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Recently, we have shown that the age-specific prevalence of a disease can be related to the transition rates in the illness-death model via a partial differential equation (PDE). In case of a chronic disease, we show that the PDE can be…

Populations and Evolution · Quantitative Biology 2017-12-29 Ralph Brinks

Forecasting transmission of infectious diseases, especially for vector-borne diseases, poses unique challenges for researchers. Behaviors of and interactions between viruses, vectors, hosts, and the environment each play a part in…

Applications · Statistics 2020-06-02 Stephen A Lauer , Alexandria C Brown , Nicholas G Reich

Traditional epidemic models consider that individual processes occur at constant rates. That is, an infected individual has a constant probability per unit time of recovering from infection after contagion. This assumption certainly fails…

Populations and Evolution · Quantitative Biology 2013-03-18 Guillermo Abramson , Sebastian Gonçalves , Marcelo F. C. Gomes

Coalescent models are used to study the transmission dynamics of rapidly evolving pathogens from molecular sequence data obtained from infected individuals. However coalescent parameters, such as effective population size, offer limited…

Methodology · Statistics 2025-11-14 Isaac H. Goldstein , Julia A. Palacios

Stochastic epidemic models can estimate infection and removal rates, and derived quantities such as the basic reproductive number ($R_0$), when both infection and removal times are observed. In practice, however, removal times are often…

Methodology · Statistics 2026-03-24 Seth D. Temple , Jonathan Terhorst

A delay between the occurrence and the reporting of events often has practical implications such as for the amount of capital to hold for insurance companies, or for taking preventive actions in case of infectious diseases. The accurate…

Applications · Statistics 2021-06-24 Roel Verbelen , Katrien Antonio , Gerda Claeskens , Jonas Crevecoeur

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

Dynamical Systems · Mathematics 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

This work aims to assess the risks of Covid-19 disease spread in diverse daily-life situations (referred to as scenarios) involving crowds of maskless pedestrians, mostly outdoors. More concretely, we develop a method to infer the global…

Physics and Society · Physics 2021-11-04 Willy Garcia , Simon Mendez , Baptiste Fray , Alexandre Nicolas

We use historical data about breathlessness in British coal miners and recent data about diabetes in Germany to illustrate a method for deriving the age-specific incidence from aggregated current status data, i.e. age-specific prevalence…

Methodology · Statistics 2023-03-07 Ralph Brinks

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

Count data are often subject to underreporting, especially in infectious disease surveillance. We propose an approximate maximum likelihood method to fit count time series models from the endemic-epidemic class to underreported data. The…

Methodology · Statistics 2020-08-25 Johannes Bracher , Leonhard Held

Epidemics occur in all shapes and forms: infections propagating in our sparse sexual networks, rumours and diseases spreading through our much denser social interactions, or viruses circulating on the Internet. With the advent of large…

Physics and Society · Physics 2013-09-02 Laurent Hébert-Dufresne , Antoine Allard , Jean-Gabriel Young , Louis J. Dubé

Superspreading complicates the study of SARS-CoV-2 transmission. I propose a model for aggregated case data that accounts for superspreading and improves statistical inference. In a Bayesian framework, the model is estimated on German data…

Applications · Statistics 2020-11-10 Patrick W. Schmidt

Turkey hosts almost 3.5M refugees and has to face a humanitarian emergency of unprecedented levels. We use mobile phone data to map the mobility patterns of both Turkish and Syrian refugees, and use these patterns to build data-driven…

Populations and Evolution · Quantitative Biology 2019-01-15 Paolo Bosetti , Piero Poletti , Massimo Stella , Bruno Lepri , Stefano Merler , Manlio De Domenico

It is preliminarily known that Aedes mosquitoes are very close to humans and their dwellings, also give rises to a broad spectrum of diseases: dengue, yellow fever, chikungunya. In this paper, we explore a multi-age-class model for mosquito…

Optimization and Control · Mathematics 2017-12-04 Karunia Putra Wijaya , Thomas Goetz , Edy Soewono

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

Populations and Evolution · Quantitative Biology 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

This paper generalizes a previously published differential equation that describes the relation between the age-specific incidence, remission, and mortality of a disease with its prevalence. The underlying model is a simple compartment…

Populations and Evolution · Quantitative Biology 2012-09-07 Ralph Brinks

The interplay of seasonality, the system's nonlinearities and intrinsic stochasticity is studied for a seasonally forced susceptible-exposed-infective-recovered stochastic model. The model is explored in the parameter region that…

Biological Physics · Physics 2010-10-19 Ganna Rozhnova , Ana Nunes

This paper introduces a new methodology for detecting anomalies in time series data, with a primary application to monitoring the health of (micro-) services and cloud resources. The main novelty in our approach is that instead of modeling…

Machine Learning · Computer Science 2020-07-31 Fadhel Ayed , Lorenzo Stella , Tim Januschowski , Jan Gasthaus

Models of disease spreading are critical for predicting infection growth in a population and evaluating public health policies. However, standard models typically represent the dynamics of disease transmission between individuals using…

Physics and Society · Physics 2022-06-07 Christopher A. Browne , Daniel B. Amchin , Joanna Schneider , Sujit S. Datta
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