipsoids, and provide user-friendly methods to perform a variety of set operations. For polytopes, pycvxset supports…

Systems and Control · Electrical Eng. & Systems 2024-10-16 Abraham P. Vinod

In software development there is a constant pressure to produce code faster and faster without compromising on quality. New tools supporting developers are created in response to this demand. Currently a new generation of such solutions is…

Software Engineering · Computer Science 2023-01-13 Mateusz Jaworski , Dariusz Piotrkowski

Git is used as the distributed version control system for many open-source software projects. One Git-based service, GitHub, is the most common code hosting and repository service for open-source software projects. For researchers that…

Software Engineering · Computer Science 2021-01-22 Abdulkadir Şeker , Banu Diri , Halil Arslan , Mehmet Fatih Amasyalı

There are plenty of excellent plotting libraries. Each excels at a different use case: one is good for printed 2D publication figures, the other at interactive 3D graphics, a third has excellent L A TEX integration or is good for creating…

AlphaTwirl is a Python library that summarizes large event data into multivariate categorical data, which can be regarded as generalizations of histograms. The output can be imported as data frames in R and pandas. With their rich set of…

Computational Physics · Physics 2019-09-20 Tai Sakuma

High-level synthesis (HLS) tools have brought FPGA development into the mainstream, by allowing programmers to design architectures using familiar languages such as C, C++, and OpenCL. While the move to these languages has brought…

Hardware Architecture · Computer Science 2019-10-11 Johannes de Fine Licht , Torsten Hoefler

GEANT4 is a particle physics simulation tool used to develop and optimize radiation detectors. While C++ based examples exist, Python's growing popularity necessitates the development of a more accessible Python bindings interface. This…

High Energy Physics - Experiment · Physics 2024-12-10 Patrick Stowell , Robert Foster , Almahdi Elhamri

The evaluation of new computing languages for a large community, like HEP, involves comparison of many aspects of the languages' behaviour, ecosystem and interactions with other languages. In this paper we compare a number of languages…

High Energy Physics - Experiment · Physics 2024-05-09 Graeme Andrew Stewart , Philippe Gras , Benedikt Hegner , Atell Krasnopolski

Mining and storage of data from software repositories is typically done on a per-project basis, where each project uses a unique combination of data schema, extraction tools, and (intermediate) storage infrastructure. We introduce…

Software Engineering · Computer Science 2020-08-17 Alex Serban , Magiel Bruntink , Joost Visser

With the rapid growth of open-source ecosystems (e.g., Linux) and domain-specific software projects (e.g., aerospace), efficient management of reusable artifacts is becoming increasingly crucial for software reuse. The multi-level feature…

Software Engineering · Computer Science 2025-07-08 Dongming Jin , Zhi Jin , Nianyu Li , Kai Yang , Linyu Li , Suijing Guan

Library migration is a common but error-prone task in software development. Developers may need to replace one library with another due to reasons like changing requirements or licensing changes. Migration typically entails updating and…

Software Engineering · Computer Science 2026-02-03 Daniel Ramos , Catarina Gamboa , Inês Lynce , Vasco Manquinho , Ruben Martins , Claire Le Goues

In this chapter, we describe the Parallel Sparse Computation Toolkit (PSCToolkit), a suite of libraries for solving large-scale linear algebra problems in an HPC environment. In particular, we focus on the tools provided for the solution of…

Numerical Analysis · Mathematics 2025-01-09 Pasqua D'Ambra , Fabio Durastante , Salvatore Filippone

Reverse engineering tools remain monolithic and imperative compared to the advancement of modern compiler architectures: analyses are tied to a single mutable representation, making them difficult to extend or refine, and forcing premature…

Programming Languages · Computer Science 2026-03-31 Chang Liu , Yihao Sun , Thomas Gilray , Kristopher Micinski

Learning computer programming has been always challenging. Since the sixties of the last century, many researchers developed Visual Programming Languages (VPLs) to help in this regard. In this thesis, ten VPLs were specifically selected,…

Software Engineering · Computer Science 2020-11-11 Mahmoud Samir Fayed

With the advances in machine learning, there is a growing interest in AI-enabled tools for autocompleting source code. GitHub Copilot, also referred to as the "AI Pair Programmer", has been trained on billions of lines of open source GitHub…

Software Engineering · Computer Science 2023-04-28 Beiqi Zhang , Peng Liang , Xiyu Zhou , Aakash Ahmad , Muhammad Waseem