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Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Maria Frasca , Davide La Torre , Gabriella Pravettoni , Ilaria Cutica

Parkinsons disease is the second most prevalent neurodegenerative disorder with over ten million active cases worldwide and one million new diagnoses per year. Detecting and subsequently diagnosing the disease is challenging because of…

Computation and Language · Computer Science 2024-04-09 Jonathan Crawford

Parkinson's Disease (PD) is a progressive nervous system disorder that has affected more than 5.8 million people, especially the elderly. Due to the complexity of its symptoms and its similarity to other neurological disorders, early…

Artificial Intelligence · Computer Science 2022-11-29 Jingwei Li , Ruitian Wu , Tzu-liang Huang , Zian Pan , Ming-chun Huang

Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…

Signal Processing · Electrical Eng. & Systems 2019-11-26 Vyom Raval , Kevin P. Nguyen , Ashley Gerald , Richard B. Dewey , Albert Montillo

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

Machine Learning · Computer Science 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

Motor dysfunction is a common sign of neurodegenerative diseases (NDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD), but may be difficult to detect, especially in the early stages. In this work, we examine the behavior of a…

Neurons and Cognition · Quantitative Biology 2025-10-23 Thomas Thebaud , Anna Favaro , Casey Chen , Gabrielle Chavez , Laureano Moro-Velazquez , Ankur Butala , Najim Dehak

In the world, about 7 to 10 million elderly people are suffering from Parkinson's Disease (PD) disease. Parkinson's disease is a common neurological degenerative disease, and its clinical characteristics are Tremors, rigidity, bradykinesia,…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Elcin Huseyn

Parkinsons Disease is a neurological disorder and prevalent in elderly people. Traditional ways to diagnose the disease rely on in-person subjective clinical evaluations on the quality of a set of activity tests. The high-resolution…

Machine Learning · Computer Science 2020-10-16 Weijian Li , Wei Zhu , E. Ray Dorsey , Jiebo Luo

Parkinson's Disease (PD) is one of the most common types of neurological diseases caused by progressive degeneration of dopamin- ergic neurons in the brain. Even though there is no fixed cure for this neurodegenerative disease, earlier…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Sara Soltaninejad , Irene Cheng , Anup Basu

One of the symptoms observed in the early stages of Parkinson's Disease (PD) is speech impairment. Speech disorders can be used to detect this disease before it degenerates. This work analyzes speech features and machine learning approaches…

Audio and Speech Processing · Electrical Eng. & Systems 2021-11-22 Adedolapo Aishat Toye , Suryaprakash Kompalli

Parkinson's Disease (PD) is characterized by disorders in motor function such as freezing of gait, rest tremor, rigidity, and slowed and hyposcaled movements. Medication with dopaminergic medication may alleviate those motor symptoms,…

Computer Vision and Pattern Recognition · Computer Science 2018-08-09 Terry Taewoong Um , Franz Michael Josef Pfister , Daniel Christian Pichler , Satoshi Endo , Muriel Lang , Sandra Hirche , Urban Fietzek , Dana Kulić

People with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring the progression of the disease through a…

Audio and Speech Processing · Electrical Eng. & Systems 2022-05-25 Mohammadreza Iman , Amy Giuntini , Hamid Reza Arabnia , Khaled Rasheed

One of the symptoms of Parkinson's disease (PD) is hypomimia or reduced facial expressions. In this paper, we present a digital biomarker for PD that utilizes the study of micro-expressions. We analyzed the facial action units (AU) from…

Human-Computer Interaction · Computer Science 2021-09-06 Mohammad Rafayet Ali , Taylor Myers , Ellen Wagner , Harshil Ratnu , E. Ray Dorsey , Ehsan Hoque

Speech disorders often occur at the early stage of Parkinson's disease (PD). The speech impairments could be indicators of the disorder for early diagnosis, while motor symptoms are not obvious. In this study, we constructed a new speech…

Audio and Speech Processing · Electrical Eng. & Systems 2021-06-01 Hao Fang , Chen Gong , Chen Zhang , Yanan Sui , Luming Li

Parkinson's disease (PD) is a common and complex neurodegenerative disorder with 5 stages in the Hoehn and Yahr scaling. Given the heterogeneity of PD, it is challenging to classify early stages 1 and 2 and detect brain function…

Neurons and Cognition · Quantitative Biology 2022-07-22 Xueqi Guo , Sule Tinaz , Nicha C. Dvornek

Parkinson's disease (PD) is commonly characterized by several motor symptoms, such as bradykinesia, akinesia, rigidity, and tremor. The analysis of patients' fine motor control, particularly handwriting, is a powerful tool to support PD…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Moises Diaz , Momina Moetesum , Imran Siddiqi , Gennaro Vessio

Posturography is routinely used to qualitatively assess one of the cardinal symptoms of Parkinson's disease -- postural instability. While most measures of balance control are derived from displacement of the center of pressure there is…

Neurons and Cognition · Quantitative Biology 2017-10-24 Miroslaw Latka , Slawomir Budrewicz , Klaudia Kozlowska , Magdalena Koszewicz , Bruce J. West

Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common neurodegenerative disorders in humans. Because a significant percentage of patients have clinical and pathological features of both diseases, it has been…

Quantitative Methods · Quantitative Biology 2019-06-10 Dhruv Agarwal , Abhishek Srivastava , Edward W Huang

In this paper, we envision a web-based framework that can help anyone, anywhere around the world record a short speech task, and analyze the recorded data to screen for Parkinson's disease (PD). We collected data from 726 unique…

Accurate diagnosis is crucial for preventing the progression of Parkinson's, as well as improving the quality of life with individuals with Parkinson's disease. In this paper, we develop a sex-specific and age-dependent classification…

Machine Learning · Computer Science 2020-01-01 Ujjwal Gupta , Hritik Bansal , Deepak Joshi