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Purpose: Convolutional neural networks (CNNs) are promising in predicting treatment outcome for pediatric craniopharyngioma while the decision mechanisms are difficult to interpret. We compared the activation maps of CNN with hand crafted…

Medical Physics · Physics 2025-09-26 Wenjun Yang , Chuang Wang , Tina Davis , Jinsoo Uh , Chia-Ho Hua , Thomas E. Merchant

'Radiomics' is a method that extracts mineable quantitative features from radiographic images. These features can then be used to determine prognosis, for example, predicting the development of distant metastases (DM). Existing radiomics…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Yige Peng , Lei Bi , Michael Fulham , Dagan Feng , Jinman Kim

Chest x-rays are the most common radiology studies for diagnosing lung and heart disease. Hence, a system for automated pre-reporting of pathologic findings on chest x-rays would greatly enhance radiologists' productivity. To this end, we…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 Adora M. DSouza , Anas Z. Abidin , Axel Wismüller

Background: We aim to develop enriched radiomics features that integrate classical structural radiomics with novel functional radiomics derived from liver MRI for diagnosis and risk stratification in liver cancer. The proposed framework…

Methods: Our deep learning model, called AnatomyNet, segments OARs from head and neck CT images in an end-to-end fashion, receiving whole-volume HaN CT images as input and generating masks of all OARs of interest in one shot. AnatomyNet is…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Wentao Zhu , Yufang Huang , Liang Zeng , Xuming Chen , Yong Liu , Zhen Qian , Nan Du , Wei Fan , Xiaohui Xie

This study leverages graph neural networks to integrate MELC data with Radiomic-extracted features for melanoma classification, focusing on cell-wise analysis. It assesses the effectiveness of gene expression profiles and Radiomic features,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Luis Carlos Rivera Monroy , Leonhard Rist , Martin Eberhardt , Christian Ostalecki , Andreas Bauer , Julio Vera , Katharina Breininger , Andreas Maier

Objective: Deep Learning-based Radiomics (DLR) has achieved great success in medical image analysis and has been considered a replacement for conventional radiomics that relies on handcrafted features. In this study, we aimed to explore the…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Bingxin Gu , Mingyuan Meng , Lei Bi , Jinman Kim , David Dagan Feng , Shaoli Song

Aim: In the present work, we aimed to evaluate a comprehensive radiomics framework that enabled prediction of EGFR and KRAS mutation status in NSCLC cancer patients based on PET and CT multi-modalities radiomic features and machine learning…

Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Hao Li , Zeyu Tang , Yang Nan , Guang Yang

Accurate brain tumor typing requires integrating heterogeneous clinical evidence, including magnetic resonance imaging (MRI), histopathology, and pathology reports, which are often incomplete at the time of diagnosis. We introduce CoRe-BT,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Juampablo E. Heras Rivera , Daniel K. Low , Xavier Xiong , Jacob J. Ruzevick , Daniel D. Child , Wen-wai Yim , Mehmet Kurt , Asma Ben Abacha

Accurate three-dimensional delineation of liver tumors on contrast-enhanced CT is a prerequisite for treatment planning, navigation and response assessment, yet manual contouring is slow, observer-dependent and difficult to standardise…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Xuecheng Li , Weikuan Jia , Komildzhon Sharipov , Alimov Ruslan , Lutfuloev Mazbutdzhon , Ismoilov Shuhratjon , Yuanjie Zheng

Image features need to be robust against differences in positioning, acquisition and segmentation to ensure reproducibility. Radiomic models that only include robust features can be used to analyse new images, whereas models with non-robust…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Alex Zwanenburg , Stefan Leger , Linda Agolli , Karoline Pilz , Esther G. C. Troost , Christian Richter , Steffen Löck

Computer aided diagnosis (CAD) of Breast Cancer (BRCA) images has been an active area of research in recent years. The main goals of this research is to develop reliable automatic methods for detecting and diagnosing different types of BRCA…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Marco A. V. M. Grinet , Nuno M. Garcia , Ana I. R. Gouveia , Jose A. F. Moutinho , Abel J. P. Gomes

Artificial intelligence (AI) enabled radiomics has evolved immensely especially in the field of oncology. Radiomics provide assistancein diagnosis of cancer, planning of treatment strategy, and predictionof survival. Radiomics in…

Image and Video Processing · Electrical Eng. & Systems 2019-10-17 Syed Muhammad Anwar , Tooba Altaf , Khola Rafique , Harish RaviPrakash , Hassan Mohy-ud-Din , Ulas Bagci

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

Lung cancer is the leading cause of cancer death in the world. Accurate determination of the EGFR (epidermal growth factor receptor) mutation status is highly relevant for the proper treatment of this patients. Purpose: The aim of this…

Quantitative Methods · Quantitative Biology 2023-03-16 Hector Henriquez , Diana Fuentes , Francisco Suarez , Patricio Gonzalez

Although the combined treatment of surgery, radiotherapy, chemotherapy, and emerging target therapy has significantly improved the outcomes of patients with head and neck cancer, distant metastasis remains the leading cause of treatment…

Quantitative Methods · Quantitative Biology 2025-12-02 Nuo Tong , Changhao Liu , Zizhao Tang , Feifan Sun , Yingping Li , Shuiping Gou , Mei Shi

Manual delineation of volumes of interest (VOIs) by experts is considered the gold-standard method in radiomics analysis. However, it suffers from inter- and intra-operator variability. A quantitative assessment of the impact of variations…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Sepideh Hatamikia , Geevarghese George , Florian Schwarzhans , Amirreza Mahbod , Ramona Woitek

Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted…

The rapid proliferation of open-source medical foundation models (FMs) raises a practical question: how well do their pre-trained representations transfer to clinically relevant but data-scarce classification tasks? Particularly in CT-based…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Hartmut Häntze , Sarah de Boer , Myrthe Buser , Alessa Hering , Bram van Ginneken , Mathias Prokop , Jawed Nawabi , Sebastian Ziegelmayer , Lisa Adams , Keno Bressem
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