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Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

We propose In-Context Clustering (ICC), a flexible LLM-based procedure for clustering data from diverse distributions. Unlike traditional clustering algorithms constrained by predefined similarity measures, ICC flexibly captures complex…

Machine Learning · Computer Science 2025-10-10 Ying Wang , Mengye Ren , Andrew Gordon Wilson

Spatially-resolved omics-data enable researchers to precisely distinguish cell types in tissue and explore their spatial interactions, enabling deep understanding of tissue functionality. To understand what causes or deteriorates a disease…

Continual learning (CL) studies the problem of learning a sequence of tasks, one at a time, such that the learning of each new task does not lead to the deterioration in performance on the previously seen ones while exploiting previously…

Machine Learning · Computer Science 2020-11-03 Ammar Shaker , Francesco Alesiani , Shujian Yu , Wenzhe Yin

Co-clustering targets on grouping the samples (e.g., documents, users) and the features (e.g., words, ratings) simultaneously. It employs the dual relation and the bilateral information between the samples and features. In many realworld…

Machine Learning · Computer Science 2016-11-18 Ping Li , Jiajun Bu , Chun Chen , Zhanying He , Deng Cai

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Clustering multi-view data has been a fundamental research topic in the computer vision community. It has been shown that a better accuracy can be achieved by integrating information of all the views than just using one view individually.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Ming Yin , Weitian Huang , Junbin Gao

The plethora of single-cell multi-omics data is getting treatment with deep learning, a revolutionary method in artificial intelligence, which has been increasingly expanding its reign over the bioscience frontiers.

Other Quantitative Biology · Quantitative Biology 2019-03-12 A. K. M. Azad , Fatemeh Vafaee

Micro-panel data are collected and analysed in many research and industry areas. Cluster analysis of micro-panel data is an unsupervised learning exploratory method identifying subgroup clusters in a data set which include homogeneous…

Machine Learning · Statistics 2018-07-17 Lukas Sobisek , Maria Stachova , Jan Fojtik

Recent studies have demonstrated the effectiveness of clustering-based approaches for self-supervised and unsupervised learning. However, the application of clustering is often heuristic, and the optimal methodology remains unclear. In this…

Machine Learning · Computer Science 2025-11-10 Xiaodong Wang , Jing Huang , Kevin J Liang

Semi-supervised learning utilizes insights from unlabeled data to improve model generalization, thereby reducing reliance on large labeled datasets. Most existing studies focus on limited samples and fail to capture the overall data…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Xiuzhen Guo , Lianyuan Yu , Ji Shi , Na Lei , Hongxiao Wang

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

Incomplete multi-view clustering is an important technique to deal with real-world incomplete multi-view data. Previous works assume that all views have the same incompleteness, i.e., balanced incompleteness. However, different views often…

Machine Learning · Computer Science 2026-05-26 Xiang Fang , Yuchong Hu , Pan Zhou , Dapeng Oliver Wu

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Controlling false positives (Type I errors) through statistical hypothesis testing is a foundation of modern scientific data analysis. Existing causal structure discovery algorithms either do not provide Type I error control or cannot scale…

Methodology · Statistics 2025-12-29 James Leiner , Brian Manzo , Aaditya Ramdas , Wesley Tansey

Single-cell proteomics (SCP) is transforming our understanding of biological complexity by shifting from bulk proteomics, where signals are averaged over thousands of cells, to the proteome analysis of individual cells. This granular…

Quantitative Methods · Quantitative Biology 2025-04-01 Amanda Momenzadeh , Jesse G. Meyer

Semi-supervised learning (SSL) has made notable advancements in medical image segmentation (MIS), particularly in scenarios with limited labeled data and significantly enhancing data utilization efficiency. Previous methods primarily focus…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Mengzhu Wang , Jiao Li , Houcheng Su , Nan Yin , Liang Yang , Shen Li

Single-cell RNA sequencing (scRNA-seq) technology provides high-throughput gene expression data to study the cellular heterogeneity and dynamics of complex organisms. Graph neural networks (GNNs) have been widely used for automatic cell…

Machine Learning · Computer Science 2023-12-19 Rui Yang , Wenrui Dai , Chenglin Li , Junni Zou , Dapeng Wu , Hongkai Xiong

Scientific Machine Learning (SciML) is a recently emerged research field which combines physics-based and data-driven models for the numerical approximation of differential problems. Physics-based models rely on the physical understanding…

Numerical Analysis · Mathematics 2025-04-04 Alfio Quarteroni , Paola Gervasio , Francesco Regazzoni

Multi-view clustering has become a significant area of research, with numerous methods proposed over the past decades to enhance clustering accuracy. However, in many real-world applications, it is crucial to demonstrate a clear…

Machine Learning · Computer Science 2025-02-07 Mudi Jiang , Lianyu Hu , Zengyou He , Zhikui Chen