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Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires substantial compression of the normal B form…

Biomolecules · Quantitative Biology 2010-12-13 Debabrata Panja , Ian J. Molineux

Viruses like influenza have long coevolved with host immune systems, gradually shaping the evolutionary trajectory of these pathogens. Host immune systems develop immunity against circulating strains, which in turn avoid extinction by…

A critical step in the bacteriophage life cycle is genome ejection into host bacteria. The ejection process for double-stranded DNA phages has been studied thoroughly \textit{in vitro}, where after triggering with the cellular receptor the…

Biological Physics · Physics 2015-06-05 Serge G. Lemay , Debabrata Panja , Ian J. Molineux

Microbiomes are complex systems comprised of many interacting species. Species can survive harsh or changing conditions by rapid adaptation, a process accelerated by the exchange of genetic material between different species through…

Populations and Evolution · Quantitative Biology 2025-09-04 Johannes Nauta , Kaitlin A. Schaal , Ying-Jie Wang , James P. J. Hall , Shai Pilosof , Manlio De Domenico

Antipredator behavior is present in many biological systems where individuals collectively react to an imminent attack. The antipredator response may influence spatial pattern formation and ecosystem stability but requires an organism's…

Populations and Evolution · Quantitative Biology 2021-11-10 J. Menezes , B. Moura

Biopolymers are vital structures for many living organisms; for a variety of bacteria, adhesion polymers play a crucial role for the initiation of colonization. Some bacteria express, on their surface, attachment organelles (pili) that…

Biological Physics · Physics 2014-12-01 Johan Zakrisson , Krister Wiklund , Ove Axner , Magnus Andersson

The emergence of the phenomenon known as ABR (anti-bacterial resistance), is the result of the gradual decrease in the efficacy of antibiotics and the increase in the cost of producing new antibiotics. Hence, alternative solutions to…

Populations and Evolution · Quantitative Biology 2024-02-08 Nouf Alghamdi , Mal Horsburgh , Bakhtier Vasiev

Viral fibers play a central role in many virus infection mechanisms since they recognize the corresponding host and establish a mechanical link to its surface. Specifically, bacteriophages have to anchor to bacteria through the fibers…

Giant viruses contain large genomes, encode many proteins atypical for viruses, replicate in large viral factories, and tend to infect protists. The giant virus replication factories can in turn be infected by so called virophages, which…

Populations and Evolution · Quantitative Biology 2013-01-28 Dominik Wodarz

The ladybird $\textit{Eriopis connexa}$ (Germar, 1824), a voracious aphid predator, faces challenges from insecticide applications, compromising biological control. As a result, there has been an increase in the number of studies analysing…

The striking variety of macroscopic morphologies displayed by bacterial colonies depends on microscopic environmental and behavioural details in a manner that is currently not well understood. A surprising example is sibling inhibition,…

Cell Behavior · Quantitative Biology 2026-05-15 Dario Buonomo , Francesco Imperi , Fabio Bruni , Marco Polin , Barbara Capone

Bacteria and their viruses ("bacteriophages") coexist in natural environments forming complex infection networks. Recent empirical findings suggest that phage-bacteria infection networks often possess a nested structure such that there is a…

Populations and Evolution · Quantitative Biology 2013-04-09 Luis F. Jover , Michael H. Cortez , Joshua S. Weitz

Understanding how a diversity of plants in agroecosystems affects the adaptation of pathogens in a key issue in agroecology. We analyze PDE systems describing the dynamics of adaptation of two phenotypically structured populations, under…

Analysis of PDEs · Mathematics 2021-03-08 François Hamel , Florian Lavigne , Lionel Roques

Bacteria and their bacteriophages are the most abundant, widespread and diverse groups of biological entities on the planet. In an attempt to understand how the interactions between bacteria, virulent phages and temperate phages might…

Populations and Evolution · Quantitative Biology 2009-11-13 Martin Rosvall , Ian B. Dodd , Sandeep Krishna , Kim Sneppen

Co-infecting parasites and pathogens remain a leading challenge for global public health due to their consequences for individual-level infection risk and disease progression. However, a clear understanding of the population-level…

Populations and Evolution · Quantitative Biology 2017-12-05 Erin E. Gorsich , Rampal S. Etienne , Jan Medlock , Brianna R. Beechler , Johannie M. Spaan , Robert S. Spaan , Vanessa O. Ezenwa , Anna E. Jolles

Network ecology is a rising field of quantitative biology representing ecosystems as complex networks. A suitable example is parasite spreading: several parasites may be transmitted among their hosts through different mechanisms, each one…

Quantitative Methods · Quantitative Biology 2016-09-12 Massimo Stella , Cecilia S. Andreazzi , Sanja Selakovic , Alireza Goudarzi , Alberto Antonioni

Single molecule experiments on bacteriophages show an exponential scaling for the dependence of mobility on the length of DNA within the capsid. It has been suggested that this could be due to the "capstan mechanism" -- the exponential…

Biological Physics · Physics 2017-05-31 Rahul Arun , Sandip Ghosal

Spatial extent is a complicating factor in mathematical biology. The possibility that an action at point A cannot immediately affect what happens at point B creates the opportunity for spatial nonuniformity. This nonuniformity must change…

Cellular Automata and Lattice Gases · Physics 2014-01-03 Blake C. Stacey , Andreas Gros , Yaneer Bar-Yam

The anisotropy of a trap potential can impact the density and variance of a Bose-Einstein condensate (BEC) in an opposite manner. We exemplify this effect for both the ground state and out-of-equilibrium dynamics of structureless bosons…

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