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Reinforcement learning (RL) can be formulated as a sequence modeling problem, where models predict future actions based on historical state-action-reward sequences. Current approaches typically require long trajectory sequences to model the…

Machine Learning · Computer Science 2024-12-23 Hemant Kumawat , Saibal Mukhopadhyay

Previous LLMs-based RL studies typically follow either supervised learning with high annotation costs, or unsupervised paradigms using voting or entropy-based rewards. However, their performance remains far from satisfactory due to the…

Machine Learning · Computer Science 2026-04-22 Zhiyin Yu , Bo Zhang , Qibin Hou , Zhonghai Wu , Xiao Luo , Lei Bai

Machine learning for wireless systems is commonly studied using standardized stochastic channel models (e.g., TDL/CDL/UMa) because of their legacy in wireless communication standardization and their ability to generate data at scale.…

Signal Processing · Electrical Eng. & Systems 2025-12-16 João Morais , Akshay Malhotra , Shahab Hamidi-Rad , Ahmed Alkhateeb

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Traditional Reinforcement Learning (RL) has focused on problems involving many states and few actions, such as simple grid worlds. Most real world problems, however, are of the opposite type, Involving Few relevant states and many actions.…

Machine Learning · Computer Science 2012-01-04 Vincent Graziano , Faustino Gomez , Mark Ring , Juergen Schmidhuber

Model-free reinforcement learning (RL) is a powerful, general tool for learning complex behaviors. However, its sample efficiency is often impractically large for solving challenging real-world problems, even with off-policy algorithms such…

Machine Learning · Computer Science 2020-02-25 Vitchyr Pong , Shixiang Gu , Murtaza Dalal , Sergey Levine

Prediction for ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) plays a crucial role in drug discovery and development, accelerating the screening and optimization of new drugs. Existing methods primarily rely on…

Machine Learning · Computer Science 2025-09-08 Han Zhang , Fengji Ma , Jiamin Su , Xinyue Yang , Lei Wang , Wen-Cai Ye , Li Liu

Deep graph learning has achieved remarkable progresses in both business and scientific areas ranging from finance and e-commerce, to drug and advanced material discovery. Despite these progresses, how to ensure various deep graph learning…

Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical images, particularly fundus images, remains costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Xi Luo , Shixin Xu , Ying Xie , JianZhong Hu , Yuwei He , Yuhui Deng , Huaxiong Huang

Phase I dose-finding trials are increasingly challenging as the relationship between efficacy and toxicity of new compounds (or combination of them) becomes more complex. Despite this, most commonly used methods in practice focus on…

Machine Learning · Computer Science 2020-06-16 Cong Shen , Zhiyang Wang , Sofia S. Villar , Mihaela van der Schaar

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

There is an increasing interest in ensuring machine learning (ML) frameworks behave in a socially responsible manner and are deemed trustworthy. Although considerable progress has been made in the field of Trustworthy ML (TwML) in the…

Social and Information Networks · Computer Science 2022-06-22 Noemi Derzsy , Subhabrata Majumdar , Rajat Malik

Reinforcement learning (RL) in the real world necessitates the development of procedures that enable agents to explore without causing harm to themselves or others. The most successful solutions to the problem of safe RL leverage offline…

Machine Learning · Computer Science 2025-01-09 Alexander Quessy , Thomas Richardson , Sebastian East

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

Machine Learning · Computer Science 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

In recent years, the field of precision medicine has seen many advancements. Significant focus has been placed on creating algorithms to estimate individualized treatment rules (ITR), which map from patient covariates to the space of…

Methodology · Statistics 2021-12-09 Kushal S. Shah , Haoda Fu , Michael R. Kosorok

Over the last decade, the use of machine learning (ML) approaches in medicinal applications has increased manifold. Most of these approaches are based on deep learning, which aims to learn representations from grid data (like medical…

Image and Video Processing · Electrical Eng. & Systems 2025-02-24 Maha Ezzelarab , Midhila Madhusoodanan , Shrimanti Ghosh , Geetika Vadali , Jacob Jaremko , Abhilash Hareendranathan

We consider the challenging problem of using domain knowledge to improve deep reinforcement learning policies. To this end, we propose LEGIBLE, a novel approach, following a multi-step process, which starts by mining rules from a deep RL…

Machine Learning · Computer Science 2025-03-13 Martin Tappler , Ignacio D. Lopez-Miguel , Sebastian Tschiatschek , Ezio Bartocci

Reinforcement Learning (RL) applications in real-world scenarios must prioritize safety and reliability, which impose strict constraints on agent behavior. Model-based RL leverages predictive world models for action planning and policy…

Artificial Intelligence · Computer Science 2025-06-06 Artem Latyshev , Gregory Gorbov , Aleksandr I. Panov

Reinforcement learning (RL) has been successfully used to solve many continuous control tasks. Despite its impressive results however, fundamental questions regarding the sample complexity of RL on continuous problems remain open. We study…

Machine Learning · Computer Science 2017-12-27 Stephen Tu , Benjamin Recht

Ensuring that reinforcement learning (RL) controllers satisfy safety and reliability constraints in real-world settings remains challenging: state-avoidance and constrained Markov decision processes often fail to capture trajectory-level…

Machine Learning · Computer Science 2026-04-06 Alper Kamil Bozkurt , Calin Belta , Ming C. Lin
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