Related papers: Estimating SARS-CoV-2 transmission in educational …
Understanding the impact of different social interactions is key to improving epidemic models. Here, we use extensive registry data -- including PCR test results and population-level networks -- to investigate the impact of school, family,…
Superspreading complicates the study of SARS-CoV-2 transmission. I propose a model for aggregated case data that accounts for superspreading and improves statistical inference. In a Bayesian framework, the model is estimated on German data…
We investigate transmission dynamics for SARS-CoV-2 on a real network of classes at Simon Fraser University, a medium-sized school in Western Canada. Outbreaks are simulated over the course of one semester across numerous parameter settings…
Background: While increasing the ventilation rate is an important measure to remove inhalable virus-laden respiratory particles and lower the risk of infection, direct validation in schools with population-based studies is far from…
Solid estimates describing the clinical course of SARS-CoV-2 infections are still lacking due to under-ascertainment of asymptomatic and mild-disease cases. In this work, we quantify age-specific probabilities of transitions between stages…
We estimate the reduction in transmission of SARS-CoV-2 achievable by surveillance testing of a susceptible population at different frequencies, comparing the cases of both the original Wuhan strain and the Delta variant. We estimate the…
Network scientists have proposed that infectious diseases involving person-to-person transmission may be effectively halted by targeting interventions at a minority of highly connected individuals. Can this strategy be effective in…
The response of many governments to the COVID-19 pandemic has involved measures to control within- and between-household transmission, providing motivation to improve understanding of the absolute and relative risks in these contexts. Here,…
Although close contact represents an important contagion route, the mechanism of exposure to exhaled droplets remains insufficiently characterized. In this study, an integrated risk assessment is presented for SARS-CoV-2 close contact…
The collection of updated data on social contact patterns following the COVID-19 pandemic disruptions is crucial for future epidemiological assessments and evaluating non-pharmaceutical interventions (NPIs) based on physical distancing. We…
The Covid-19 pandemic has taken millions of lives, demonstrating the tragedy and disruption of respiratory diseases, and how difficult they can be to manage. However, there is still significant debate in the scientific community as to which…
The debate on the role of school closures as a mitigation strategy against the spread of Covid-19 is gaining relevance due to emerging variants in Europe. According to WHO, decisions on schools "should be guided by a risk-based approach".…
SARS-CoV-2 causing COVID-19 disease has moved rapidly around the globe, infecting millions and killing hundreds of thousands. The basic reproduction number, which has been widely used and misused to characterize the transmissibility of the…
A comprehensive retrospective analysis of public health interventions, such as large scale testing, quarantining, and contact tracing, can help identify mechanisms most effective in mitigating COVID-19. We investigate China based SARS-CoV-2…
Infectious disease transmission dynamics are particularly sensitive to social contact patterns, and the precautions people take to limit disease transmission. It depends on the age distribution of the community. Thus, knowing the…
We analyzed 5,484 close contacts of COVID-19 cases from Italy, all of them tested for SARS-CoV-2 infection. We found an infection fatality ratio of 2.2% (95%CI 1.69-2.81%) and identified male sex, age >70 years, cardiovascular…
We quantified the probability of developing symptoms (respiratory or fever \geq 37.5 {\deg}C) and critical disease (requiring intensive care or resulting in death) of SARS-CoV-2 positive subjects. 5,484 contacts of SARS-CoV-2 index cases…
Background. During 2021, the COVID-19 pandemic was characterized by the emergence of lineages with increased fitness. For most of these variants, quantitative information is scarce on epidemiological quantities such as the incubation period…
Identifying the relative importance of the different transmission routes of the SARS-CoV-2 virus is an urgent research priority. To that end, the different transmission routes, and their role in determining the evolution of the Covid-19…
Accurately estimating the effectiveness of stay-at-home orders (SHOs) on reducing social contact and disease spread is crucial for mitigating pandemics. Leveraging individual-level location data for 10 million smartphones, we observe that…