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Single-cell RNA-seq profiles are high-dimensional, sparse, and unordered, causing autoregressive generation to impose an artificial ordering bias and suffer from error accumulation. To address this, we propose scDiVa, a masked discrete…

Machine Learning · Computer Science 2026-02-04 Mingxuan Wang , Cheng Chen , Gaoyang Jiang , Zijia Ren , Chuangxin Zhao , Lu Shi , Yanbiao Ma

In recent developments, the Mamba architecture, known for its selective state space approach, has shown potential in the efficient modeling of long sequences. However, its application in image generation remains underexplored. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Shentong Mo , Yapeng Tian

Motivation: A considerable number of data mining approaches for biomedical data analysis, including state-of-the-art associative models, require a form of data discretization. Although diverse discretization approaches have been proposed,…

Quantitative Methods · Quantitative Biology 2021-03-09 Leonardo Alexandre , Rafael S. Costa , Rui Henriques

Difference image analysis (DIA) is a powerful tool for studying time-variable phenomena, and has been used by many time-domain surveys. Most DIA algorithms involve matching the spatially-varying PSF shape between science and template…

Determining molecular abundances in astrophysical environments is crucial for interpreting observational data and constraining physical conditions in these regions. Chemical modelling tools are essential for simulating the complex processes…

Instrumentation and Methods for Astrophysics · Physics 2025-09-17 Luke Keyte , Jason Ran

Contrastive Language-Image Pre-training (CLIP), which excels at abstracting open-world representations across domains and modalities, has become a foundation for a variety of vision and multimodal tasks. However, recent studies reveal that…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Wenxuan Wang , Quan Sun , Fan Zhang , Yepeng Tang , Jing Liu , Xinlong Wang

Summary: The DynaSig-ML (Dynamical Signatures - Machine Learning) Python package allows the efficient, user-friendly exploration of 3D dynamics-function relationships in biomolecules, using datasets of experimental measures from large…

Biomolecules · Quantitative Biology 2022-07-08 Olivier Mailhot , Francois Major , Rafael Najmanovich

A comprehensive analysis of viral mutations is essential for understanding viral evolution, disease epidemiology, diagnosis, drug resistance, etc. However, challenges remain in capturing complex mutation patterns and supporting diverse…

Quantitative Methods · Quantitative Biology 2026-04-24 Rui Wang , Xuhang Dai , Xin Cao , Changchuan Yin , Tamar Schlick , Guo-Wei Wei

Multiple Instance Learning (MIL) has emerged as a dominant paradigm to extract discriminative feature representations within Whole Slide Images (WSIs) in computational pathology. Despite driving notable progress, existing MIL approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Shu Yang , Yihui Wang , Hao Chen

Spatio-temporal video prediction plays a pivotal role in critical domains, ranging from weather forecasting to industrial automation. However, in high-precision industrial scenarios such as semiconductor manufacturing, the absence of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 Xinyu Xie , Weifeng Cao , Jun Shi , Yangyang Hu , Hui Liang , Wanyong Liang , Xiaoliang Qian

With the rapid spread of the novel coronavirus (COVID-19) across the globe and its continuous mutation, it is of pivotal importance to design a system to identify different known (and unknown) variants of SARS-CoV-2. Identifying particular…

Quantitative Methods · Quantitative Biology 2021-10-13 Sarwan Ali , Bikram Sahoo , Naimat Ullah , Alexander Zelikovskiy , Murray Patterson , Imdadullah Khan

Stream processing acceleration is driven by the continuously increasing volume and velocity of data generated on the Web and the limitations of storage, computation, and power consumption. Hardware solutions provide better performance and…

Databases · Computer Science 2024-08-29 Mohammadreza Najafi , Thamir M. Qadah , Mohammad Sadoghi , Hans-Arno Jacobsen

Mining data streams is a challenge per se. It must be ready to deal with an enormous amount of data and with problems not present in batch machine learning, such as concept drift. Therefore, applying a batch-designed technique, such as…

Machine Learning · Computer Science 2020-08-21 Lucca Portes Cavalheiro , Jean Paul Barddal , Alceu de Souza Britto , Laurent Heutte

Recent evidence suggests that analyzing the presence/absence of taxonomic features can offer a compelling alternative to differential abundance analysis in microbiome studies. However, standard approaches to differential prevalence analysis…

Methodology · Statistics 2026-05-26 Juho Pelto , Kari Auranen , Janne V. Kujala , Leo Lahti

Here we present a versatile foundation model that can perform a range of clinically-relevant image analysis tasks, including segmentation, landmark localisation, diagnosis, and prognostication. A multi-view convolution-transformer masked…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Yunguan Fu , Wenjia Bai , Weixi Yi , Charlotte Manisty , Anish N Bhuva , Thomas A Treibel , James C Moon , Matthew J Clarkson , Rhodri Huw Davies , Yipeng Hu

The automated segmentation of Intracranial Arteries (IA) in Digital Subtraction Angiography (DSA) plays a crucial role in the quantification of vascular morphology, significantly contributing to computer-assisted stroke research and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Wentao Liu , Tong Tian , Lemeng Wang , Weijin Xu , Lei Li , Haoyuan Li , Wenyi Zhao , Siyu Tian , Xipeng Pan , Huihua Yang , Feng Gao , Yiming Deng , Xin Yang , Ruisheng Su

Measures of similarity (or dissimilarity) are a key ingredient to many machine learning algorithms. We introduce DID, a pairwise dissimilarity measure applicable to a wide range of data spaces, which leverages the data's internal structure…

Machine Learning · Statistics 2022-03-08 Théophile Cantelobre , Carlo Ciliberto , Benjamin Guedj , Alessandro Rudi

Systems based on deep neural networks are vulnerable to adversarial attacks. Unrestricted adversarial attacks typically manipulate the semantic content of an image (e.g., color or texture) to create adversarial examples that are both…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Zihao Pan , Lifeng Chen , Weibin Wu , Yuhang Cao , Zibin Zheng

Deep learning has achieved great success in a wide spectrum of multimedia applications such as image classification, natural language processing and multimodal data analysis. Recent years have seen the development of many deep learning…

Machine Learning · Computer Science 2021-08-06 Naili Xing , Sai Ho Yeung , Chenghao Cai , Teck Khim Ng , Wei Wang , Kaiyuan Yang , Nan Yang , Meihui Zhang , Gang Chen , Beng Chin Ooi

Variant detection from high-throughput sequencing data is an essential step in identification of alleles involved in complex diseases and cancer. To deal with these massive data, elaborated sequence analysis pipelines are employed. A core…

Genomics · Quantitative Biology 2016-05-31 Karel Břinda , Valentina Boeva , Gregory Kucherov