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We present some simple mass-action systems with limit cycles that fall under the scope of the Deficiency-One Theorem. All the constructed examples are mass-conserving and their stoichiometric subspace is two-dimensional. Using the…

Dynamical Systems · Mathematics 2023-04-25 Balázs Boros , Josef Hofbauer

It is known that rank-two bimolecular mass-action systems do not admit limit cycles. With a view to understanding which small mass-action systems admit oscillation, in this paper we study rank-two networks with bimolecular source complexes…

Dynamical Systems · Mathematics 2024-01-09 Murad Banaji , Balázs Boros , Josef Hofbauer

We show that weakly reversible mass-action systems can have a continuum of positive steady states, coming from the zeroes of a multivariate polynomial. Moreover, the same is true of systems whose underlying reaction network is reversible…

Molecular Networks · Quantitative Biology 2022-09-14 Balázs Boros , Gheorghe Craciun , Polly Y. Yu

We establish that mass conserving single terminal-linkage networks of chemical reactions admit positive steady states regardless of network deficiency and the choice of reaction rate constants. This result holds for closed systems without…

Molecular Networks · Quantitative Biology 2015-03-19 Santiago Akle , Onkar Dalal , Ronan M. T. Fleming , Michael Saunders , Nicole Taheri , Yinyu Ye

We present three examples of chemical reaction networks whose ordinary differential equation scaling limit are almost identical and in all cases stable. Nevertheless, the Markov jump processes associated to these reaction networks display…

Probability · Mathematics 2018-10-16 Andrea Agazzi , Jonathan C. Mattingly

Bistability and multistationarity are properties of reaction networks linked to switch-like responses and connected to cell memory and cell decision making. Determining whether and when a network exhibits bistability is a hard and open…

Algebraic Geometry · Mathematics 2018-12-20 Elisenda Feliu , Martin Helmer

We demonstrate that strongly asymmetric limit cycles can be observed in the system of three identical ring oscillators (3-gene networks known as Repressilators) globally coupled by signal molecule diffusion added to the model in a way like…

Adaptation and Self-Organizing Systems · Physics 2022-11-18 N. Stankevich , E. Volkov

We consider stochastically modeled chemical reaction systems with mass-action kinetics and prove that a product-form stationary distribution exists for each closed, irreducible subset of the state space if an analogous deterministically…

Probability · Mathematics 2010-01-31 David F. Anderson , Gheorghe Craciun , Thomas G. Kurtz

In neuroscience, optics and condensed matter there is ample physical evidence for multistable dynamical systems, that is, systems with a large number of attractors. The known mathematical mechanisms that lead to multiple attractors are…

chao-dyn · Physics 2007-05-23 R. Vilela Mendes

Multistability of mesoscopic, driven biochemical reaction systems has implications to a wide range of cellular processes. Using several simple models, we show that one class of bistable chemical systems has a deterministic counterpart in…

Chemical Physics · Physics 2010-11-12 Yunxin Zhang , Hao Ge , Hong Qian

Biochemical models that exhibit bistability are of interest to biologists and mathematicians alike. Chemical reaction network theory can provide sufficient conditions for the existence of bistability, and on the other hand can rule out the…

Dynamical Systems · Mathematics 2008-04-28 Anne Shiu

The concept of limiting step gives the limit simplification: the whole network behaves as a single step. However, in its simplest form this idea is applicable only to the simplest linear cycles in steady states. For such the simplest cycles…

Chemical Physics · Physics 2008-06-23 A. N. Gorban , O. Radulescu

In this paper we study bifurcations in mass-action networks with two chemical species and reactant complexes of molecularity no more than two. We refer to these as planar, quadratic networks as they give rise to (at most) quadratic…

Dynamical Systems · Mathematics 2024-10-22 Murad Banaji , Balázs Boros , Josef Hofbauer

Under the assumption of mass-action kinetics, a dynamical system may be induced by several different reaction networks and/or parameters. It is therefore possible for a mass-action system to exhibit complex-balancing dynamics without being…

Dynamical Systems · Mathematics 2024-02-02 Sabina J. Haque , Matthew Satriano , Miruna-Stefana Sorea , Polly Y. Yu

In this paper, we propose a Boltzmann-type kinetic description of mass-varying interacting multi-agent systems. Our agents are characterised by a microscopic state, which changes due to their mutual interactions, and by a label, which…

Statistical Mechanics · Physics 2021-10-20 Nadia Loy , Andrea Tosin

Many reaction networks arising in applications are multistationary, that is, they have the capacity for more than one steady state; while some networks exhibit absolute concentration robustness (ACR), which means that some species…

Dynamical Systems · Mathematics 2024-11-20 Nidhi Kaihnsa , Tung Nguyen , Anne Shiu

We analyze semilinear reaction-diffusion systems that are mass controlled, and have nonlinearities that satisfy critical growth rates. The systems under consideration are only assumed to satisfy natural assumptions, namely the preservation…

Analysis of PDEs · Mathematics 2023-05-04 Chunyou Sun , Bao Quoc Tang , Juan Yang

Mass action systems capture chemical reaction networks in homogeneous and dilute solutions. We suggest a notion of generalized mass action systems that admits arbitrary nonnegative power-law rate functions and serves as a more realistic…

Dynamical Systems · Mathematics 2013-08-15 Stefan Müller , Georg Regensburger

Nonlinear normal modes are periodic orbits that survive in nonlinear many-body Hamiltonian systems, and their instability is crucial for relaxation dynamics. Here, we study the instability process of the $\pi/3$-mode in the…

Statistical Mechanics · Physics 2025-02-06 Weicheng Fu , Zhen Wang , Yong Zhang , Hong Zhao

We consider non-relativistic systems in quantum mechanics interacting through the Coulomb potential, and discuss the existence of bound states which are stable against spontaneous dissociation into smaller atoms or ions. We review the…

Atomic Physics · Physics 2009-11-10 E. A. G. Armour , J. -M. Richard , K. Varga
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