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Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

Recently, Transformers have shown promising performance in various vision tasks. To reduce the quadratic computation complexity caused by the global self-attention, various methods constrain the range of attention within a local region to…

Computer Vision and Pattern Recognition · Computer Science 2021-12-30 Sitong Wu , Tianyi Wu , Haoru Tan , Guodong Guo

Capturing global contextual information plays a critical role in breast ultrasound (BUS) image classification. Although convolutional neural networks (CNNs) have demonstrated reliable performance in tumor classification, they have inherent…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Bryar Shareef , Min Xian , Aleksandar Vakanski , Haotian Wang

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Automated classification of histopathological whole-slide images (WSI) of breast tissue requires analysis at very high resolutions with a large contextual area. In this paper, we present context-aware stacked convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2017-05-11 Babak Ehteshami Bejnordi , Guido Zuidhof , Maschenka Balkenhol , Meyke Hermsen , Peter Bult , Bram van Ginneken , Nico Karssemeijer , Geert Litjens , Jeroen van der Laak

In digital histopathology, entire neoplasm segmentation on Whole Slide Image (WSI) of Hepatocellular Carcinoma (HCC) plays an important role, especially as a preprocessing filter to automatically exclude healthy tissue, in histological…

Image and Video Processing · Electrical Eng. & Systems 2023-07-13 Zhuxian Guo , Qitong Wang , Henning Müller , Themis Palpanas , Nicolas Loménie , Camille Kurtz

Despite remarkable efforts been made, the classification of gigapixels whole-slide image (WSI) is severely restrained from either the constrained computing resources for the whole slides, or limited utilizing of the knowledge from different…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Ming Feng , Kele Xu , Nanhui Wu , Weiquan Huang , Yan Bai , Changjian Wang , Huaimin Wang

Whole slide images (WSIs) are the gold standard for pathological diagnosis and sub-typing. Current main-stream two-step frameworks employ offline feature encoders trained without domain-specific knowledge. Among them, attention-based…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Mingrui Ma , Chentao Li , Pan Huang , Jing Qin

Accurate segmentation of organs or lesions from medical images is crucial for reliable diagnosis of diseases and organ morphometry. In recent years, convolutional encoder-decoder solutions have achieved substantial progress in the field of…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Bingzhi Chen , Yishu Liu , Zheng Zhang , Guangming Lu , Adams Wai Kin Kong

Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations. Often, this approach directly applies "natural image…

Existing image inpainting methods leverage convolution-based downsampling approaches to reduce spatial dimensions. This may result in information loss from corrupted images where the available information is inherently sparse, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Shuang Chen , Amir Atapour-Abarghouei , Hubert P. H. Shum

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

In some medical imaging tasks and other settings where only small parts of the image are informative for the classification task, traditional CNNs can sometimes struggle to generalise. Manually annotated Regions of Interest (ROI) are…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Alessandro Fontanella , Antreas Antoniou , Wenwen Li , Joanna Wardlaw , Grant Mair , Emanuele Trucco , Amos Storkey

The recently developed vision transformer (ViT) has achieved promising results on image classification compared to convolutional neural networks. Inspired by this, in this paper, we study how to learn multi-scale feature representations in…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Chun-Fu Chen , Quanfu Fan , Rameswar Panda

Transformers have recently shown promise for medical image applications, leading to an increasing interest in developing such models for medical image registration. Recent advancements in designing registration Transformers have focused on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Junyu Chen , Yihao Liu , Yufan He , Yong Du

This paper tackles the high computational/space complexity associated with Multi-Head Self-Attention (MHSA) in vanilla vision transformers. To this end, we propose Hierarchical MHSA (H-MHSA), a novel approach that computes self-attention in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Yun Liu , Yu-Huan Wu , Guolei Sun , Le Zhang , Ajad Chhatkuli , Luc Van Gool

Accurate and timely cancer diagnosis from histopathological slides is vital for effective clinical decision-making. This paper introduces DepViT-CAD, a deployable AI system for multi-class cancer diagnosis in histopathology. At its core is…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Ashkan Shakarami , Lorenzo Nicole , Rocco Cappellesso , Angelo Paolo Dei Tos , Stefano Ghidoni

Manually annotating nuclei from the gigapixel Hematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 João D. Nunes , Diana Montezuma , Domingos Oliveira , Tania Pereira , Jaime S. Cardoso

Histopathology image analysis plays a crucial role in cancer diagnosis. However, training a clinically applicable segmentation algorithm requires pathologists to engage in labour-intensive labelling. In contrast, weakly supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Gang Xu , Shuhao Wang , Lingyu Zhao , Xiao Chen , Tongwei Wang , Lang Wang , Zhenwei Luo , Dahan Wang , Zewen Zhang , Aijun Liu , Wei Ba , Zhigang Song , Huaiyin Shi , Dingrong Zhong , Jianpeng Ma

Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-15 Ravi Kant Gupta , Shounak Das , Amit Sethi