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Self-paced reinforcement learning (RL) aims to improve the data efficiency of learning by automatically creating sequences, namely curricula, of probability distributions over contexts. However, existing techniques for self-paced RL fail in…

Machine Learning · Computer Science 2023-05-29 Cevahir Koprulu , Ufuk Topcu

We present a Transfer Causal Learning (TCL) framework when target and source domains share the same covariate/feature spaces, aiming to improve causal effect estimation accuracy in limited data. Limited data is very common in medical…

Machine Learning · Computer Science 2024-01-02 Song Wei , Hanyu Zhang , Ronald Moore , Rishikesan Kamaleswaran , Yao Xie

The integration of Large Language Models (LLMs) into clinical decision support is critically obstructed by their opaque and often unreliable reasoning. In the high-stakes domain of healthcare, correct answers alone are insufficient;…

Artificial Intelligence · Computer Science 2026-04-21 Chen Zhan , Xiaoyu Tan , Gengchen Ma , Yu-Jie Xiong , Xiaoyan Jiang , Xihe Qiu

Real-world data, such as administrative claims and electronic health records, are increasingly used for safety monitoring and to help guide regulatory decision-making. In these settings, it is important to document analytic decisions…

When the available data for a target domain is limited, transfer learning (TL) methods can be used to develop models on related data-rich domains, before deploying them on the target domain. However, these TL methods are typically designed…

Statistical Finance · Quantitative Finance 2025-08-06 Ricardo Ribeiro Pereira , Jacopo Bono , Hugo Ferreira , Pedro Ribeiro , Carlos Soares , Pedro Bizarro

Tabular data serves as the backbone of modern data analysis and scientific research. While Large Language Models (LLMs) fine-tuned via Supervised Fine-Tuning (SFT) have significantly improved natural language interaction with such…

Estimating individualized treatment rules (ITRs) is fundamental to precision medicine, where the goal is to tailor treatment decisions to individual patient characteristics. While numerous methods have been developed for ITR estimation,…

Methodology · Statistics 2026-05-15 Eun Jeong Oh , Min Qian

LLM-based relevance judgment generation has become a crucial approach in advancing evaluation methodologies in Information Retrieval (IR). It has progressed significantly, often showing high correlation with human judgments as reflected in…

Information Retrieval · Computer Science 2026-01-13 Mouly Dewan , Jiqun Liu , Chirag Shah

Electronic health record (EHR) data are increasingly used to support real-world evidence (RWE) studies. Yet its ability to generate reliable RWE is limited by the lack of readily available precise information on the timing of clinical…

Humanoid table tennis (TT) demands rapid perception, proactive whole-body motion, and agile footwork under strict timing--capabilities that remain difficult for end-to-end control policies. We propose a reinforcement learning (RL) framework…

Knowledge tracing (KT), aiming to mine students' mastery of knowledge by their exercise records and predict their performance on future test questions, is a critical task in educational assessment. While researchers achieved tremendous…

Artificial Intelligence · Computer Science 2024-05-28 Haoxuan Li , Jifan Yu , Yuanxin Ouyang , Zhuang Liu , Wenge Rong , Juanzi Li , Zhang Xiong

The integration of real-world data (RWD) and randomized controlled trials (RCT) is increasingly important for advancing causal inference in scientific research. This combination holds great promise for enhancing the efficiency of causal…

Methodology · Statistics 2024-07-02 Xi Lin , Jens Magelund Tarp , Robin J. Evans

The Targeted Maximum Likelihood Estimation (TMLE) statistical data analysis framework integrates machine learning, statistical theory, and statistical inference to provide a least biased, efficient and robust strategy for estimation and…

Error detection (ED), which aims to identify incorrect or inconsistent cell values in tabular data, is important for ensuring data quality. Recent state-of-the-art ED methods leverage the pre-trained knowledge and semantic capability…

Computation and Language · Computer Science 2025-12-09 Mengqi Wang , Jianwei Wang , Qing Liu , Xiwei Xu , Zhenchang Xing , Liming Zhu , Wenjie Zhang

In this paper, we study the Tiered Reinforcement Learning setting, a parallel transfer learning framework, where the goal is to transfer knowledge from the low-tier (source) task to the high-tier (target) task to reduce the exploration risk…

Machine Learning · Computer Science 2024-06-14 Jiawei Huang , Niao He

In pharmaceutical R&D, predicting the efficacy of a pharmaceutical in treating a particular disease prior to clinical testing or any real-world use has been challenging. In this paper, we propose a flexible and modular machine…

Machine Learning · Computer Science 2025-09-10 Adrien Couetoux , Thomas Devenyns , Lise Diagne , David Champagne , Pierre-Yves Mousset , Chris Anagnostopoulos

Medical treatments often involve a sequence of decisions, each informed by previous outcomes. This process closely aligns with reinforcement learning (RL), a framework for optimizing sequential decisions to maximize cumulative rewards under…

Machine Learning · Computer Science 2024-10-15 Ali Shirali , Alexander Schubert , Ahmed Alaa

Retrieval-Augmented Generation (RAG) delivers substantial value in knowledge-intensive applications. However, its generated responses often lack transparent reasoning paths that trace back to source evidence from retrieved documents. This…

Computation and Language · Computer Science 2026-01-30 Jingyi Ren , Yekun Xu , Xiaolong Wang , Weitao Li , Ante Wang , Weizhi Ma , Yang Liu

Temporal difference learning (TD) is a foundational concept in reinforcement learning (RL), aimed at efficiently assessing a policy's value function. TD($\lambda$), a potent variant, incorporates a memory trace to distribute the prediction…

Machine Learning · Computer Science 2024-02-13 Jianfei Ma

Large language models (LLMs) are increasingly used to extract clinical data from electronic health records (EHRs), offering significant improvements in scalability and efficiency for real-world data (RWD) curation in oncology. However, the…

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