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Purpose: The purpose of this study was to observe change in accuracies of convolutional neural networks (CNN) models (ratio of correct classifications to total predictions) on thoracic radiological images by creating different binary…

Image and Video Processing · Electrical Eng. & Systems 2019-12-03 Mir Muhammad Abdullah , Mir Muhammad Abdur Rahman , Mir Mohammed Assadullah

Due to its predominantly asymptomatic or mildly symptomatic progression, lung cancer is often diagnosed in advanced stages, resulting in poorer survival rates for patients. As with other cancers, early detection significantly improves the…

Tumors are extremely heterogeneous and comprise of a number of intratumor microenvironments or sub-regions. These tumor microenvironments may interact with eac based on complex high-level relationships, which could provide important insight…

Quantitative Methods · Quantitative Biology 2019-01-29 Vishwa S. Parekh , Michael A. Jacobs

Accurate interpretation of knee MRI scans relies on expert clinical judgment, often with high variability and limited scalability. Existing radiomic approaches use a fixed set of radiomic features (the signature), selected at the population…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Yaxi Chen , Simin Ni , Shaheer U. Saeed , Aleksandra Ivanova , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

Accurately predicting the treatment outcome plays a greatly important role in tailoring and adapting a treatment planning in cancer therapy. Although the development of different modalities and personalized medicine can greatly improve the…

We describe a visual computing approach to radiation therapy (RT) planning, based on spatial similarity within a patient cohort. In radiotherapy for head and neck cancer treatment, dosage to organs at risk surrounding a tumor is a large…

Medical Physics · Physics 2019-10-14 A. Wentzel , P. Hanula , T. Luciani , B. Elgohari , H. Elhalawani , G. Canahuate , D. Vock , C. D. Fuller , G. E. Marai

Purpose: CBCT-based adaptive radiotherapy requires daily images for accurate dose calculations. This study investigates the feasibility of applying a single convolutional network to facilitate CBCT-to-CT synthesis for head-and-neck, lung,…

Human readers or radiologists routinely perform full-body multi-organ multi-disease detection and diagnosis in clinical practice, while most medical AI systems are built to focus on single organs with a narrow list of a few diseases. This…

Glioblastoma is the most malignant type of central nervous system tumor with GBM subtypes cleaved based on molecular level gene alterations. These alterations are also happened to affect the histology. Thus, it can cause visible changes in…

Quantitative Methods · Quantitative Biology 2020-10-28 Navodini Wijethilake , Mobarakol Islam , Dulani Meedeniya , Charith Chitraranjan , Indika Perera , Hongliang Ren

Planning of radiotherapy involves accurate segmentation of a large number of organs at risk, i.e. organs for which irradiation doses should be minimized to avoid important side effects of the therapy. We propose a deep learning method for…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Pawel Mlynarski , Hervé Delingette , Hamza Alghamdi , Pierre-Yves Bondiau , Nicholas Ayache

This pilot study compares per-lesion radiomics features of [68Ga]-DOTA FAPI-46 and [18F]-FDG PET/CT in non-small cell lung cancer (NSCLC) to explore complementary insights into intratumoral heterogeneity beyond conventional SUV metrics,…

Radiomics and deep learning both offer powerful tools for quantitative medical imaging, but most existing fusion approaches only leverage global radiomic features and overlook the complementary value of spatially resolved radiomic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Zengtian Deng , Yimeng He , Yu Shi , Lixia Wang , Touseef Ahmad Qureshi , Xiuzhen Huang , Debiao Li

Reliable segmentation of anatomical tissues of human head is a major step in several clinical applications such as brain mapping, surgery planning and associated computational simulation studies. Segmentation is based on identifying…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Essam A. Rashed , Mohammad al-Shatouri , Ilkka Laakso , Akimasa Hirata

Introduction: Tuberculous meningitis (TBM) is a serious brain infection caused by Mycobacterium tuberculosis, characterized by inflammation of the meninges covering the brain and spinal cord. Diagnosis often requires invasive lumbar…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Snigdha Agarwal , Ganaraja V H , Neelam Sinha , Abhilasha Indoria , Netravathi M , Jitender Saini

Purpose: Tumor-associated vasculature differs from healthy blood vessels by its chaotic architecture and twistedness, which promotes treatment resistance. Measurable differences in these attributes may help stratify patients by likely…

The thalamus is a subcortical structure of central importance to brain function, which is organized in smaller nuclei with specialized roles. Despite significant functional and clinical relevance, locating and distinguishing the different…

Prostate cancer is the most diagnosed form of cancer in Canadian men, and is the third leading cause of cancer death. Despite these statistics, prognosis is relatively good with a sufficiently early diagnosis, making fast and reliable…

Computer Vision and Pattern Recognition · Computer Science 2015-10-21 Audrey G. Chung , Mohammad Javad Shafiee , Devinder Kumar , Farzad Khalvati , Masoom A. Haider , Alexander Wong

The superior soft tissue differentiation provided by MRI may enable more accurate tumor segmentation compared to CT and PET, potentially enhancing adaptive radiotherapy treatment planning. The Head and Neck Tumor Segmentation for MR-Guided…

Introduction: Lung cancer is a leading cause of cancer-related mortality, and stereotactic body radiotherapy (SBRT) has become a standard treatment for early-stage lung cancer. However, the heterogeneous response to radiation at the tumor…

The inherent characteristics of lung tissues, which are independent of breathing manoeuvre, may provide fundamental information on lung function. This paper attempted to study function-correlated lung textures and their spatial distribution…

Medical Physics · Physics 2024-03-28 Yu-Hua Huang , Xinzhi Teng , Jiang Zhang , Zhi Chen , Zongrui Ma , Ge Ren , Feng-Ming , Kong , Jing Cai