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Motivated by recent experiments on intracellular calcium dynamics, we study the general issue of fluctuation-induced nucleation of waves in excitable media. We utilize a stochastic Fitzhugh-Nagumo model for this study, a spatially-extended…

Condensed Matter · Physics 2009-11-10 Herve Henry , Herbert Levine

This study introduces a novel auditory neuronal network model that integrates speech signal input, cochlear processing, and a cortical excitatory-inhibitory (E-I) balanced network. Our findings reveal that increasing noise intensity…

Neurons and Cognition · Quantitative Biology 2025-12-09 Duoyu Feng , Jiajia Li

In this work, a three-dimensional multicomponent reaction-diffusion model has been developed, combining excitable-system dynamics with diffusion processes and sharing conceptual features with the FitzHugh-Nagumo model. Designed to capture…

Machine Learning · Computer Science 2025-10-29 Anastasia-Maria Leventi-Peetz , Jörg-Volker Peetz , Kai Weber , Nikolaos Zacharis

Stochasticity (or noise) at cellular and molecular levels has been observed extensively as a universal feature for living systems. However, how living systems deal with noise while performing desirable biological functions remains a major…

Molecular Networks · Quantitative Biology 2020-01-22 Qing Nie , Lingxia Qiao , Yuchi Qiu , Lei Zhang , Wei Zhao

We use particle dynamics simulations to probe the correlations between noise and dynamics in a variety of disordered systems, including superconducting vortices, 2D electron liquid crystals, colloids, domain walls, and granular media. The…

Superconductivity · Physics 2009-11-10 C. J. Olson Reichhardt , C. Reichhardt

The influence of time delay in systems of two coupled excitable neurons is studied in the framework of the FitzHugh-Nagumo model. Time-delay can occur in the coupling between neurons or in a self-feedback loop. The stochastic…

Pattern Formation and Solitons · Physics 2009-11-13 E. Schoell , G. Hiller , P. Hoevel , M. A. Dahlem

From spiking activity in neuronal networks to force chains in granular materials, the behavior of many real-world systems depends on a network of both strong and weak interactions. These interactions give rise to complex and higher-order…

Quantitative Methods · Quantitative Biology 2021-01-12 Ann S. Blevins , Jason Z. Kim , Danielle S. Bassett

While noise is generally associated with uncertainties and often has a negative connotation in engineering, living organisms have evolved to adapt to (and even exploit) such uncertainty to ensure the survival of a species or implement…

Molecular Networks · Quantitative Biology 2022-09-29 Corentin Briat , Mustafa Khammash

Despite the huge number of neurons composing a brain network, ongoing activity of local cell assemblies composing cortical columns is intrinsically stochastic. Fluctuations in their instantaneous rate of spike firing $\nu(t)$ scale with the…

Neurons and Cognition · Quantitative Biology 2024-04-15 Gianni V. Vinci , Roberto Benzi , Maurizio Mattia

Models of biological processes are often subject to different sources of noise. Developing an understanding of the combined effects of different types of uncertainty is an open challenge. In this paper, we study a variant of the…

Populations and Evolution · Quantitative Biology 2018-03-28 Francisco Herrerías-Azcué , Tobias Galla

We investigate the performance of sparsely-connected networks of integrate-and-fire neurons for ultra-short term information processing. We exploit the fact that the population activity of networks with balanced excitation and inhibition…

Neurons and Cognition · Quantitative Biology 2007-05-23 Julien Mayor , Wulfram Gerstner

Transient properties of different physical systems with metastable states perturbed by external white noise have been investigated. Two noise-induced phenomena, namely the noise enhanced stability and the resonant activation, are…

Statistical Mechanics · Physics 2008-10-07 B. Spagnolo , A. A. Dubkov , A. L. Pankratov , E. V. Pankratova , A. Fiasconaro , A. Ochab-Marcinek

Synchronization in neural networks is strongly tied to the implementation of cognitive processes, but abnormal neuronal synchronization has been linked to a number of brain disorders such as epilepsy and schizophrenia. Here we examine the…

Neurons and Cognition · Quantitative Biology 2020-02-27 Brenton Maisel , Katja Lindenberg

We elucidate how the presence of noise may significantly interact with the synchronization mechanism of systems exhibiting frequency-locking. The response of these systems exhibits a rich variety of behaviors, such as resonances and…

Statistical Mechanics · Physics 2016-08-16 D. Reguera , P. Reimann , P. Hänggi , J. M. Rubí

In this work, we consider a multi-population system where the dynamics of each agent evolve according to a system of stochastic differential equations in a general functional setup, determined by the global state of the system. Each agent…

Probability · Mathematics 2025-07-24 Giuseppe D'Onofrio , Anderson Melchor Hernandez

We perform a numerical study on the application of electromagnetic flux on a heterogeneous network of Chialvo neurons represented by a ring-star topology. Heterogeneities are realized by introducing additive noise modulations on both the…

Dynamical Systems · Mathematics 2024-02-09 Indranil Ghosh , Sishu Shankar Muni , Hammed Olawale Fatoyinbo

Brain functions require both segregated processing of information in specialized circuits, as well as integration across circuits to perform high-level information processing. One possible way to implement these seemingly opposing demands…

We study the interplay between noise and a positive feedback mechanism in an excitable system that generates events. We show that such a system can exhibit a bistability in the dynamics of the event generation (states of low and high…

Statistical Mechanics · Physics 2014-10-22 Justus A. Kromer , Reynaldo D. Pinto , Benjamin Lindner , Lutz Schimansky-Geier

Using the FitzHugh-Nagumo system in the excitable regime, we investigate the influence of the L{\'e}vy noise properties on the effect of coherence resonance. In particular, we demonstrate that the L{\'e}vy noise can be a constructive or…

Adaptation and Self-Organizing Systems · Physics 2024-04-23 Ivan Korneev , Anna Zakharova , Vladimir V. Semenov

Noise appears in the brain due to various sources, such as ionic channel fluctuations and synaptic events. They affect the activities of the brain and influence neuron action potentials. Stochastic differential equations have been used to…

Neurons and Cognition · Quantitative Biology 2020-06-01 P R Protachevicz , M S Santos , E G Seifert , E C Gabrick , F S Borges , R R Borges , J Trobia , J D Szezech , K C Iarosz , I L Caldas , C G Antonopoulos , Y Xu , R L Viana , A M Batista