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Reinforcement learning (RL) can be formulated as a sequence modeling problem, where models predict future actions based on historical state-action-reward sequences. Current approaches typically require long trajectory sequences to model the…
Previous LLMs-based RL studies typically follow either supervised learning with high annotation costs, or unsupervised paradigms using voting or entropy-based rewards. However, their performance remains far from satisfactory due to the…
Machine learning for wireless systems is commonly studied using standardized stochastic channel models (e.g., TDL/CDL/UMa) because of their legacy in wireless communication standardization and their ability to generate data at scale.…
The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…
Traditional Reinforcement Learning (RL) has focused on problems involving many states and few actions, such as simple grid worlds. Most real world problems, however, are of the opposite type, Involving Few relevant states and many actions.…
Model-free reinforcement learning (RL) is a powerful, general tool for learning complex behaviors. However, its sample efficiency is often impractically large for solving challenging real-world problems, even with off-policy algorithms such…
Prediction for ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) plays a crucial role in drug discovery and development, accelerating the screening and optimization of new drugs. Existing methods primarily rely on…
Deep graph learning has achieved remarkable progresses in both business and scientific areas ranging from finance and e-commerce, to drug and advanced material discovery. Despite these progresses, how to ensure various deep graph learning…
Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical images, particularly fundus images, remains costly and…
Phase I dose-finding trials are increasingly challenging as the relationship between efficacy and toxicity of new compounds (or combination of them) becomes more complex. Despite this, most commonly used methods in practice focus on…
The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…
There is an increasing interest in ensuring machine learning (ML) frameworks behave in a socially responsible manner and are deemed trustworthy. Although considerable progress has been made in the field of Trustworthy ML (TwML) in the…
Reinforcement learning (RL) in the real world necessitates the development of procedures that enable agents to explore without causing harm to themselves or others. The most successful solutions to the problem of safe RL leverage offline…
Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…
In recent years, the field of precision medicine has seen many advancements. Significant focus has been placed on creating algorithms to estimate individualized treatment rules (ITR), which map from patient covariates to the space of…
Over the last decade, the use of machine learning (ML) approaches in medicinal applications has increased manifold. Most of these approaches are based on deep learning, which aims to learn representations from grid data (like medical…
We consider the challenging problem of using domain knowledge to improve deep reinforcement learning policies. To this end, we propose LEGIBLE, a novel approach, following a multi-step process, which starts by mining rules from a deep RL…
Reinforcement Learning (RL) applications in real-world scenarios must prioritize safety and reliability, which impose strict constraints on agent behavior. Model-based RL leverages predictive world models for action planning and policy…
Reinforcement learning (RL) has been successfully used to solve many continuous control tasks. Despite its impressive results however, fundamental questions regarding the sample complexity of RL on continuous problems remain open. We study…
Ensuring that reinforcement learning (RL) controllers satisfy safety and reliability constraints in real-world settings remains challenging: state-avoidance and constrained Markov decision processes often fail to capture trajectory-level…