English
Related papers

Related papers: Bond-Selective Intensity Diffraction Tomography

200 papers

Dual-comb spectroscopy is a promising method for precise optical spectrum analysis with fast data acquisition speed. However, its implementation and applications are often hindered by the complexity of optical comb systems. Here, as a…

Optics · Physics 2020-11-11 Zhen Zhang , Haiyun Xia , Saifen Yu , Lijie Zhao , Tianwen Wei , Manyi Li

In-vacuum active pixel detectors enable high sensitivity, highly parallel time- and space-resolved detection of ions from complex surfaces. For the first time, a Timepix detector assembly was combined with a Secondary Ion Mass Spectrometer…

Instrumentation and Detectors · Physics 2013-09-05 András Kiss , Julia H. Jungmann , Donald F. Smith , Ron M. A. Heeren

Nanoscale fabrication and characterisation techniques critically underpin a vast range of fields, including materials science, nanoelectronics and nanobiotechnology. Focused ion beam (FIB) techniques are particularly appealing due to their…

Coherent diffractive imaging (CDI) enables lensless imaging with experimental simplicity and a flexible field of view, yet its resolution is fundamentally constrained by the Abbe diffraction limit. To overcome this limitation, we introduce…

Computerized tomography (CT) has been used for decades by medical professionals to detect and diagnose injuries and ailments. CT scanners are based on interesting physics, but due to their bulk, cost, and safety, hands on experience with a…

Physics Education · Physics 2021-01-28 Vincent Daley , Owen Paetkau , Mark Paetkau

We present a new imaging technique, swept-angle synthetic wavelength interferometry, for full-field micron-scale 3D sensing. As in conventional synthetic wavelength interferometry, our technique uses light consisting of two…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Alankar Kotwal , Anat Levin , Ioannis Gkioulekas

Speckle-based phase-contrast X-ray imaging (SB-PCXI) can reconstruct high-resolution images of weakly-attenuating materials that would otherwise be indistinguishable in conventional attenuation-based imaging. The experimental setup of…

Medical Physics · Physics 2023-07-31 Samantha J. Alloo , Kaye S. Morgan , David M. Paganin , Konstantin M. Pavlov

Targeting dynamic spatially-extended phenomena in the upper solar atmosphere, a new instrument concept has been developed and tested at the Dunn Solar Telescope in New Mexico, USA, that provides wide-field, rapid-scanning, high-resolution…

Instrumentation and Methods for Astrophysics · Physics 2018-09-17 Thomas A. Schad , Haosheng Lin

Spectral molecular imaging is a new imaging technique able to discriminate and quantify different components of tissue simultaneously at high spatial and high energy resolution. Our MARS scanner is an x-ray based small animal CT system…

We demonstrate that in situ coherent diffractive imaging (CDI), which harnesses the coherent interference between a strong and a weak beam illuminating a static and dynamic structure, can be a very dose-efficient imaging method. At low…

High throughput real-time instruments are needed to acquire large data sets for detection and classification of rare events. Enabled by the photonic time stretch digitizer, a new class of instruments with record throughputs have led to the…

Optics · Physics 2015-03-20 Bahram Jalali , Ata Mahjoubfar , Claire L. Chen

Minfrared spectroscopic imaging (MIRSI) is an emerging class of label-free, biochemically quantitative technologies targeting digital histopathology. Conventional histopathology relies on chemical stains that alter tissue color. This…

Image and Video Processing · Electrical Eng. & Systems 2022-07-26 Mahsa Lotfollahi , Nguyen Tran , Sebastian Berisha , Chalapathi Gajjela , Zhu Han , David Mayerich , Rohith Reddy

It is generally assumed that a high spatial resolution of a microscope requires a large numerical aperture of the imaging lens or detector. In this study, the information limit of 15 pm is achieved in transmission electron microscopy using…

Materials Science · Physics 2024-01-08 Haozhi Sha , Jizhe Cui , Wenfeng Yang , Rong Yu

Lock-in Thermography (LIT) is a type of Infrared Thermography (IRT) that can be used as a useful non-destructive testing (NDT) technique for the detection of subsurface anomalies in objects. Currently, LIT fails to estimate the thickness at…

Applied Physics · Physics 2019-03-08 Xiao Tian , Meng Yuan Yin , Kok Hin Henry Goh

Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…

Medical Physics · Physics 2016-11-15 Wei Zhao , Lu Wan , Bo Zhang , Qiude Zhang , Tianye Niu

Mid-infrared hyperspectral imaging has become an indispensable tool to spatially resolve chemical information in a wide variety of samples. However, acquiring three-dimensional data cubes is typically time-consuming due to the limited speed…

Optics · Physics 2026-05-29 Jianan Fang , Kun Huang , Ruiyang Qin , Yan Liang , E Wu , Ming Yan , Heping Zeng

Frequency comb spectroscopy provides broadband access to molecular fingerprints with mode-defined spectral resolution. However, its deployment in non-cooperative gas sensing remains challenging because conventional implementations require…

Real-time monitoring of dynamic biological processes in the body is critical to understanding disease progression and treatment response. This data, for instance, can help address the lower than 50% response rates to cancer immunotherapy.…

Long wavelength infrared (8-13 $\mu$m) spectroscopy is invaluable for detecting molecular features in the atmospheres of gas giant and terrestrial exoplanets. The nulling-optimized mid-infrared camera (NOMIC) on the Large Binocular…

Earth and Planetary Astrophysics · Physics 2024-07-08 Brittany E. Miles , Steve Ertel , Kevin Wagner , Daniel Apai

While advancing a physics-based comprehensive photodetector-simulation model, we propose a novel device design of the mid-wavelength infrared nBn photodetectors by exploiting the inherit flexibility of the $InAs_{1-x}Sb_{x}$ ternary alloy…

Mesoscale and Nanoscale Physics · Physics 2023-10-03 Rohit Kumar , Bhaskaran Muralidharan