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Automatic medical image segmentation has wide applications for disease diagnosing. However, it is much more challenging than natural optical image segmentation due to the high-resolution of medical images and the corresponding huge…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Ziqiang Li , Rentuo Tao , Qianrun Wu , Bin Li

Graph-based methods have been extensively applied to whole-slide histopathology image (WSI) analysis due to the advantage of modeling the spatial relationships among different entities. However, most of the existing methods focus on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Tsai Hor Chan , Fernando Julio Cendra , Lan Ma , Guosheng Yin , Lequan Yu

We present Token-UNet, adopting the TokenLearner and TokenFuser modules to encase Transformers into UNets. While Transformers have enabled global interactions among input elements in medical imaging, current computational challenges hinder…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Louis Fabrice Tshimanga , Andrea Zanola , Federico Del Pup , Manfredo Atzori

This paper introduces MAD-MIL, a Multi-head Attention-based Deep Multiple Instance Learning model, designed for weakly supervised Whole Slide Images (WSIs) classification in digital pathology. Inspired by the multi-head attention mechanism…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Hassan Keshvarikhojasteh , Josien Pluim , Mitko Veta

3D Swin Transformer (3D-ST) known for its hierarchical attention and window-based processing, excels in capturing intricate spatial relationships within images. Spatial-spectral Transformer (SST), meanwhile, specializes in modeling…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Muhammad Ahmad , Manuel Mazzara , Salvatore Distifano

We present a novel attention mechanism: Causal Attention (CATT), to remove the ever-elusive confounding effect in existing attention-based vision-language models. This effect causes harmful bias that misleads the attention module to focus…

Computer Vision and Pattern Recognition · Computer Science 2021-03-08 Xu Yang , Hanwang Zhang , Guojun Qi , Jianfei Cai

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

In this study, we proposed a deep Swin-Vision Transformer-based transfer learning architecture for robust multi-cancer histopathological image classification. The proposed framework integrates a hierarchical Swin Transformer with…

Image and Video Processing · Electrical Eng. & Systems 2026-04-13 Muazzem Hussain Khan , Tasdid Hasnain , Md. Jamil khan , Ruhul Amin , Md. Shamim Reza , Md. Al Mehedi Hasan , Md Ashad Alam

In recent years, the integration of pre-trained foundational models with multiple instance learning (MIL) has improved diagnostic accuracy in computational pathology. However, existing MIL methods focus on optimizing feature extractors and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 Le Feng , Li Xiao

Transformer-based methods have demonstrated impressive results in medical image restoration, attributed to the multi-head self-attention (MSA) mechanism in the spatial dimension. However, the majority of existing Transformers conduct…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Zhiwen Yang , Haowei Chen , Ziniu Qian , Yang Zhou , Hui Zhang , Dan Zhao , Bingzheng Wei , Yan Xu

Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Yi Zheng , Rushin H. Gindra , Emily J. Green , Eric J. Burks , Margrit Betke , Jennifer E. Beane , Vijaya B. Kolachalama

Classical multiple instance learning (MIL) methods are often based on the identical and independent distributed assumption between instances, hence neglecting the potentially rich contextual information beyond individual entities. On the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Daniel Reisenbüchler , Sophia J. Wagner , Melanie Boxberg , Tingying Peng

Transformers have shown great success in medical image segmentation. However, transformers may exhibit a limited generalization ability due to the underlying single-scale self-attention (SA) mechanism. In this paper, we address this issue…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Md Mostafijur Rahman , Radu Marculescu

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transferable feature representations via self-supervised learning…

Whole-slide images (WSIs) from cancer patients contain rich information that can be used for medical diagnosis or to follow treatment progress. To automate their analysis, numerous deep learning methods based on convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Lucas Sancéré , Noémie Moreau , Katarzyna Bozek

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

This paper delves into the challenges and advancements in the field of medical image segmentation, particularly focusing on breast cancer diagnosis. The authors propose a novel Transformer-based segmentation model that addresses the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Weijie He , Runyuan Bao , Yiru Cang , Jianjun Wei , Yang Zhang , Jiacheng Hu

Multiple Instance Learning (MIL) has become the predominant approach for classification tasks on gigapixel histopathology whole slide images (WSIs). Within the MIL framework, single WSIs (bags) are decomposed into patches (instances), with…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Daniel Sens , Ario Sadafi , Francesco Paolo Casale , Nassir Navab , Carsten Marr

Transformer has been applied in the field of computer vision due to its excellent performance in natural language processing, surpassing traditional convolutional neural networks and achieving new state-of-the-art. ViT divides an image into…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Yuang Liu , Zhiheng Qiu , Xiaokai Qin
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