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Diversification is a useful tool for exploring large collections of information items. It has been used to reduce redundancy and cover multiple perspectives in information-search settings. Diversification finds applications in many…

Data Structures and Algorithms · Computer Science 2026-02-05 Honglian Wang , Sijing Tu , Aristides Gionis

The widespread availability of large amounts of genomic data on the SARS-CoV-2 virus, as a result of the COVID-19 pandemic, has created an opportunity for researchers to analyze the disease at a level of detail unlike any virus before it.…

Machine Learning · Computer Science 2021-10-20 Zahra Tayebi , Sarwan Ali , Murray Patterson

Memory-augmented neural networks (MANNs) provide better inference performance in many tasks with the help of an external memory. The recently developed differentiable neural computer (DNC) is a MANN that has been shown to outperform in…

Hardware Architecture · Computer Science 2022-02-16 Yaoyu Tao , Zhengya Zhang

DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important.…

Machine Learning · Computer Science 2023-11-07 Marcel Khalifa , Barak Hoffer , Orian Leitersdorf , Robert Hanhan , Ben Perach , Leonid Yavits , Shahar Kvatinsky

Domain adaptation algorithms are useful when the distributions of the training and the test data are different. In this paper, we focus on the problem of instrumental variation and time-varying drift in the field of sensors and measurement,…

Computer Vision and Pattern Recognition · Computer Science 2017-06-23 Ke Yan , Lu Kou , David Zhang

Anomaly detection is challenging, especially for large datasets in high dimensions. Here we explore a general anomaly detection framework based on dimensionality reduction and unsupervised clustering. We release DRAMA, a general python…

Machine Learning · Computer Science 2020-06-25 Alireza Vafaei Sadr , Bruce A. Bassett , Martin Kunz

In data-scarce scenarios, deep learning models often overfit to noise and irrelevant patterns, which limits their ability to generalize to unseen samples. To address these challenges in medical image segmentation, we introduce Diff-UMamba,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Dhruv Jain , Romain Modzelewski , Romain Herault , Clement Chatelain , Eva Torfeh , Sebastien Thureau

Multivariate signal processing is often based on dimensionality reduction techniques. We propose a new method, Dynamical Component Analysis (DyCA), leading to a classification of the underlying dynamics and - for a certain type of dynamics…

Signal Processing · Electrical Eng. & Systems 2019-03-19 Bastian Seifert , Katharina Korn , Steffen Hartmann , Christian Uhl

Personalized medicine remains a major challenge for scientists. The rapid growth of Machine learning and Deep learning has made them a feasible al- ternative for predicting the most appropriate therapy for individual patients. However, the…

Machine Learning · Computer Science 2025-06-10 Antonio Jesús Banegas-Luna , Horacio Pérez-Sánchez

Data series motif discovery represents one of the most useful primitives for data series mining, with applications to many domains, such as robotics, entomology, seismology, medicine, and climatology, and others. The state-of-the-art motif…

Databases · Computer Science 2020-09-01 Michele Linardi , Yan Zhu , Themis Palpanas , Eamonn Keogh

Multiple Sequences Alignment (MSA) of biological sequences is a fundamental problem in computational biology due to its critical significance in wide ranging applications including haplotype reconstruction, sequence homology, phylogenetic…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-05-13 Fahad Saeed , Ashfaq Khokhar

Sequence classification has numerous applications in various fields. Despite extensive studies in the last decades, many challenges still exist, particularly in pattern-based methods. Existing pattern-based methods measure the…

Machine Learning · Computer Science 2023-10-23 Junjie Dong , Mudi Jiang , Lianyu Hu , Zengyou He

Inverse design of short single-stranded RNA and DNA sequences (aptamers) is the task of finding sequences that satisfy a set of desired criteria. Relevant criteria may be, for example, the presence of specific folding motifs, binding to…

Multiplexed imaging data are revolutionizing our understanding of the composition and organization of tissues and tumors. A critical aspect of such tissue profiling is quantifying the spatial relationship relationships among cells at…

Quantitative Methods · Quantitative Biology 2024-05-06 Ajit J. Nirmal , Peter K. Sorger

Diffusion models have achieved great success in image generation, with the backbone evolving from U-Net to Vision Transformers. However, the computational cost of Transformers is quadratic to the number of tokens, leading to significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Yao Teng , Yue Wu , Han Shi , Xuefei Ning , Guohao Dai , Yu Wang , Zhenguo Li , Xihui Liu

Deep sequencing has become one of the most popular tools for transcriptome profiling in biomedical studies. While an abundance of computational methods exists for "normalizing" sequencing data to remove unwanted between-sample variations…

Genomics · Quantitative Biology 2022-01-14 Yannick Düren , Johannes Lederer , Li-Xuan Qin

Generative model-based deep clustering frameworks excel in classifying complex data, but are limited in handling dynamic and complex features because they require prior knowledge of the number of clusters. In this paper, we propose a…

Machine Learning · Computer Science 2023-11-28 Zhenshan Bing , Yuan Meng , Yuqi Yun , Hang Su , Xiaojie Su , Kai Huang , Alois Knoll

DNA sequence alignment is important today as it is usually the first step in finding gene mutation, evolutionary similarities, protein structure, drug development and cancer treatment. Covid-19 is one recent example. There are many…

Genomics · Quantitative Biology 2023-06-01 Suchindra , Preetam Nagaraj

Network meta-analysis of diagnostic test accuracy (NMA-DTA) is a relatively new field, involving combining evidence across studies to evaluate and compare the accuracy of different tests for a given condition. However, the methods proposed…

Methodology · Statistics 2026-04-23 Efthymia Derezea , Gabriel Rogers , Nicky J Welton , Hayley E Jones

Ensuring reliable data collection in large-scale particle physics experiments demands Data Quality Monitoring (DQM) procedures to detect possible detector malfunctions and preserve data integrity. Traditionally, this resource-intensive task…

High Energy Physics - Experiment · Physics 2025-09-19 Arsenii Gavrikov , Julián García Pardiñas , Alberto Garfagnini