English

An improved sex specific and age dependent classification model for Parkinson's diagnosis using handwriting measurement

Machine Learning 2020-01-01 v6 Signal Processing Neurons and Cognition Machine Learning

Abstract

Accurate diagnosis is crucial for preventing the progression of Parkinson's, as well as improving the quality of life with individuals with Parkinson's disease. In this paper, we develop a sex-specific and age-dependent classification method to diagnose the Parkinson's disease using the online handwriting recorded from individuals with Parkinson's(n=37;m/f-19/18;age-69.3+-10.9years) and healthy controls(n=38;m/f-20/18;age-62.4+-11.3 years).The sex specific and age dependent classifier was observed significantly outperforming the generalized classifier. An improved accuracy of 83.75%(SD+1.63) with female specific classifier, and 79.55%(SD=1.58) with old age dependent classifier was observed in comparison to 75.76%(SD=1.17) accuracy with the generalized classifier. Finally, combining the age and sex information proved to be encouraging in classification. We performed a rigorous analysis to observe the dominance of sex specific and age dependent features for Parkinson's detection and ranked them using the support vector machine(SVM) ranking method. Distinct set of features were observed to be dominating for higher classification accuracy in different category of classification.

Keywords

Cite

@article{arxiv.1904.09651,
  title  = {An improved sex specific and age dependent classification model for Parkinson's diagnosis using handwriting measurement},
  author = {Ujjwal Gupta and Hritik Bansal and Deepak Joshi},
  journal= {arXiv preprint arXiv:1904.09651},
  year   = {2020}
}

Comments

Journal of Computer Methods and Programs in Biomedicine(Accepted on 27 December 2019)