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We study an optimal threshold functional arising in binary classification for continuous biomarkers. While the ROC curve summarizes discriminatory performance across all thresholds, practical threshold selection must also account for…

Methodology · Statistics 2026-05-11 Renato de Paula , Helena Mouriño , Tiago Dias Domingues

Time-dependent Receiver Operating Characteristics (ROC) analysis is a standard method to evaluate the discriminative performance of biomarkers or risk scores for time-to-event outcomes. Extensions of this useful method to left-truncated…

Methodology · Statistics 2025-09-09 Kendrick Li , Mithun Kumar Acharjee

The Area Under the ROC Curve (AUC) is a key metric for classification, especially under class imbalance, with growing research focus on optimizing AUC over accuracy in applications like medical image analysis and deepfake detection. This…

Machine Learning · Computer Science 2025-05-27 Mingyang Wu , Li Lin , Wenbin Zhang , Xin Wang , Zhenhuan Yang , Shu Hu

The area under the ROC curve (AUROC) has been vigorously applied for imbalanced classification and moreover combined with deep learning techniques. However, there is no existing work that provides sound information for peers to choose…

Machine Learning · Computer Science 2022-07-06 Dixian Zhu , Xiaodong Wu , Tianbao Yang

We develop a scoring and classification procedure based on the PAC-Bayesian approach and the AUC (Area Under Curve) criterion. We focus initially on the class of linear score functions. We derive PAC-Bayesian non-asymptotic bounds for two…

Machine Learning · Statistics 2014-10-14 James Ridgway , Pierre Alquier , Nicolas Chopin , Feng Liang

The ROC (receiver operating characteristic) curve is a widely used device for assessing decision-making systems. It seems surprising, in view of its history dating back to World War Two, that the assignment of uncertainties to a ROC curve…

Data Analysis, Statistics and Probability · Physics 2024-08-19 M. P. Fewell

The area under the curve (AUC) of summary receiver operating characteristic (SROC) curve is a primary statistical outcome for meta-analysis of diagnostic test accuracy studies (DTA). However, its confidence interval has not been reported in…

Applications · Statistics 2022-08-02 Hisashi Noma , Yuki Matsushima , Ryota Ishii

This article considers the receiver operating characteristic (ROC) curve analysis for medical data with non-ignorable missingness in the disease status. In the framework of the logistic regression models for both the disease status and the…

Methodology · Statistics 2024-11-27 Dingding Hu , Tao Yu , Pengfei Li

The performance of risk prediction models is often characterized in terms of discrimination and calibration. The Receiver Operating Characteristic (ROC) curve is widely used for evaluating model discrimination. When evaluating the…

Methodology · Statistics 2021-10-19 Mohsen Sadatsafavi , Paramita Saha-Chaudhuri , John Petkau

The Area Under the ROC Curve (AUC) is a widely used performance measure for imbalanced classification arising from many application domains where high-dimensional sparse data is abundant. In such cases, each $d$ dimensional sample has only…

Machine Learning · Computer Science 2020-09-24 Baojian Zhou , Yiming Ying , Steven Skiena

Many studies are devoted to the design of radiomic models for a prediction task. When no effective model is found, it is often difficult to know whether the radiomic features do not include information relevant to the task or because of…

Quantitative Methods · Quantitative Biology 2021-01-05 AS Dirand , F Frouin , I Buvat

The ROC curve is the major tool for assessing not only the performance but also the fairness properties of a similarity scoring function. In order to draw reliable conclusions based on empirical ROC analysis, accurately evaluating the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Jean-Rémy Conti , Stéphan Clémençon

The rise of smart factories has heightened the demand for automated maintenance, and normal-data-based anomaly detection has proved particularly effective in environments where anomaly data are scarce. This method, which does not require…

Machine Learning · Computer Science 2024-08-12 Wonjun Yi , Yong-Hwa Park , Wonho Jung

To assess the classification accuracy of a continuous diagnostic result, the receiver operating characteristic (ROC) curve is commonly used in applications. The partial area under the ROC curve (pAUC) is one of widely accepted summary…

Applications · Statistics 2011-03-11 Hung Hung , Chin-Tsang Chiang

The area under the ROC curve is widely used as a measure of performance of classification rules. However, it has recently been shown that the measure is fundamentally incoherent, in the sense that it treats the relative severities of…

Methodology · Statistics 2013-08-02 David J. Hand , Christoforos Anagnostopoulos

While the area under the ROC curve is perhaps the most common measure that is used to rank the relative performance of different binary classifiers, longstanding field folklore has noted that it can be a measure that ill-captures the…

Machine Learning · Computer Science 2024-12-19 Christopher Ratigan , Lenore Cowen

The comparison of Receiver Operating Characteristic (ROC) curves is frequently used in the literature to compare the discriminatory capability of different classification procedures based on diagnostic variables. The performance of these…

Many fields use the ROC curve and the PR curve as standard evaluations of binary classification methods. Analysis of ROC and PR, however, often gives misleading and inflated performance evaluations, especially with an imbalanced ground…

Machine Learning · Statistics 2020-06-23 Chang Cao , Davide Chicco , Michael M. Hoffman

Complex survey data are usually collected following complex sampling designs. Accounting for the sampling design is essential to obtain unbiased estimates and valid inferences when analyzing complex survey data. The area under the receiver…

Methodology · Statistics 2026-03-31 Amaia Iparragirre , Thomas Lumley , Irantzu Barrio

The ROC curve is widely used to assess binary classifiers. Yet for some applications, such as alert systems for monitoring hospitalized patients, conventional ROC analysis cannot meet two key deployment needs: enforcing a constraint on…

Machine Learning · Computer Science 2026-04-03 Christopher Ratigan , Kyle Heuton , Carissa Wang , Lenore Cowen , Michael C. Hughes
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